Proteinuria in Pts with Cerebrospinal Fluid Shunts First name:   Last name:   1 Concerning Henoch-Schönlein Purpura, which of the following statements is true? HSP is rarely preceded by infections of the upper respiratory tract. A relevant diagnostic criterion is an elevation of serum IgA in virtually all affected patients. Presumed pathophysiological mechanism: IgA metabolism in HSP is characterized by abnormally glycosylated IgA molecules, reduced hepatocellular IgA uptake and degradation of these complexes. Mainstay of therapy in HSP is long-term immunosuppressive therapy. Supportive renal therapy plays a minor a role in treatment.

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