Prof G. Conte Full-professor of Nephrology at II University of Neaples and Chief of Nephrology and Dialysis “Incurabili” Hospital of Neaples Neaples, Italy	Dr P. Zamboli Senior Fellow at II University of Neaples “Incurabili” Hospital of Neaples Neaples, Italy

 

In order to treat arterial hypertension, we increased the dose of furosemide up to 100 mg/day, recommending the patient to check daily body weight and blood pressure; we also prescribed restriction in salt dietary intake. The specific recommendations for diuretic therapy were to progressively increase the dose of furosemide if body weight did not change, to reduce dosage of furosemide if daily decrease in body weight was greater than 0.5 kg; the goal of this therapy was to achieve a theoretical dry weight of 49-50 Kg. During the first two weeks the patient often called us to communicate the values of body weight and blood pressure in recumbent and standing posture in order to modify diuretic dosage that, accordingly, was increased up to 125 mg/day. After about 14 days the patient returned to our ambulatory; BP measures showed values of 130/80 mmHg in recumbent position and 110/70 after standing position; body weight was decreased of 4,0 kg; plasma creatinine and urea concentrations were 2.7 and 125 mg/dl, respectively.

Question 5