| Title
of the article |
Simvastatin normalizes autonomic neural control in experimental heart failure. |
| Authors |
Pliquett RU, Cornish KG, Peuler JD, Zucker IH. |
| Journal
|
Circulation. 2003 May 20;107(19):2493-8. |
| Subject
Consultant |
F. Mallamaci |
| Score
(1 to 3 stars) |
** |
| Cross
referencing |
Basic Science |
| Comments |
Non-lipid-lowering statin effects include a normalization of sympathetic outflow and reflex regulation in chronic heart failure (CHF). The precise neural and cellular pathways involved in these responses need further clarification. This finding may have important implications for the treatment of CHF and progression of the disease process. |
