SUBJECT CONSULTANT REVIEW

Title of the article
Randomized Controlled Trial of Intradialytic Resistance training to target muscle wasting in ESRD: the progressive exercise for anabolism in kidney disease (PEAK) Study
Authors
Cheema B, Abas H, Smith B, O’Sullivan A, Chan M, Patwardhan A, Kelly J, Gillin A, Pang G, Lloyd B, Fiatarone Singh M
Journal
Am J Kidney Dis 2007 October; 50 (4): 574 - 84
Subject Consultant
C. Basile
Score (1 to 3 stars)
**
Comments
Aim of this randomized controlled trial was to determine whether prolonged (24 weeks) intradialytic progressive resistance training (PRT) could counteract muscle wasting more effectively than short-duration training (12 weeks) in patients with end-stage renal disease. Prolonged intradialytic PRT did not significantly improve muscle cross-sectional area or intramuscular lipid content compared with a shorter duration of exercise.