SUBJECT CONSULTANT REVIEW

Title of the article
A randomized trial of therapies for type 2 diabetes and coronary artery disease.
Authors
BARI 2D Study Group, Frye RL, August P, Brooks MM, Hardison RM, Kelsey SF, MacGregor JM, Orchard TJ, Chaitman BR, Genuth SM, Goldberg SH, Hlatky MA, Jones TL, Molitch ME, Nesto RW, Sako EY, Sobel BE
Journal

N Engl J Med. 2009 Jun 11;360(24):2503-15

Subject Consultant
F. Mallamaci
Score (1 to 3 stars)
***
Comments
In this study 2368 patients with both type 2 diabetes and heart disease were randomly assigned to undergo either prompt revascularization with intensive medical therapy or intensive medical therapy alone and to undergo either insulin-sensitization or insulin-provision therapy. Overall, there was no significant difference in the rates of death and major cardiovascular events between patients undergoing prompt revascularization and those undergoing medical therapy or between strategies of insulin sensitization and insulin provision.