SUBJECT CONSULTANT REVIEW

Title of the article
Use of ezetimibe in the United States and Canada
Authors
Jackevicius CA, Tu JV, Ross JS, Ko DT, Krumholz HM
Journal
N Engl J Med. 2008 Apr 24;358(17):1819-28
Subject Consultant
F. Mallamaci
Score (1 to 3 stars)
***
Comments
Distinct patterns of use of ezetimibe emerged in the United States and Canada from 2002 to 2006, a difference that markedly altered the approach to the treatment of hyperlipidemia in the United States. The U.S. pattern increased overall costs, but the effect on clinical outcomes is uncertain.