| Title
of the article |
Polymorphisms associated with cholesterol and risk of cardiovascular events |
| Authors |
Kathiresan S, Melander O, Anevski D, Guiducci C, Burtt NP, Roos C, Hirschhorn JN, Berglund G, Hedblad B, Groop L, Altshuler DM, Newton-Cheh C, Orho-Melander M |
| Journal
|
N Engl J Med. 2008 Mar 20;358(12):1240-9 |
| Subject
Consultant |
F. Mallamaci |
| Score
(1 to 3 stars) |
*** |
| Comments |
Common single-nucleotide polymorphisms (SNPs)was studied in 5414 subjects from the cardiovascular cohort of the Malmö Diet and Cancer Study.A genotype score of nine validated SNPs that are associated with modulation in levels of LDL or HDL cholesterol was an independent risk factor for incident cardiovascular disease. |
