| Title
of the article |
Tadalafil therapy for pulmonary arterial hypertension. |
| Authors |
Galiè N, Brundage BH, Ghofrani HA, Oudiz RJ, Simonneau G, Safdar Z, Shapiro S, White RJ, Chan M, Beardsworth A, Frumkin L, Barst RJ; Pulmonary Arterial Hypertension and Response to Tadalafil (PHIRST) Study Group |
| Journal
|
Circulation. 2009 Jun 9;119(22):2894-903 |
| Subject
Consultant |
F. Mallamaci |
| Score
(1 to 3 stars) |
*** |
| Comments |
In this 16-week, double-blind, placebo-controlled study, 405 patients with pulmonary arterial hypertension (idiopathic or associated), tadalafil 40 mg was well tolerated and improved exercise capacity and quality of life measures and reduced clinical worsening. |
