SUBJECT CONSULTANT REVIEW

Title of the article
Low birthweight is associated with narrower arterioles in adults.
Authors
Liew G, Wang JJ, Duncan BB, Klein R, Sharrett AR, Brancati F, Yeh HC, Mitchell P, Wong TY; Atherosclerosis Risk in Communities Study.
Journal
Hypertension. 2008 Apr;51(4):933-8.
Subject Consultant
F. Mallamaci
Score (1 to 3 stars)
***
Comments
Lower birthweight was associated with narrower retinal arteriolar caliber, after statistical adjustements for age, gender, race, education, smoking, alcohol consumption, adult body mass index, and height. These findings provide evidence that structural alterations in the arteriolar microcirculation may be a potential mechanism linking restricted fetal growth with subsequent risk of hypertension.