| Title
of the article |
Systemic inflammation is associated with pulmonary hypertension in patients undergoing haemodialysis.
|
| Authors |
Yu TM, Chen YH, Hsu JY, Sun CS, Chuang YW, Chen CH, Wu MJ, Cheng CH, Shu KH. |
| Journal
|
Nephrol Dial Transplant. 2009 Jun;24(6):1946-51. Epub 2009 Jan 22. |
| Subject
Consultant |
C. Basile |
| Score
(1 to 3 stars) |
** |
| Comments |
Pulmonary hypertension (PH) is an overlooked cardiovascular morbidity in patients undergoing haemodialysis. Inflammation has been demonstrated to play a significant role with certain types of PH in non-uraemic patients. This study reveals that dialyzed patients with PH have increased serum levels of acute phase reactive protein and cytokines, including IL-1β, TNF- and IL-6. A chronic inflammation might play an important role in the pathogenesis of PH in patients undergoing haemodialysis. |
