| Title
of the article |
Pediatric antihypertensive trial failures: analysis of end points and dose range |
| Authors |
Benjamin DK Jr, Smith PB, Jadhav P, Gobburu JV, Murphy MD, Hasselblad V, Baker-Smith C, Califf RM, Li JS. |
| Journal
|
Hypertension. 2008 Apr;51(4):834-40 |
| Subject
Consultant |
F. Mallamaci |
| Score
(1 to 3 stars) |
*** |
| Comments |
The results of this critical analysis of antihypertensive pediatric trials, suggest that poor dose selection, lack of acknowledgement of differences between adult and pediatric populations, and lack of pediatric formulations are associated with failures of this kind of trials. |
