SUBJECT CONSULTANT REVIEW

Title of the article
Sustained appetite improvement in malnourished dialysis patients by daily ghrelin treatment.
Authors
Ashby DR, Ford HE, Wynne KJ, Wren AM, Murphy KG, Busbridge M, Brown EA, Taube DH, Ghatei MA, Tam FW, Bloom SR, Choi P.
Journal

Kidney Int. 2009 Jul;76(2):199-206

Subject Consultant
F. Mallamaci
Score (1 to 3 stars)
***
Comments
This study study shows that daily treatment with ghrelin achieves a sustained positive change in energy balance in malnourished dialysis patients. Direct manipulation of appetite with ghrelin or its analogs represents an attractive and promising therapeutic strategy for this difficult clinical problem.