| Title
of the article |
Telmisartan, ramipril, or both in patients at high risk for vascular events |
| Authors |
ONTARGET Investigators, Yusuf S, Teo KK, Pogue J, Dyal L, Copland I, Schumacher H, Dagenais G, Sleight P, Anderson C. |
| Journal
|
N Engl J Med. 2008 Apr 10;358(15):1547-59 |
| Subject
Consultant |
F. Mallamaci |
| Score
(1 to 3 stars) |
*** |
| Comments |
Telmisartan was equivalent to ramipril in patients with vascular disease or high-risk diabetes and was associated with less angioedema. The combination of the two drugs was associated with more adverse events without an increase in benefit. |