SUBJECT CONSULTANT REVIEW

Title of the article
Glomerular number and size in autopsy kidneys: The relationship to birth weight.
Authors
Hughson M, Farris AB, Douglas-Denton R, Hoy WE, Bertram JF.
Journal
Kidney Int. 2003 Jun;63(6):2113-22.
Subject Consultant
F. Mallamaci
Score (1 to 3 stars)
**
Cross referencing
 
Comments
Birth weight is a strong determinant of total glomerular number (Nglom) and thereby of glomerular size in the postnatal kidney. These findings support the hypothesis that low birth weight LBW by impairing nephron development is a risk factor for hypertension and ESRD in adulthood.