| Title
of the article |
A low-carbohydrate as compared with a low-fat diet in severe obesity. |
| Authors |
Samaha FF, Iqbal N, Seshadri P, Chicano KL, Daily DA, McGrory J, Williams T, Williams M, Gracely EJ, Stern L. |
| Journal
|
N Engl J Med. 2003 May 22;348(21):2074-81. |
| Subject
Consultant |
F. Mallamaci |
| Score
(1 to 3 stars) |
*** |
| Cross
referencing |
|
| Comments |
Severely obese subjects with a high prevalence of diabetes or the metabolic syndrome lost more weight during six months on a carbohydrate-restricted diet than on a calorie- and fat-restricted diet, with a relative improvement in insulin sensitivity and triglyceride levels, even after adjustment for the amount of weight lost. Nevertheless future studies evaluating long-term cardiovascular outcomes are needed before a carbohydrate-restricted diet can be endorsed. |
