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South-eastern
view of the University Hospital with its unique architectural design.
All departments, ranging from biochemistry, animal facilities, pathology
etc. up to clinics with 1400 beds are located inside this massive block. |
Peer
Reviewed Publications in International Journals (only English) 2000-2005
Publications List:
Please refer to our website or PubMed (for example searching for “Floege”, “Mertens PR”, “Ketteler M”, “Frank D”, “Kurts
C”)
Some selected original publications of the unit are:
| 2005 |
| Kunter U, Rong S, Djuric Z, Boor P, Müller-Newen G, Yu D, Floege J: Transplanted mesenchymal stem cells accelerate glomerular healing in experimental glomerulonephritis. In revision |
| Ostendorf T, Rong S, Wiedemann S, Kunter U, Haubold U, van Roeyen CRC, Eitner F, Kawachi H, Starling G, Alvarez E, Smithson G, Floege J: Antagonism of PDGF-D by the human antibody CR002 prevents renal scarring in experimental glomerulonephritis. In revision |
| Van Roeyen CRC, Ostendorf T, Bokemeyer D, Behrmann I, Denecke B, Jahnen-Dechent W, Strutz F, Lichenstein HS, LaRochelle WJ, Floege J: Biological responses to PDGF-BB versus PDGF-DD in human mesangial cells. In revision |
| Van Roeyen CRC, Eitner F, Martinkus S, Thieltges SR, Ostendorf T, Bokemeyer D, Lüscher B, Lüscher-Firzlaff JM, Floege J, Mertens PR: Y-box protein 1 activation is a crucial event for platelet-derived growth factor-B downstream signaling in mesangioproliferative glomerular disease. J. Am. Soc. Nephrol. 2005 in press |
| Brandenburg VM, Ketteler M, Heussen N, Pollit D, Frank RD, Westenfeld R, Ittel T, Floege J: Lumbar bone mineral density in very long-term renal transplant recipients: Impact of circulating sex hormones. Osteoporosis Int 2005 in press |
| Breitkopf K, van Roeyen C, Sawitza I, Wickert L, Floege J, Gressner AM: Expression patterns of PDGF-A, -B, -C and -D and the PDGF-receptors alpha and beta in activated rat hepatic stellate cells (HSC). Cytokine 2005 in press |
| Schurgers LJ , Teunissen KJ , Knapen MH , Geusens P , van der Heijde D , Kwaijtaal M , van Diest R , Ketteler M , Vermeer C . Characteristics and performance of an immunosorbent assay for human matrix Gla-protein. Clin Chim Acta. 2005 Jan;351(1-2):131-8. |
| Mehrotra R , Westenfeld R , Christenson P , Budoff M , Ipp E , Takasu J , Gupta A , Norris K , Ketteler M , Adler S . Serum fetuin-A in nondialyzed patients with diabetic nephropathy: relationship with coronary artery calcification. Kidney Int. 2005 Mar;67:1070-7. |
| Moe SM , Reslerova M , Ketteler M , O'neill K , Duan D , Koczman J , Westenfeld R , Jahnen-Dechent W , Chen NX . Role of calcification inhibitors in the pathogenesis of vascular calcification in chronic kidney disease (CKD). Kidney Int. 2005 Jun;67:2295-304. |
| Merx MW , Schafer C , Westenfeld R , Brandenburg V , Hidajat S , Weber C , Ketteler M , Jahnen-Dechent W . Myocardial Stiffness, Cardiac Remodeling, and Diastolic Dysfunction in Calcification-Prone Fetuin-A-Deficient Mice. Am Soc Nephrol. 2005 Sep 21; [Epub ahead of print] |
| En-Nia A , Yilmaz E , Klinge U , Lovett DH , Stefanidis I , Mertens PR . Transcription factor YB-1 mediates DNA polymerase alpha gene expression. J Biol Chem. 2005;280:7702-11. |
| Stefanidis I , Wurth P , Mertens PR , Ikonomov V , Philippidis G , Golphinopoulos S , Makropoulos V , Liakopoulos V , Mann H , Heintz B . Plasma Endothelin-1 in Hemodialysis Treatment - the Influence of Hypertension. J Cardiovasc Pharmacol. 2004 Nov;44:S43-S48. |
| Stefanidis I , Bach R , Mertens PR , Liakopoulos V , Liapi G , Mann H , Heintz B Influence of hemodialysis on the mean blood flow velocity in the middle cerebral artery. Clin Nephrol. 2005; 64: 129-37. |
| Filippidis G , Liakopoulos V , Mertens PR , Kiropoulos T , Stakias N , Verikouki C , Patsidis E , Koukoulis G , Stefanidis I . Resistin Serum Levels Are Increased but Not Correlated with Insulin Resistance in Chronic Hemodialysis Patients. Blood Purif. 2005; 23:421-428 |
| Liakopoulos V , Wurth P , Mertens PR , Eleftheriadis T , Kourti P , Georgios V , Heintz B , Koukoulis GN , Stefanidis I . Endothelin-1 plasma levels in hemodialysis treatment--the influence of type 2 diabetes. Ren Fail. 2005;27:515-22. |
| Haubitz M, Wittke S, Weissinger EM, Walden M, Rupprecht HD, Floege J, Haller H, Mischak H: Urine protein patterns can serve as diagnostic tools in patients with IgA nephropathy. Kidney Int. 67 (2005):2313-20 |
| Yu D, Petermann A, Kunter U, Rong S, Shankland SJ, Floege J: Urinary Podocyte Loss Is a More Specific Marker of Ongoing Glomerular Damage than Proteinuria. J Am Soc Nephrol. (2005) Epub ahead of print |
| Moeller MJ, Soofi A, Sanden SK, Floege J, Kriz W, Holzman LB: An efficient system for tissue-specific over-expression of transgenes in podocytes in vivo. Am J Physiol Renal Physiol (2005) Epub ahead of print |
| Lang A, Benke D, Eitner F, Engel D, Ehrlich S, Breloer M, Hamilton-Williams E, Specht S, Hoerauf A, Floege J, von Bonin A, Kurts C:Heat shock protein 60 is released in immune-mediated glomerulonephritis and aggravates disease: in vivo evidence for an immunologic danger signal. J Am Soc Nephrol. 16 (2005):383-91 |
| Panzer U, Schneider A, Steinmetz OM, Wenzel U, Barth P, Reinking R, Becker JU, Harendza S, Zahner G, Fischereder M, Kramer BH, Schlondorff D, Ostendorf T, Floege J, Helmchen U, Stahl RA: The chemokine receptor 5 Delta32 mutation is associated with increased renal survival in patients with IgA nephropathy. Kidney Int. 67 (2005):75-81 |
| Milovanceva-Popovska, M., Kunter, U., Ostendorf, T., Petermann, A., Rong, S., Eitner, F., Kerjaschki, D., Barnett, A., Floege J: R-roscovitine (CYC202) alleviates renal cell proliferation in nephritis without aggravating podocyte injury. Kidney Int 67 (2005): 1362-70 |
| 2004 |
| Brandenburg VM, Gaertner S, Lindemann-Docter K, Ortlepp JR, Westerhuis R, Ketteler M, Westenfeld R, Floege J: Underestimated complications in thrombotic thrombocytopenic purpura/haemolytic uraemic syndrome. Nephrol. Dial. Transplant. 2004; 19:2142-2146. |
| Brandenburg VM, Politt D, Ketteler M, Fassbender WJ, Heussen N, Westenfeld R, Freuding T, Floege J, Ittel TH: Early rapid loss followed by long-term consolidation characterizes the development of lumbar bone mineral density after kidney transplantation. Transplantation 2004; 77:1566-1571. |
| Brandenburg VM, Frank RD, Heintz B, Rath W, Bartz C: HELLP syndrome, multifactorial thrombophilia and postpartum myocardial infarction. J. Perinat. Med. 2004; 32:181-183. |
| Brandenburg VM, Knackstedt C, Gobbele R, Graf J, Schroder J, Westerhuis R, Kosinski CM: Hypokaliämische Lähmung bei Hyperthyreose. Nervenarzt 2004; 75:1007-1011. |
| Christen U, Benke D, Wolfe T, Rodrigo E, Rhode A, Hughes AC, Oldstone MB, von Herrath MG: Cure of prediabetic mice by viral infections involves lymphocyte recruitment along an IP-10 gradient.. J Clin Invest. 2004;113:74-84 |
| Frank RD, Brandenburg VM, Lanzmich R, Floege J: Factor Xa-activated whole blood clotting time (Xa-ACT) for bedside monitoring of dalteparin anticoagulation during haemodialysis. Nephrol. Dial. Transplant. 2004; 19:1552-1558. |
| Krüger T, Benke D, Eitner F, Lang A, Wirtz M, Hamilton-Williams EE, Engel D, Giese B, Müller-Newen G, Floege J, Kurts C: Identification and functional characterization of dendritic cells in the healthy murine kidney and in experimental glomerulonephritis. J. Am. Soc. Nephrol. 2004; 15: 613-621. |
| Liakopoulos V, Petinaki E, Bouchlariotou S, Mertens PR, Trakala M, Kourti P, Riehl J, Ikonomov V, Stefanidis I : Group B Streptococcus (Streptococcus agalactiae) peritonitis associated with continuous ambulatory peritoneal dialysis (CAPD). Clin. Nephrol. 2004; 62:391-396. |
| Lynen Jansen P, Klinge U, Anurov M, Titkova S, Mertens PR, Jansen M: Surgical mesh as a scaffold for tissue regeneration in the esophagus. Eur. Surg. Res. 2004; 36:104-111. |
| Moeller MJ, Soofi A, Braun GS, Li X, Watzl C, Kriz W, Holzman LB: Protocadherin FAT1 binds Ena/VASP proteins and is necessary for actin dynamics and cell polarization. EMBO J. 2004;23:3769-79 |
| Mühlfeld AS, Segerer S, Hudkins K, Farr AG, Kraus D, Holers VM, Quigg RJ, Alpers CE: Overexpression of complement inhibitor Crry does not prevent cryoglobulin-associated membranoproliferative glomerulonephritis. Kidney Int. 2004; 65:1214-1223. |
| Mühlfeld AS, Wen M, Hudkins KL, Kirk E, LeBoeuf RC, Alpers CE: Hyperlipidemia aggravates renal disease in ROP os/+ mice. Kidney Int. 2004; 66:1393-1402. |
| Musi B, Braide M, Carlsson O, Wieslander A, Albrektsson A, Ketteler M, Westenfeld R, Floege J, Rippe B: Biocompatibility of peritoneal dialysis fluids: long-term exposure of nonuremic rats. Perit. Dial. Int. 2004; 24:37-47. |
| Ostendorf T, Van Roeyen C, Westenfeld R, Gawlik A, Kitahara M, De Heer E, Kerjaschki D, Floege J, Ketteler M: Inducible nitric oxide synthase-derived nitric oxide promotes glomerular angiogenesis via upregulation of vascular endothelial growth factor receptors. J. Am. Soc. Nephrol. 2004; 15:2307-2319. |
| Pawlinski R, Pedersen B, Schabbauer G, Tencati M, Holscher T, Boisvert W, Andrade-Gordon P, Frank RD, Mackman N. Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia. Blood 2004; 103:1342-1347. |
| Peters H, Eisenberg R, Daig U, Liefeldt L, Westenfeld R, Gaedeke J, Kramer S, Neumayer HH. Platelet inhibition limits TGF-beta overexpression and matrix expansion after induction of anti-thy1 glomerulonephritis. Kidney Int. 2004; 65:2238-2248. |
| Politt D, Heintz B, Floege J, Mertens PR: Tacrolimus- (FK 506) based immunosuppression in severe systemic lupus erythematosus. Clin. Nephrol. 2004; 62:49-53. |
| Raffetseder U, Wernert N, Ostendorf T, van Roeyen C, Rauen T, Behrens P, Floege J, Mertens PR: Mesangial cell expression of proto-oncogene Ets-1 during progression of mesangioproliferative glomerulonephritis. Kidney Int. 2004; 66:622-632. |
| Schlieper G, Kim JH, Molojavyi A, Jakoby C, Laussmann T, Flogel U, Godecke A, Schrader J: Adaptation of the myoglobin knockout mouse to hypoxic stress. Am. J. Physiol. 2004; 286:R86-92. |
| Stefanidis I, Wurth P, Mertens PR, Ikonomov V, Philippidis G, Golphinopoulos S, Makropoulos V, Liakopoulos V, Mann H, Heintz B. Plasma endothelin-1 in hemodialysis treatment - the influence of hypertension. J Cardiovasc Pharmacol. 2004;44:43-48 |
| Steinmetz OM, Panzer U, Harendza S, Mertens PR, Ostendorf T, Floege J, Helmchen U, Stahl RA: No association of the -2518 MCP-1 A/G promoter polymorphism with incidence and clinical course of IgA nephropathy. Nephrol. Dial. Transplant. 2004; 19:596-601. |
| Wasmuth HE, Kunz D, Graf J, Stanzel S, Purucker EA, Koch A, Gartung C, Heintz B, Gressner AM, Matern S, Lammert F. Hyperglycemia at admission to the intensive care unit is associated with elevated serum concentrations of interleukin-6 and reduced ex vivo secretion of tumor necrosis factor-alpha. Crit Care Med. 2004;32:1109-14 |
| Wen M, Mühlfeld AS, Segerer S, Hudkins KL, Kirk E, LeBoeuf RC, Alpers CE: Hyperglycemia and hyperlipidemia act synergistically to induce renal disease in LDL receptor deficient BALB mice. Am. J. Nephrol. 2004; 24:20-31. |
| 2003 |
| Schmidt T, Brandenburg VM, Kruger S, Haage P: Situs inversus and severe pulmonary hypertension. Lancet. 2003; 361:820. |
| Schafer C, Heiss A, Schwarz A, Westenfeld R, Ketteler M, Floege J, Muller-Esterl W, Schinke T, Jahnen-Dechent W: The serum protein alpha 2-Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification.J Clin Invest. 2003; 112: 357-66. |
| Raffetseder U, Frye B, Rauen T, Jürchott K, Royer H.D., Mertens P.R: Splicing factor SRp30c interaction with Y-box protein-1 confers nuclear YB-1 shuttling and alternative splice site selection. J Biol Chem. 2003; 278: 18241-18248. |
| Peters H, Ruckert M, Gaedeke J, Liefeldt L, Ketteler M, Sharma AM, Neumayer HH: Angiotensin-converting enzyme inhibition but not beta-adrenergic blockade limits transforming growth factor-beta overexpression in acute normotensive anti-thy1 glomerulonephritis. J Hypertens. 2003; 21: 771-80. |
| Petermann AT, Pippin J, Hiromura K, Monkawa T, Durvasula R, Couser WG, Kopp J, Shankland SJ: Mitotic cell cycle proteins increase in podocytes despite lack of proliferation. Kidney Int. 2003; 63: 113-22. |
| Pippin JW, Durvasula R, Petermann A, Hiromura K, Couser WG, Shankland SJ: DNA damage is a novel response to sublytic complement C5b-9-induced injury in podocytes. J Clin Invest. 2003; 111: 877-85. |
| Griffin SV, Petermann AT, Durvasula RV, Shankland SJ: Podocyte proliferation and differentiation in glomerular disease: role of cell-cycle regulatory proteins. Nephrol Dial Transplant. 2003; Suppl 6:vi8-13. |
| Petermann AT, Krofft R, Blonski M, Hiromura K, Vaughn M, Pichler R, Griffin S, Wada T, Pippin J, Durvasula R, Shankland SJ: Podocytes that detach in experimental membranous nephropathy are viable. Kidney Int. 2003; 64: 1222-31. |
| Pawlinski R, Pedersen B, Kehrle B, Aird WC, Frank RD, Guha M, Mackman N: Regulation of tissue factor and inflammatory mediators by Egr-1 in a mouse endotoxemia model. Blood. 2003; 101: 3940-7. |
| Ostendorf T, van Roeyen CRC, Peterson JD, Kunter U, Eitner F, Hamad AJ, Chan G, Jia XC, Macaluso J, Gazit-Bornstein G, Keyt BA, Lichenstein HS, LaRochelle WJ, Floege J: A fully human monoclonal antibody (CR002) identifies PDGF-D as a novel mediator of mesangioproliferative glomerulonephritis. J Am Soc Nephrol. 2003; 14: 2237-2247. |
| Mühlfeld AS, Segerer S, Hudkins K, Carling MD, Wen M, Farr AG, Ravetch JV, Alpers CE: Deletion of the Fc g receptor IIb in TSLP transgenic mice aggravates membranoproliferative glomerulonephritis. Am J Pathol. 2003; 163: 1127-36. |
| Mühlfeld A, Kubitz R, Dransfeld O, Häussinger D, Wettstein M: Taurine supplementation induces expression of MRP2 transporter in rats and prevents LPS-induced cholestasis. Arch Biochem Biophys. 2003; 413: 32-40. |
| Mahnken AH, Brandenburg VM, Frank RD, Haage P, Gunther RW: Hemolysis, hemorrhage, headache, and hidden abortion: imaging findings in antiphospholipid syndrome. Eur Radiol. 2003 |
| Kunter U, Floege J, von Jürgensonn AS, Stojanovic T, Merkel S, Gröne HJ, Ferran C: Expression of A20 in the vessel wall of rat-kidney allografts correlates with protection from transplant arteriosclerosis. Transplantation. 2003; 75: 3-9. |
| Kriz W, Hahnel B, Hosser H, Ostendorf T, Gaertner S, Kranzlin B, Gretz N, Shimizu F, Floege J: Pathways to recovery and loss of nephrons in anti-Thy 1 nephritis. J Am Soc Nephrol. 2003; 14: 1904-1926. |
| Ketteler M, Bongartz P, Westenfeld R, Wildberger JE, Mahnken AH, Bohm R, Metzger T, Wanner C, Jahnen-Dechent W, Floege J. Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study. Lancet. 2003; 361: 827-33. |
| Janssen U, Riley SG, Vassiliadou A, Floege J, Phillips AO: Hypertension superimposed on type II diabetes in Goto Kakizaki rats induces progressive nephropathy. Kidney Int. 2003; 63: 2162-70. |
| Janssen U, Eitner F, Kunter U, Ostendorf T, Wolf G, Chaponnier C, Gabbiani G, Kerjaschki D, Floege J: Extracellular actin impairs glomerular capillary repair in experimental mesangioproliferative glomerulonephritis. Nephron Exp Nephrol. 2003; 93: e158-167 |
| Geier A., Mertens P.R., Gerloff T., Dietrich C.G., En-Nia A., Kullak-Ublick G.A., Karpen S.J., Matern S., Gartung C: Constitutive rat multidrug-resistance protein 2 gene transcription is down-regulated by Y-box protein 1. Biochem Biophys Res Commun. 2003; 309: 612-8. |
| Eitner F, Ostendorf T, Kretzler M, Cohen CD, Eriksson U, Gröne HJ, Floege J : PDGF-C expression in the developing and normal adult human kidney and in glomerular diseases. J Am Soc Nephrol. 2003; 14: 1145-1153 |
| Dagtekin G, Schiffer R, Klein B, Jahnen-Dechent W, Zwadlo-Klarwasser G: Modulation of angiogenic functions in human macrophages by biomaterials. Biomaterials. 2003;24:3395-401. |
| Brandenburg VM, Schubert H: Images in clinical medicine. Pulmonary alveolar microlithiasis. N Engl J Med. 2003; 348: 1555 |
| Brandenburg VM, Frank RD, Janssen U, Wurth P, Floege J , Riehl J: Ultrasonographic fata morgana. Nephrol Dial Transplant. 2003; 18: 845-846. |
Brandenburg VM , Ketteler M , Fassbender WJ, Heussen N, Freuding T, Floege J , Ittel TH : Development of lumbar bone mineral density in the late course after kidney transplantation. Am J Kidney Dis. 2003; 40: 1066-74 |
| 2002 |
| Raffetseder U, Frye B, Rauen T, Jürchott K, Royer HD, Mertens PR: Splicing factor SRp30c interaction with Y-box protein-1 confers nuclear YB-1 shuttling and alternative splice site selection. Submitted. |
| Eitner F, Ostendorf T, Kretzler M, Cohen CD, Eriksson U, Groene HJ, Floege J: PDGF-C expression in the developing and normal adult human kidney and in glomerular diseases. Submitted. |
| Westerhuis R, Kitahara M, Daha MR, Floege J, Roos A: Interaction of MBL with IgA induces complement activation on the surface of human mesangial cells. Submitted. |
| Ketteler M, Bongartz P, Westenfeld R, Wildberger JE, Mahnken AH, Böhm R, Metzger T, Wanner C, Jahnen-Dechent W, Floege J: Cardiovascular mortality in dialysis patients: Low Ahsg/fetuin serum levels may be a critical factor. In revision |
| Kunter U, Floege J, von Jürgensonn AS, Stojanovic T, Merkel S, Groene HJ, Ferran C: Expression of A20 in the vessel wall of rat kidney allografts correlates with protection from transplant arteriosclerosis. Transplantation in press |
| Mertens PR, Steinmann K, Alfonso-Jaume MA, En-Nia A, Sun Y, Lovett DH: Combinatorial interactions of p53, activating protein-2, and YB-1 with a single enhancer element regulate gelatinase A expression in neoplastic cells. J Biol Chem. 277 (2002): 24875-24882. |
| Brandenburg V, Ketteler M, Fassbender WJ, Heussen N, Freuding T, Floege J, Ittel TH: Development of lumbar bone mineral density in the late course following kidney transplantation. Am J Kidney Dis. 40 (2002): 1066-74. |
| Gaertner SA, Janssen U, Ostendorf T, Koch KM, Floege J, Gwinner W: Glomerular oxidative and antioxidative systems in experimental mesangioproliferative glomerulonephritis. J Am Soc Nephrol. 13 (2002):2930-2937. |
| Reisdorf J, En-Nia A, Stefanidis I, Floege J, Lovett DH, Mertens PR: Transcription factor ets-1 regulates gelatinase A gene expression in mesangial cells. J. Am. Soc. Nephrol. 13 (2002): 1568-78 |
| Kitahara M, Eitner F, Ostendorf T, Janssen U, Kunter U, Westenfeld R, Matsui K, Kerjaschki D, Floege J: Selective cyclooxygenase-2 inhibition impairs glomerular capillary healing in experimental glomerulonephritis. J. Am. Soc. Nephrol. 13 (2002): 1261-70 |
| Bokemeyer D, Lindemann M, Kitahara M, Kerjaschki D, Trzaskos JM, Floege J, Kramer HJ, Ostendorf T: In vivo inhibition of the MAP-kinase cascade blunts the progression of mesangioproliferative glomerulonephritis. J. Am. Soc. Nephrol. 13 (2002): 1473-80 |
| Eitner F, Ostendorf T, Van Roeyen C, Kitahara M, Li X, Aase K, Groene HJ, Eriksson U, Floege J: Expression of a novel PDGF isoform, PDGF-C, in normal and diseased rat kidney. J. Am. Soc. Nephrol. 13 (2002): 910-917. |
| Westenfeld R, Gawlik A, de Heer E, Kitahara M, Abou-Rebyeh F, Floege J, Ketteler M: Selective inhibition of inducible nitric oxide synthase enhances intraglomerular coagulation in chronic anti-thy 1-nephritis. Kidney Int. 61 (2002): 834-838. |
| En-Nia A, Reisdorff J, Stefanidis I, Floege J, Heinrich PC, Mertens PR: Mesangial cell gelatinase A synthesis is attenuated by oscillating hyperbaric pressure. Biochem J. 362 (2002) 693-700. |
| 2001 |
| Norman JT, Lindahl GE, Shakib K, En-Nia A, Yilmaz E, Mertens PR. The Y-box binding protein YB-1 suppresses collagen alpha 1(I) gene transcription via an evolutionarily conserved regulatory element in the proximal promoter. J Biol Chem. 276 (2001):29880-90. |
| Ostendorf T, Kunter U, Dooley S, Janjic N, Ruckman J, Eitner F, Floege J: The effects of PDGF antagonism in experimental glomerulonephritis are independent of the TGF-beta system. J. Am. Soc. Nephrol. 13 (2002): 658-667. |
| Frank D, Weber J, Dresbach H, Thelen H, Floege J: The role of contact system activation in hemodialyzer-induced thrombogenicity: insights derived from a new ex vivo recirculation model. Kidney Int. 60 (2001): 1972-1981. |
| Kurts C, Klebba I, Davey GM, Koch KM, Miller JF, Heath WR, Floege J: Kidney protection against autoreactive CD8+ T cells distinct from immunoprivilege and sequestration. Kidney Int 60 (2001): 664-71. |
| Ostendorf T, Kunter U, Groene HJ, Kawachi H, Shimizu F, Koch KM, Janjic N, Floege J: Specific antagonism of PDGF prevents renal scarring in experimental glomerulonephritis. J Am Soc Nephrol 12 (2001): 909-18. |
| Kurts C, Cannarile M, Klebba I, Brocker T. Dendritic cells are sufficient to cross-present self-antigens to CD8 T cells in vivo. J Immunol. 166 (2001):1439-42 |
| 2000 |
| Schäffer J, Burchert W, Floege J, Gielow P, Kionka C, Linke RP, Weiss EH, Shaldon S, Koch KM: Recombinant versus natural human 111In-ß2-microglobulin for amyloid scintigraphy in hemodialysis patients. Kidney Int 58 (2000): 873-880. |
| Bokemeyer D, Ostendorf T, Kunter U, Lindemann M, Kramer HJ, Floege J: Differential activation of mitogen-activated protein kinases in experimental mesangio-proliferative glomerulonephritis. J Am Soc Nephrol 11 (2000): 232-240. |
| Janssen U, Bahlmann F, Köhl J, Zwirner J, Haubitz M, Floege J: Activation of the acute phase response and complement C3 in patients with IgA nephropathy. Am J Kidney Dis 35 (2000): 21-28. |
| Frank RD, Dresbach H, Thelen H, Sieberth HG: Glutardialdehyde induced fluorescence technique (GIFT): A new method for the imaging of platelet adhesion on biomaterials. J Biomed Mater Res. 52 (2000):374-381. |
| Joles J, Kunter U, Janssen U, Kriz W, Rabelink TJ, Floege J: Early mechanisms of renal injury in hyperlipidemic rats. J Am Soc Nephrol 11 (2000): 669-683. |
| Coimbra TM, Janssen U, Groene HJ, Ostendorf T, Kunter U, Schmidt H, Brabant G, Floege J: Early events leading to renal injury in obese Zucker (fatty) rats with type II diabetes. Kidney Int 57(2000):167-182. |
| Ostendorf T, Kunter U, Loos A, Eitner F, Regele H, Kerjaschki D, Janjic N, Floege J: Vascular endothelial growth factor (VEGF165) mediates glomerular endothelial repair. J Clin Invest 104 (1999): 913-923. |
Reviews & Editorials
| Ketteler M , Gross ML , Ritz E . Calcification and cardiovascular problems in renal failure. Kidney Int Suppl. 2005 Apr;(94):S120-7. |
| Stenvinkel P , Ketteler M , Johnson RJ , Lindholm B , Pecoits-Filho R , Riella M , Heimburger O , Cederholm T , Girndt M . IL-10, IL-6, and TNF-alpha: central factors in the altered cytokine network of uremia--the good, the bad, and the ugly. Kidney Int. 2005 Apr;67(4):1216-33 |
| Ketteler M . Fetuin-A and extraosseous calcification in uremia. Curr Opin Nephrol Hypertens. 2005 Jul;14(4):337-42. |
| Floege J : Nephrology -- familiar knowledge in the light of new discoveries in molecular and cell biology. Dtsch Med Wochenschr. 130 (2005): 1552-4 |
| Eitner F, Floege J: Therapeutic targets for prevention and regression of progressive fibrosing renal diseases. Curr. Opin. Investig. Drugs 6 (2005): 255-61 |
| Ketteler M, Brandenburg V, Jahnen-Dechent W, Westenfeld R, Floege J : Do not be misguided by guidelines: the calcium x phosphate product can be a Trojan horse. Nephrol. Dial. Transplant. 20 (2005): 673-7 |
| Brandenburg VM, Floege J: Treatment of bone disease in renal transplant recipients. Rev. Port. Nefrol. Hipert. 2004; 18:137-142. |
| Floege J, Eitner F, van Roeyen C, Ostendorf T: PDGF-D and renal disease: Yet another one of those growth factors? J Am Soc Nephrol. 2003; 14: 2690-2691 |
| Janssen U, Vassiliadou A, Riley SG, Phillips AO, Floege J: The quest for a model of type II diabetes with nephropathy: the Goto Kakizaki rat. J. Nephrol. 2004; 17:769-773. |
| Goodman WG, London G, Amann K, Block GA, Giachelli C, Hruska KA, Ketteler M, Levin A, Massy Z, McCarron DA, Raggi P, Shanahan CM, Yorioka N; Vascular Calcification Work Group: Vascular calcification in chronic kidney disease. Am. J. Kidney Dis. 2004; 43:572-579. |
| Floege J: Recurrent IgA nephropathy after renal transplantation. Semin. Nephrol. 2004; 24:287-291. |
| Floege J, Ketteler M: Vascular calcification in patients with end-stage renal disease. Nephrol. Dial. Transplant. 2004; 19 Suppl. 5:V59-V66. |
| Floege J, van Roeyen C, Ostendorf T: PDGF-D: a novel mediator of mesangioproliferative glomerulonephritis. Drug Future 2004; 29:179-184. |
| Floege J: When man turns to stone: Extraosseous calcification in uremic patients (Kidney International Forum). Kidney Int. 2004; 65:2447-2462. |
| Floege J: Recurrent IgA-nephropathy following renal transplantation. Semin. Nephrol. 2004; 24:287-291. |
| Brandenburg VM, Westenfeld R, Ketteler M: The fate of bone after renal transplantation. J. Nephrol. 2004; 17:190-204. |
| Mertens PR, Floege J: IgA-Nephropathie: Die häufigste Glomerulonephritis-Form. Dtsch med Wschr. 2003; 128: 1242-6. [ |
| Ketteler M, Wanner C, Metzger T, Bongartz P, Westenfeld R, Gladziwa U, Schurgers LJ, Vermeer C, Jahnen-Dechent W, Floege J: Deficiencies of calcium-regulatory proteins in dialysis patients: a novel concept of cardiovascular calcification in uremia. Kidney Int Suppl. 2003; 84: S84-7. |
| Ketteler M, Kunter U, Floege J: An update on herpes virus infections in graft recipients. Nephrol Dial Transplant. 2003; 18: 1703-6. |
| Hanninen A, Hamilton-Williams E, Kurts C: Development of new strategies to prevent type 1 diabetes: the role of animal models. Ann Med. 2003; 35: 546-63. |
| Frank RD, Kierdorf HP: Antikoagulation bei der Nierenersatztherapie des blutungsgefährdeten Intensivpatienten. Intensiv-News. 2003; 7: 7-10. |
| Frank RD, Kierdorf HP: Spezielle Antikoagulationsverfahren für die Nierenersatztherapie in der Intensivmedizin. Intensivmed. 2003; 40: 382-391. |
| Floege J: Recurrent glomerulonephritides following renal transplantation: an update. Nephrol Dial Transplant. 2003; 18: 1260-5 . |
| Floege J, Gröne HJ: IgA-Nephropathie: häufig, jedoch nur selten diagnostiziert. Internist. 2003; 44: 1131-1139 . |
| Floege J: Evidence-based recommendations for immunosuppression in IgA-nephropathy: handle with caution. Nephrol Dial Transplant. 2003; 18: 241-5. |
| Eitner F, Floege J: Novel insights into renal fibrosis. Curr Opin Nephrol Hypertens. 2003; 12: 227-32. |
| Brandenburg VM, Heintz B, Floege J: Therapy and prophylaxis of renal failure. Internist. 2003; 44: 819-30. |