| Title
of the article |
Pharmacodynamics of unfractionated heparin during and after a hemodialysis session.
|
| Authors |
Brunet P, Simon N, Opris A, Faure V, Lorec-Penet AM, Portugal H, Dussol B, Berland Y. |
| Journal
|
Am J Kidney Dis. 2008 May;51(5):789-95. |
| Subject
Consultant |
C. Basile |
| Score
(1 to 3 stars) |
** |
| Comments |
Anti-Xa activity is used as a clinical guide to anticoagulation with heparin, but heparin dosing regimens for hemodialysis were established before anti-Xa assays were developed; thus, the optimal regimen for heparin dosing was not determined. Unfractionated heparin administered by means of a 3-hour continuous infusion for hemodialysis anticoagulation provided an efficient and safe effect that quickly disappeared after the end of the session. |
