SUBJECT CONSULTANT REVIEW

Title of the article
Impact of increasing haemodialysis frequency versus haemodialysis duration on removal of urea and guanidino compounds: a kinetic analysis.
Authors

Eloot S, van Biesen W, Dhondt A, de Smet R, Marescau B, De Deyn PP, Verdonck P, Vanholder R.

Journal

Nephrol Dial Transplant. 2009 Jul;24(7):2225-32. Epub 2009 Feb 18.

Subject Consultant
C. Basile
Score (1 to 3 stars)
**
Comments
Patients with renal failure retain a large variety of uraemic solutes, characterized by different kinetic behaviour. It is not entirely clear what the impact is of increasing dialysis frequency and/or duration on removal efficiency. This study shows that prolonged dialysis significantly reduces solute concentration levels. Increasing both dialysis frequency and duration is the superior dialysis schedule.