| Title
of the article |
Intrauterine exposure to maternal atherosclerotic risk factors increases the susceptibility to atherosclerosis in adult life. |
| Authors |
Alkemade FE, Gittenberger-de Groot AC, Schiel AE, Vanmunsteren JC, Hogers B, van Vliet LS, Poelmann RE, Havekes LM, Willems van Dijk K, Deruiter MC. |
| Journal
|
Arterioscler Thromb Vasc Biol. 2007 Oct;27(10):2228-35 |
| Subject
Consultant |
F. Mallamaci |
| Score
(1 to 3 stars) |
*** |
| Comments |
The susceptibility to neointima formation of morphologically normal adult arteries is already imprinted during prenatal development and manifests itself in the presence of additional atherogenic risk factors in adult life. Future research will concentrate on the mechanisms involved in this priming process, as well as on prevention strategies. |
