EUROPEAN TRAINING CENTRES

Schloss Nymphenburg
Munich

 

Medizinische Poliklinik
University Clinic of Munich – Innenstadt
Nephrology Centre
Munich, Germany

Peer Reviewed Publications in International Journals (only English) 2000-2002

2000
1. Anders H.J, Rihl M., Loch O., Schattenkirchner M.: Prediction of creatinine clearance from serum creatinine in patients with rheumatoid arthritis: comparison of six formulae and one nomogram. Clin. Rheumatol. 26-29 (2000).
2. Berger T., Brigl M., Herrmann J.M., Vielhauer V., Luckow B., Schlöndorff D., Kretzler M.: MERM-3, a novel murine apoptosis mediator, localizes to the mitochondrial matrix. J. Cell Sci. 113: 3603-3612 (2000).
3. Böhlk S., Fessele S., Miyamoto N.G., Nelson E.L., Werner T., Schlöndorff D., Nelson P.J.: ATF and Jun transcription factors acting through an Ets/CRE transcription module mediate LPS inducibility of the chemokine RANTES in monocytic MonoMac 6 cells. Eur. J. Immunol. 30: 1102-1112 (2000).
4. Eitner F., Cui Y., Hudkins K.L., Stokes M.B., Segerer S., Mack M., Lewis P.L., Abraham A.A., Schlöndorff D., Gallo G., Kimmel P.L., Alpers C.E.: Chemokine receptor CCR5 and CXCR4 expression in HIV-associated kidney disease. J. Am. Soc. Nephrol. 11: 856-867 (2000).
5. Gencik M., Meller S., Borgmann S., Sitter T., Menezes Saecker A.M.,Fricke H.,Epplen. J.T.: The association of CD18 alleles with anti-myeloperoxidase subtypes of ANCA-associated vasculitides. Clin. Immun. 94: 9-12 (2000).
6. Haslinger B., Mandl-Weber S., Sitter T.: Thrombin suppresses matrix metallproteinase 2 activity and increases tissue inhibitor of metalloproteinase 1 synthesis in cultured human peritoneal mesothelial cells. Perit. Dial. Int. 20: 778-783 (2000).
7. Huber S.M., Braun G.S., Segerer S., Veh R.W., Horster M.F.: Metanephrogenic mesenchyme-to-epithelium transition induces profound expression changes of ion channels. Am. J. Physiol. Renal. Physiol. 279: F65-76. (2000).
8. Keuneke C., Rothenpieler U., Zanker B., Schneeberger H., Illner W.D., Theodorakis J., Stangl M., Land W.: Mycophenolate mofetil monotherapy: an example of a safe nephrotoxicity/atherogenicity-free immunosuppressive maintenance regimen in a selected group of kidney-transplanted patients. Transplant Proc. 32 (1A Suppl): 6S-8S (2000).
9. Lang S.M., Schiffl H.: Effect of dialyzer biocompatibility on recovery from acute renal failure after cadaveric renal transplantation. Nephrol. Dial. Transplant. 15: 134-35 (2000).
10. Luckow B., Maier H., Chilla S., Pérez de Lema G.: The mCK-5 multi-probe RNase protection assay kit can yield erroneous results for the murine chemokines IP-10 and MCP-1. Analyt. Biochem. 286: 193-197 (2000).
11. Mack M., Kleinschmidt A., Brühl H., Klier C., Nelson P.J., Cihak J., Plachy J., Stangassinger M., Erfle V., Schlöndorff D.: Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection. Nature Med. 6: 769-775 (2000).
12. Mack M.*, Elsner J.*, Brühl H., Dulkys Y., Kimmig D., Simmons G., Clapham P.R., Schlöndorff D., Kapp A., Wells T.N., Proudfoot A.E.: Differential activation of CC chemokine receptors by AOP-RANTES. J. Biol. Chem. 275: 7787-7794 (2000). *equal contribution
13. Mack M., Schlöndorff D.: Downmodulation and recycling of chemokine receptors. Methods Mol. Biol. 138: 191-195 (2000).
14. Miyamoto N.G., Medberry P.S., Böhlk S., Nelson P.J., Krensky A.M., Perez H.D.: Interleukin-1beta induction of the chemokine RANTES promoter in the human astrocytoma line CH235 requires both constitutive and inducible transcription factors. J. Neuroimmunol. 105: 78-90 (2000).
15. Pfirstinger J., Mack M.: Expression of chemokines in the periplasmic space of E. coli. Methods Mol. Biol. 138: 41-45 (2000).
16. Reiser J., Kriz W., Kretzler M., Mundel P.: The glomerular slit diaphragm is a modified adherens junction. J. Am. Soc. Nephrol. 11: 1-8 (2000).
17. Schmidt M., Burchardi C., SitterT., Held E., Schiffl H.: Procalcitonin in patients undergoing chronic hemodialysis. Nephron 84: 187-188 (2000).
18. Schulte R., Preger S., Fessele S, Nelson P.J., Autenrieth I.B.: Yersinia Enterocolitica invasion triggers IL-8 transcription by activation of Rel p65/p65 homodimers. FASEB J. 14: 1471-1484 (2000).
19. Segerer S., Cui Y., Hudkins K.L., Goodpaster T., Eitner F., Mack M., Schlöndorff D., Alpers C.E.: Expression of the chemokine monocyte chemoattractant protein-1 and its receptor chemokine receptor 2 in human crescentic glomerulonephritis. J. Am. Soc. Nephrol. 11: 2231-2242 (2000).
20. Segerer S., Regele H., Mack M., Kain R., Cartron J.P., Colin Y., Kerjaschki D., Schlöndorff D.: The Duffy antigen receptor for chemokines is up-regulated during acute renal transplant rejection and crescentic glomerulonephritis. Kidney Int. 58: 1546-1556 (2000).
21. Signoret N., Pelchen-Matthews A., Mack M., Proudfoot A.E., Marsh M.: Endocytosis and recycling of the HIV coreceptor CCR5. J. Cell Biol. 151: 1281-1294 (2000).
22. Steppich B., Dayyani F., Gruber R., Lorenz R., Mack M., Ziegler-Heitbrock H.W.: Selective mobilization of CD14(+)CD16(+) monocytes by exercise. Am. J. Physiol. Cell Physiol. 279: 578-586 (2000).
23. Toepfer M., Schroeder M., Müller-Felber W., Lochmüller H., Sitter T., Pongratz D., Schiffl H.: Successful management of polyneuropathy associated with IgM gammopathy of undetermined siginificance with antibody based immunoadsorption. Clin. Nephrol. 53: 404-407 (2000).
24. Tuma E., Eigler A.,Toepfer M., Endres S., Schiffl H.: Il-1 receptor antagonist production by isolated mononuclear cells is a better indicator of biocompatibility of hemodialysis membranes than that by stimulated whole blood. Nephron 86: 220-221 (2000).
25. Sitter T., Bergner A., Schiffl H.: Dialysate related cytokine induction and response to recombinant human erythropoietin in hemodialysis patients. Nephrol. Dial. Transplant. 15: 1207-1211 (2000).
26. Wang R., St. John P., Kretzler M., Wiggins R., Abrahamson D.: Molecular cloning, expression, and distribution of GLEPP1 in developing mouse kidney. Kidney Int. 57: 1847-1859 (2000).
27. Weber C., Belge K.U., von Hundelshausen P., Draude G., Steppich B., Mack M., Frankenberger M., Weber K.S., Ziegler-Heitbrock H.W.: Differential chemokine receptor expression and function in human monocyte subpopulations. J. Leukoc. Biol. 67: 699-704 (2000).


2001
1. Anders HJ, Vielhauer V, Kretzler M, Cohen CD, Segerer S, Luckow B, Weller L, Gröne HJ, Schlöndorff D (2001). Chemokine and chemokine receptor expression during initiation and resolution of immune complex glomerulonephritis. J Am Soc Nephrol. 12:919-31.
2. Anders HJ, Sigl T, Schattenkirchner M (2001) Primary or secondary raynaud`s phenomenon. A prospective study of nailfold capillaroscopy using an ophthalmoscope. Ann Rheum Dis. 60:407-9.
3. Banas, B, Eberle, J, Schlöndorff, D, Luckow, B (2001). Modulation of HIV-1 enhancer activity and virus production by cAMP. FEBS Lett. 509:207-12.
4. Blanpain C, Buser R, Power CA, Edgerton M, Buchanan C, Mack M, Simmons G, Clapham PR, Parmentier M, Proudfoot AE (2001) A chimeric MIP-1alpha/RANTES protein demonstrates the use of different regions of the RANTES protein to bind and activate its receptors. J Leukoc Biol. 69:977-985.
5. Borgmann S, Endisch G, Urban S, Sitter T, Fricke H (2001) A linkage disequilibrium between genes at the serine protease inhibitor gene cluster on chromosome 14q32.1 is associated with Wegener`s granulomatosis. Clin Immunol. 98: 244-248.
6. Brühl H, Wagner K, Kellner H, Schattenkirchner M, Schlondorff D, Mack M (2001) Surface expression of CC- and CXC-chemokine receptors on leucocyte subsets in inflammatory joint diseases. Clin Exp Immunol. 126:551-559.
7. Bruhl H, Wagner K, Kellner H, Schattenkirchner M, Schlondorff D, Mack M (2001) Surface expression of CC- and CXC-chemokine receptors on leucocyte subsets in inflammatory joint diseases. Clin Exp Immunol. 126:551-559.
8. Burkhardt K, Radespiel-Tröger M, Rupprecht HD, Riess R, Renders L, Hauser IA, Kunzendorf U (2001) An increase in myeloid related protein serum levels precedes acute renal allograft rejection. J. Am. Soc. Nephrol. 12:1947-1957.
9. Cohen CD, Keuneke C, Schiemann U, Schroppel B, Siegert S, Rascher W, Gross M, Schlondorff D (2001) Hyponatraemia as a complication of colonoscopy. Lancet. 27;357(9252):282-3.
10. Fessele S, Böhlk S, Miyamoto NG, Nelson EL, Werner T, Schlöndorff D and Nelson PJ (2001) Molecular and in silico Characterization of a Promoter Module and C/EBP Element that Regulate LPS Induced RANTES Expression in Monocytic cells. FASEB Journal 15: 577-579 10.1095/fj.01-0459fje.
11. Fischereder M, Luckow B, Hocher B, Wüthrich RP, Rothenpieler U, Schneeberger H, Panzer U, Stahl RA, Hauser IA, Budde K, Neumayer H, Kramer BK, Land W, Schlöndorff D (2001). CC chemokine receptor 5 and renal-transplant survival. Lancet. 357:1758-61. * shared first authorship
12. Goedde M, Grimbergen J, Toet K, Sitter T, Quax P, Kooistra T (2001) Adenovieus-mediated transfer of the 39-kD receptor-associated protein increases fibrinolytic capacity. Kidney Int 60: 117-125.
13. Goppelt-Struebe M, Hahn A, Iwanciw D, Rehm M, Banas B (2001) Regulation of connective tissue growth factor (ccn2; ctgf) gene expression in human mesangial cells: modulation by HMG CoA reductase inhibitors (statins) Mol Pathol. 54(3):176-9.
14. Haslinger B, Küchle C, Sitter T, Held E. (2001) Acute renal failure due to rhabdomyolysis in Mc Ardle´s disease following bige drinking with seizures. Dtsch Med Wochenschr 126: 1265-1268.
15. Haslinger B, Mandl-Weber S, Sellmayer A, Lederer SR, Sitter T (2001) Effect of high glucose concentration on the synthesis of monocyte chemoattractant protein-1 in human peritoneal mesothelial cells: involvement of protein kinase C. Nephron 87:346-351.
16. Horuk R, Clayberger C, Krensky AM, Wang Z, Gröne H-J, Weber C, Weber KSC, Nelson PJ, May K, Buckman B, Ghannam A, Ng HP, Islam I, Bauman JG, Wie GP, Monahan S, Xu W, Rosser M, Dunning L, Liang M, Snider RM, Morrissey MM, Hesselgesser J and Daniel Perez H (2001) Non-peptide Functional Antagonists of the CCR1 Chemokine Receptor are Effective in Rat Heart Transplant Rejection. Journal of Biological Chemistry. 276: 4199-4204.
17. Hudkins KL, Le QC, Segerer S, Johnson RJ, Davis CL, Giachelli CM, Alpers CE (2001) Osteopontin expression in human cyclosporine toxicity. Kidney Int. Aug;60(2):635-40.
18. Huo Y, Weber C, Forlow SB, Sperandio M, Thatte J, Mack M, Jung S, Littman DR, Ley K (2001) The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium. J Clin Invest. 108:1307-1314.
19. Jakobi J, Titze J, Niewerth P, Lang R, Schulze B, Rupprecht HD (2001) Severe hyponatriemia due to hypothalamic-pituitary adrenal insufficiency. Nephrol. Dial. Transplant. 16:1708-1710.
20. Haslinger B, Mandl-Weber S, Sellmayer A, Sitter T (2001) Hyaluronan fragments induce the synthesis of MCP-1 and IL-8 in cultured human peritoneal mesothelial cells. Cell Tissue Res 305: 79-86.
21. Klier C, Nelson EL, Cohen C, Horuk R, Schlöndorff D and Nelson PJ (2001) Chemokine-Induced Secretion of Gelatinase B in Primary Monocytes. Biological Chemistry 382: 1405-1410.
22. Kraft K, Olbrich H, Majoul I, Mack M, Proudfoot AE, Oppermann M (2001) Characterization of sequence determinants within the carboxyl-terminal domain of chemokine receptor CCR5 which regulate signaling and receptor internalization. J Biol Chem. 11:11.
23. Kretzler M, Holthoefer H, Teixeira VP, Unschuld G, Wanke R, Reiser J, Mundel P, Schlöndorff D (2001) Integrin linked kinase as a common downstream effector in failure of the glomerular filtration barrier. FASEB J, 15, 1843-5.
24. Kretzler M, Teixeira VPC, Berger T, Blattner SM, Cohen CD, Schlöndorff D (2001) Altering glomerular epithelial function in vitro using transient and stable transfection. J Nephrol, 14, 211-9.
25. Lederer SR, Kluth-Pepper B, Schneeberger H, Albert E, Land W, Feucht HE (2001) Impact of humoral alloreactivity early after transplantation on the long-term survival of renal allografts Kidney Int 59:334-341.
26. Mack M, Cihak J, Simonis C, Luckow B, Proudfoot AE, Plachy J, Brühl H, Frink M, Anders HJ, Vielhauer V, Pfirstinger J, Stangassinger M, Schlöndorff D (2001). Expression and characterization of the chemokine receptors CCR2 and CCR5 in mice. J Immunol. 166:4697-704.
27. Mandl-Weber S, Haslinger B, Lederer SR, Sitter T (2001) Heat-killed microorganisms induce PAI-1 expression in human peritoneal mesothelial cells: role of interleukin-1 alpha. Am J Kidney Dis 37:815-819.
28. Mandl-Weber S, Haslinger B, Schalkwijk CG, Sitter T (2001) Early glycated albumin but not advanced glycated albumin, methylglyoxal, or 3-Deoxyglucosone increases the expression of PAI-1 in human peritoneal mesothelial cells. Perit Dial Int 5: 487-494.
29. Perez de Lema, G, Maier, H, Nieto, E, Vielhauer, V, Luckow, B, Mampaso, F, Schlöndorff, D (2001). Chemokine expression precedes inflammatory cell infiltration and chemokine receptor and cytokine expression during the initiation of murine lupus nephritis. J Am Soc Nephrol. 12:1369-82..
30. Rupprecht HD, Ries R (2001) Acute myoglobinuric renal failure (Images in Clinical Medicine). New Engl. J. Med. 345:1747.
31. Schmidt M, Sitter T, Fricke H, Pfluger T, Held E (2001) Diffuse localized lesions of brain MRI in a 33 year old female with cognitive impairments. Internist 42: 743-774.
32. Schroppel B, Segerer S, Keuneke C, Cohen CD, Schlondorff D (2001) Hyponatremic encephalopathy after preparation for colonoscopy. Gastrointest Endosc. 53(4):527-9.
33. Taneda S, Segerer S, Hudkins KL, Cui Y, Wen M, Segerer M, Wener MH, Khairallah CG, Farr AG, Alpers CE (2001) Cryoglobulinemic glomerulonephritis in thymic stromal lymphopoietin transgenic mice. Am J Pathol. Dec;159(6):2355-69.
34. Tato F, Mack M, Meissner O, Schlondorff D (2001) A severe case of pneumatosis cystoides intestinalis with massive accumulation of gas outside the gastrointestinum. Z Gastroenterol. 39:797-800.
35. Vielhauer V*, Anders HJ*, Mack M, Cihak J, Strutz FM, Stangassinger M, Luckow B, Gröne HJ, Schlöndorff D (2001) Obstructive nephropathy in the mouse: progressive fibrosis correlates with tubulointerstitial chemokine expression and accumulation of CC chemokine receptor 2 and 5 positive leukocytes. J Am Soc Nephrol. 12:1173-87.
36. von Hundelshausen P, Weber KSC, Huo Y, Proudfoot AEI, Nelson PJ, Ley K and Weber C (2001) RANTES Deposition by Platelets Triggers Monocyte Arrest on Inflamed Endothelium: Implications for Recruitment to Atherosclerotic Lesions. Circulation 103: 1772-1777.
37. Wagner, K, Dendorfer, U, Chilla, S, Schlöndorff, D, Luckow, B (2001). Identification of new regulatory sequences far upstream of the mouse monocyte chemoattractant protein-1 gene. Genomics. 78:113-23.
38. Weber C, Weber KSC, Horuk R, Wank R, Hi S, Klier CM and Nelson JP (2001) Specialized roles of the Chemokine Receptors CCR1 and CCR5 in Recruitment of Monocytes and Th1 T cells. Blood 97: 1144-1146.
39. Weber KSC, Gröne H-J, Klier C, Gu S, Wank R, Proudfoot AEI, Nelson PJ, and Weber C (2001) Viral MIP-II Chemokine Shifts Leukocyte Recruitment in Shear Flow from a Th1/Monocyte towards a Th2/Eosinophil Response. European Journal of Immunology 31: 2458-2466.
40. Weidner S, Neupert W, Goppelt-Strübe M, Rupprecht HD (2001) Antineutrophilic cytoplasmic antibodies induce human monocytes to produce oxygen radicals in vitro. Arthritis and Rheumat. 44 :1698-1706.


2002
1. Anders HJ, Vielhauer V, Frink M, Linde Y, Cohen CD, Blattner SM, Kretzler M, Strutz F, Mack M, Grone HJ, Onuffer J, Horuk R, Nelson PJ, Schlondorff D (2002) A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation. J Clin Invest. 2002 Jan;109(2):251-9.
2. Banas B, Wörnle M, Berger T, Nelson PJ, Cohen CD, Kretzler M, Pfirstinger J, Mack M, Lipp M, Grone HJ, Schlondorff D (2002) Roles of SLC/CCL21 and CCR7 in human kidney for mesangial proliferation, migration, apoptosis, and tissue homeostasis. J Immunol. 2002 May 1,168(9):4301-7.
3. Berger T, Kretzler M (2002) TRAIL-induced apoptosis is independent of the mitochondrial apoptosis mediator DAP3. Biochem Biophys Res Commun. 2002 Oct 4;297(4).880.
4. Berger T, Kretzler M (2002) Interaction of DAP3 and FADd only after cellular disruption. Nat Immunol. 2002 Jan;3(1):3-5.
5. Blanpain C, Vanderwinden JM, Cihak J, Wittamer V, Le Poul E, Issafras H, Stangassinger M, Vassart G, Marullo S, Schlondorff D, Parmentier M,Mack M (2002) Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies. Mol Biol Cell. 2002 Feb;13(2):723-37.
6. Cohen CD, Kretzler M (2002) Gene Expression Analysis in Microdissected Renal Tissue. Current challenges and strategies. Nephron 2002 Nov;92(3):522-8.
7. Cohen CD, Frach K, Schlondorff D, Kretzler M (2002) Quantitative gene expression analysis in renal biopsies: a novel protocol for a high-throughput multicenter application. Kidney Int. 2002 Jan;61(1):133-40.
8. Cohen CD, Grone HJ, Grone EF, Nelson PJ, Schlondorff D, Kretzler M (2002) Laser microdissection and gene expression analysis on formaldehyde-ficed archival tissue. Kidney Int. 2002 Jan;61(1):125-32.
9. Delles C, Weidner S, Schobel HP, Rupprecht HD (2002) Renal-artery stenosis in a patient with Takayasu´s arteritis. Nephrol Dial Transplant. 2002 Jul;17(7):1339-41.
10. Delles C, Wittmann M, Renders L, Kunzendorf U, Bohner C, Wutke R, Lang W, Schott GE, Rupprecht HD (2002) Restoration of renal allograft function by endovascular stenting of an iliac artery dissection. Nephrol Dial Transplant. 2002 Jun;17(6):1116-8.
11. Ernst T, Hergenhahn M, Kenzelmann M, Cohen CD, Bonrouhi M, Weninger A, Klaren R, Grone EF, Wiesel M, Gudemann C, Kuster J, Schott W, Staehler G, Kretzler M, Hollstein M, Grone HJ (2002) Decrease and gain of gene expression are equally discriminatory markers for prostate carcinoma: a gene expression analysis on total and microdissected prostate tissue. Am j Pathol. 2002 Jun;160(6):2169-80.
12. Fessele S, Maier H, Zischek C, Nelson PJ, Werner T (2002) Regulatory context is a crucial part of gene function. Trends Genet. 2002 Feb;18(2):60-3.
13. Fischer KG, Jonas N, Poschenrieder F, Cohen C, Kretzler M, Greiber S, Pavenstadt H (2002) Characterization of a Na(+)-Ca(2+) exchanger in podocytes. Nephrol Dial Transplant. 2002 Oct;17(10):1742-50.
14. Grone HJ, Cohen CD, Grone E, Schmidt C, Kretzler M, Schlondorff D, Nelson PJ (2002) Spatial and temporally restricted expression of chemokines and chemokine receptors in the developing human kidney. J Am Soc Nephrol. 2002 Apr;13(4):957-67.
15. Haslinger B, Goedde MF, Toet KH, Kooistra T (2002) Simvastatin increases fibrinolytic activity in human peritoneal mesothelial cells independent of cholesterol lowering. Kidney Int. 2002 Nov;62(5):1611-9.
16. Keil A, Blom IE, Goldschmeding R, Rupprecht HD (2002) Nitric oxide down-regulates connective tissue growth factor in rat mesangial cells. Kidney Int. 2002 Aug;62(2):401-11.
17. Kretzler M, Cohen CD, Doran P, Henger A, Madden S, Grone EF, Nelson PJ, Schlondorff D, Grone HJ (2002) Repuncturing the renal biopsy: strategies for molecular diagnosis in nephrology. J Am Soc Nephrol. 2002 Jul;13(7):1961-72.
18. Kretzler M (2002) Regulation of adhesive interaction between podocytes and glomerular basement membrane. Microsc Res Tech. 2002 May 15;57(4):247-53.
19. Mack M, Pfirstinger J, Weber C, Weber KS, Nelson PJ, Rupp T, Maletz K, Bruhl H, Schlondorff D (2002) Chondroitin sulfate A released from platelets blocks RANTES presentation on cell surfaces and RANTES-dependent firm adhesion of leukocytes. Eur J Immunol.2002 Apr;32(4):1012-20.
20. Mandl-Weber S, Cohen CD, Haslinger B, Kretzler M, Sitter T (2002) Vascular endothelial growth factor production and regulation in human peritoneal mesothelial cells. Kidney Int. 2002 Feb;61(2):570-8.
21. Maus U, von Grote K, Kuziel WA, Mack M, Miller EJ, Cihak J, Stangassinger M, Maus R, Schlondorff D, Seeger W, Lohmeyer J (2002) The role of CC chemokine receptor 2 in alveolar monocyte and neutrophil immigration in intact mice. Am J Respir Crit Care Med. 2002 Aug 1;166(3):268-73.
22. Maus UA, Koay MA, Delbeck T, Mack m, Ermert M, Ermert L, Blackwell TS, Christman JW, Schlondorff D, Seeger W, Lohmeyer J (2002) Role of resident alveolar macrophages in leukocyte traffic into the alveolar air space of intact mice. Am J Physiol Lung Cell Mol Physiol. 2002 Jun;282(6):L1245-52.
23. Nakamura H, Isaka Y, Tsujie M, Rupprecht HD, Akagi Y, Ueda N, Imai E, Hori M (2002) Introduction of DANN enzyme for Egr-1 into tubulointerstitial fibroblasts by electroporation reduced interstitial alpha-smooth muscle actin expression and fibrosis in unilateral ureteral obstruction (UUO) rats. Gene Ther. 2002 Apr;9(8):495-502.
24. Nelson PJ, Sunamoto M, Husain M, Gelman IH (2002) HIV-1 expression induces cyclin D1 expression and pRb phosphorylation in infected podocytes: cell-cycle mechanismus contributing to the proliferative phenotype in HIV-associated nephropathy. BMC Microbiol. 2002 Sept 19;2(1):26.
25. Nelson PJ, Daniel TO (2002) Emerging targets: Molecular mechanisms of cell contact-mediated growth control. Kidney Int. 2002 Jan;61 Suppl 1:99-105.
26. Rieger J, Sitter T, Toepfer M, Linsenmaier U, Pfeifer KJ, Schiffl H (2002) Gadolinium as an alternative contrast agent for diagnostic and interventional angiographic procedures in patients with impaired renal function. Nephrol Dial Transplant. 2002 May;17(5):824-8.
27. Segerer S, Hughes E, Hudkins KL, Mack M, Goodpaster T, Alpers CE (2002) Expression of the fractalkine receptor (CX3CR1) in human kidney diseases. Kidney Int. 2002 Aug;62(2):488-95.
28. Segerer S, Hudkins KL, Taneda S, Wen M, Cui Y, Segerer M, Farr AG Alpers CE (2002) Oral interferon-alpha treatment of mice with cryoglobulinemic glomerulonephritis. Am J Kidney Dis. 2002 Apr;39(4):876-88.
29. Segerer S, Eitner F, Cui Y, Hudkins KL, Alpers CE (2002) Cellular injury associated with renal thrombotic microangiopathy in human immunodeficiency virus-infected macaques. J Am Soc Nephrol. 2002 Feb;13(2):370-8.
30. Sitter T, Schmidt M, Schneider S, Schiffl H (2002) Differential diagnosis of bacterial infection and inflammatory response in kidney diseases using procalcitonin. J Nephrol. 2002 May-Jun;15(3):297-301.
31. Wen M, Segerer S, Dantas M, Brown PA, Hudkins KL, Goodpaster T, Kirk E, LeBoeuf RC, Alpers CE (2002) Renal injury in apolipoprotein E-deficient mice. Lab Invest. 2002 Aug;82(8):999-1006.

2003

  1. Anders HJ, Banas B, Linde Y, Weller L, Cohen CD, Kretzler M, Martin S, Vielhauer V, Schlöndorff D, Gröne HJ. (2003) Bacterial CpG-DNA aggravates immune complex glomerulonephritis: role of TLR9-mediated expression of chemokines and chemokine receptors. J Am Soc Nephrol. 14: 317-26. IF 6,4
  2. Anders HJ, Vielhauer V, Schlöndorff D. (2003) Chemokines and chemokine receptors are involved in the resolution or progression of renal disease. Kidney Int 63: 401-15. IF 4,4
  3. Anders HJ, Frink M, Linde Y, Banas B, Wörnle M, Cohen CD, Vielhauer V, Nelson PJ, Gröne HJ, Schlöndorff D. (2003) CC chemokine ligand 5/RANTES chemokine antagonists aggravate glomerulonephritis despite reduction of glomerular leukocyte infiltration. J Immunol 170:5658-66. IF 7,3
  4. Anders HJ, Frink M, Linde Y Veilhaouer V, Cohen CD, Banas B, Wörnle M, Nelson PJ, Gröne HJ, Schlöndorff D (2003) CC Chemokine Ligand 5/RANTES Chemokine Antagonists Aggravate Glomerulonephritis Despite Reduction of Glomerular Leukocyte Infiltration.  J Immunol 170: 5658-5666 IF: 7.014
  5. Brühl H, Cohen C, Linder S, Kretzler M, Schlöndorff D, Mack M (2003) Post-translational and cell type-specific regulation of CXCR4 expression by cytokines. Eur J Immunol. 33:3028–3037. IF: 5,2
  6. Carl M, Akagi Y, Weidner S, Isaka Y, Imai E, Rupprecht HD (2003): Specific inhibition of Egr-1 prevents mesangial cell hypercellularity in experimental nephritis.Kidney International 63, 1302-1312  IF 5,0
  7. Fischereder M, Schröppel B, Wiese P, Fink M, Banas B, Schmidbauer S, Schlöndorff D (2003) Regulation of glucose transporters in human peritoneal mesothelial cells. J Nephrol 16:103-109  IF 0,971
  8. Lederer SR, Friedrich N, Regenbogen C, Getto R, Toepfer M, Sitter T (2003) Non-invasive monitoring of renal transplant recipients: urinary excretion of soluble adhesion molecules and of the complement-split product C4d. Nephron Clin Pract 94:c19-26
  9. Pérez de Lema G, de Wit C, Cohen CD, Nieto E, Molina A, Banas B, Luckow B, Vicente AB, Mampaso F, Schlöndorff D (2003) Angiotensin inhibition reduces glomerular damage and renal chemokine expression in MRL/lpr mice. J Pharmacol Exp Ther 307:275-281  IF 3,991
  10. Schmid H, Henger A, Cohen CD, Frach K, Gröne HJ, Schlöndorff D, Kretzler M (2003) Gene expression profiles of podocyte-associated molecules as diagnostic markers in acquired proteinuric disease. J Am Soc Nephrol 14: 2958-2966 (IF 6.4)
  11. Schmid H, Cohen CD, Henger A, Irrgang S, Schlöndorff D, Kretzler M  (2003)Validation of endogenous controls for gene expression analysis in microdissected human renal biopsies. Kidney Int 64: 356-360 (IF 5.0)
  12. Segerer S, GA Böhmig, M Exner, Y. Colin, JP Cartron, D. Kerjaschki, D. Schlöndorff, H. Regele (2003) When renal allografts turn darc. Transplantation 75:1030-1034  IF 4,0
  13. Sitter T, Sauter M, Haslinger B (2003) Modulation of fibrinolytic sysrtem components in mesothelial cells by hyaluronan. Perit Dial Int 23:222-227  IF 1,7
  14. Taneda S, KL Hudkins, Y Cui, AG Farr, CE Alpers, Segerer S (2003) Growth factor expression in a murine model of cryoglobulinemia. Kidney International 63: 576-590 IF 4,8
  15. Vielhauer V, Anders HJ, Perez de Lema G, Luckow B, Schlöndorff D, Mack M (2003) Phenotyping renal leukocyte subsets by four-color flow cytometry: characterization of chemokine receptor expression. Nephron Exp Nephrol. 93:63-71. IF:1,8
  16. Werner T, Fessele S, Maier H, Nelson PJ (2003)  Computer Modeling of Promoter Organization as a Tool to Study Transcriptional Co-Regulation. FASEB J 17: 1228-1237  IF: 7.252

 

2004

  1. Anders HJ, Vielhauer V, Eis V, Linde Y, Kretzler M, Perez de Lema G, Strutz F, Bauer S, Rutz M, Wagner H, Gröne HJ, Schlöndorff D (2004). Activation of Toll-like receptor-9 induces progression of renal disease in MRL(Fas)lpr mice. FASEB J. 18:534-6. IF 7.2
  2. Anders HJ, Belemezova E, Eis V, Segerer S, Perez de Lema G, Kretzler M, Cohen CD, Vielhauer V, Horuk R, Hudkins KL, Alpers CE, Mampaso F, Schlöndorff D. (2004) Late onset of treatment with a chemokine receptor CCR1 antagonist prevents progression of lupus nephritis in MRL(Fas)lpr mice. J Am Soc Nephrol 2004, 15:1504-1513. IF 7.5
  3. Banas B, Wörnle M, Merkle M, Gonzalez-Rubio M, Schmid H, Kretzler M, Pietrzyk MC, Fink M, Perez de Lema G, Schlöndorff D. (2004) Binding of the chemokine SLC/CCL21 to its receptor CCR7 increases adhesive properties of human mesangial cells. Kidney Int 66(6):2256-63. IF 5.3
  4. Djafarzadeh R, A. Mojaat A, von Lüttichau I, Nelson PJ. (2004) Exogenously added GPI Anchored Tissue Inhibitor of Matrix Metalloproteinase-1 (TIMP-1) Displays Novel and Enhanced Biologic Activity. Biol Chem. 385:655-663. IF 3.366
  5. Eis V, Luckow B, Vielhauer V, Siveke J, Mack M, Horuk R, Murphy PM, Gröne HJ, Schlöndorff D, Anders HJ (2004) Chemokine receptor CCR1 but CCR5 mediates leukocyte recruitment and subsequent renal fibrosis after unilateral ureteral obstruction. J Am Soc Nephrol. 15:337-347. IF 7.5
  6. Elvin SJ, Williamson ED, Scott JC, Smith JN, Perez De Lema G, Chilla S, Clapham P, Pfeffer K, Schlöndorff D, Luckow B. (2004) Evolutionary genetics: Ambiguous role of CCR5 in Y. pestis infection. Nature. 430(6998):1 p following 417. IF 31
  7. Henger A, Kretzler M, Doran P, Bonrouhi M, Schmid H, Kiss E, Cohen CD, Madden S, Porubsky S, Gröne EF, Schlöndorff D, Nelson PJ, Gröne HJ. (2004) Gene expression fingerprints in human tubulo-interstitial inflammation and fibrosis as prognostic markers of disease progression. Kidney Int, 65, 904-17. IF 5.302
  8. Luckow B, Joergensen J, Chilla S, Li JP, Henger A, Kiss E, Wieczorek G, Roth L, Hartmann N, Hoffmann R, Kretzler M, Nelson PJ, de Lema GP, Maier H, Wurst W, Balling R, Pfeffer K, Gröne HJ, Schlöndorff D, Zerwes HG. (2004) Reduced intragraft mRNA expression of metalloproteinases Mmp3, Mmp12, Mmp13, Adam8 and diminished transplant arteriosclerosis in Ccr5-deficient mice. Eur J Immunol. 34:2568-78. IF 4.536
  9. Perez de Lema G, Lucio-Cazana FJ, Molina A, Luckow B, Schmid H, de Wit C, Moreno-Manzano V, Banas B, Mampaso F, Schlöndorff D. (2004) Retinoic acid treatment protects MRL/lpr lupus mice from the development of glomerular disease. Kidney Int. 66(3):1018-28. IF 5.302
  10. Porubsky S, Schmid H, Bonrouhi M, Kretzler M, Malle E, Nelson PJ, Groene HJ. (2004) Influence of native and hypochlorite-modified low-density lipoprotein on gene expression in human proximal tubular epithelium. Am J Path. 164:2175-2187.  IF 6.046
  11. Pietrzyk MC, Banas B, Wolf K, Rümmele P, Woenckhaus M, Hoffmann U, Krämer BK, Fischereder M. (2004) Quantitative gene expression analysis of fractalkine using laser microdissection in biopsies from kidney allografts with acute rejection. Transplant Proc. 36:2659-61. IF 0.588
  12. Segerer S, Banas B, Wörnle M, Schmid H, Cohen C, Kretzler M, Mack M, Kiss E, Nelson PJ, Schlöndorff D, Gröne HJ. (2004) CXCR3 is involved in tubulointerstitial injury in human glomerulonephritis. Am J Path. 164:635-49. IF 6.046
  13. Vielhauer V, Berning E, Eis V, Kretzler M, Strutz F, Horuk R, Gröne HJ, Schlöndorff D, Anders HJ. (2004) CC-Chemokine receptor-1 blockade reduces interstitial fibrosis in mice with focal segmental glomerular sclerosis and nephrotic syndrome. Kidney Int. 66:2264-78. IF 5.302
  14. Weidner S, Carl M, Riess R, Rupprecht HD. (2004) Histological analysis of renal leukocyte infiltration in ANCA-associated vascuitis – importance of monocyte and neutrophil infiltration for tissue damage. Arthritis Rheum. 50:3651-3657 IF 7,19
  15. Weidner S, Geuss S, Hafezi-RachtiS, Wonka A, Rupprecht HD. (2004) ANCA-associated vasculitis with renal involvement: an outcome analysis. Nephrol Dial Transplant. 19:1403-11. IF 2,607
  16. Wörnle M, Schmid H, Merkle M, Banas B. (2004) Effects of chemokines on proliferation and apoptosis of human mesangial cells. BMC Nephrol 20;5(1):8. 
  17. Wörnle M, Angstwurm MW, SitterT. (2004) Treatment of intoxication with Cortinarius speciosissimus using an antioxidant therapy. Am J Kidney Dis. 43:e3-6. IF 3.8


2005

  1. Anders HJ, Ninichuk V, Schlöndorff D. (2005) Progression of kidney disease: blocking leukocyte recruitment with chemokine receptor CCR1 antagonists. Kidney Int, in press. IF 5.3
  2. Anders HJ, Patole PS. (2005) Toll-like receptors recognize uropathogenic Escherichia coli and trigger inflammation in the urinary tract. Nephrol Dial Transplant 20:1529-32. IF 2.607
  3. Argirov M, Ricken G, Zecher D, Fischereder M. (2005) Acute interstitial nephritis associated with moxifloxacin use. Clin Ther. 27(8):1260-3. IF 3.009
  4. Brühl H, Vielhauer V, Weiss M, Mack M, Schlöndorff D, Segerer S. (2005) Expression of DARC, CXCR3 and CCR5 in giant cell arteritis. Rheumatology. 44(3):309-13. IF 3.7
  5. Cohen CD, Calvaresi N, Armelloni S, Schmid H, Henger A, Ott U, Rastaldi MP, Kretzler M. (2005) CD20-positive infiltrates in human membranous glomerulonephritis. J Nephrol. 18(3):328-33. IF 1.025
  6. Cohen CD, Doran PP, Blattner SM, Merkle M, Wang GQ, Schmid H, Mathieson PW, Saleem MA, Henger A, Rastaldi MP, Kretzler M. (2005) Sam68-like mammalian protein 2, identified by digital differential display as expressed by podocytes, is induced in proteinuria and involved in splice site selection of vascular endothelial growth factor. J Am Soc Nephrol. 16(7):1958-65. IF 7.499
  7. Fischereder M, Jauch KW. (2005) Prevalence of cancer history prior to renal transplantation. Transplant Int. 18(7):779-84. IF 1.204
  8. Lederer SR, Friedrich N, Banas B, Welser G, Albert ED, Sitter T. (2005) Effects of mycophenolate mofetil on donor-specific antibody formation in renal transplantation. Clin Transplant. 19(2):168-74. IF 1.635
  9. Luttichaux IV, Notohamiprodjo M, Wechselberger A, Peters C, Henger A, Seliger C, Djafarzadeh R, Huss R, Nelson PJ. (2005) Human adult CD34- progenitor cells functionally express the chemokine receptors CCR1, CCR4, CCR7, CXCR5, and CCR10 but not CXCR4. Stem Cells Dev. 14(3):329-36.
  10. Merkle M, Wornle M, Rupprecht HD. (2005) The effect of sevelamer on tacrolimus target levels. Transplantation. 80(5):707. IF 3.568
  11. Ninichuk V, Gross O, Reichel C, Khandoga A, Ciubar R, Segerer S, Belemezova E, Radomska E, Luckow B, Perez de Lema G, Murphy PM, Gao JL, Henger A, Kretzler M, Horuk R, Weber M, Krombach F, Schlöndorff D, Anders HJ (2005) Delayed chemokine receptor CCR-1 blockade prolongs survival in collagen-4A3-deficient mice with Alport disease. J Am Soc Nephrol, 16:977-985. IF 7.499
  12. Ninichuk V, Gross O, Reichel C, Khandoga A, Ciubar R, Segerer S, Belemezova E, Radomska E, Luckow B, Perez de Lema G, Murphy PM, Gao JL, Henger A, Kretzler M, Horuk R, Weber M, Krombach F, Schlöndorff D, Anders HJ. (2005) Delayed chemokine receptor CCR-1 blockade prolongs survival in collagen-4A3-deficient mice with Alport disease. J Am Soc Nephrol. in press. IF 7.499
  13. Notohamiprodjo M, Hildebrandt B, Buck W, Huss R, Segerer S, Kretzler M, Henger A, Nelson PJ, von Lüttichau I. (2005) CCR10 is expressed in Cutaneous T-cell Lymphoma. Int J Cancer. 115(4):641-7. IF 4.375
  14. Patole P, Gröne HJ, Segerer S, Ciubar R, Belemezova E, Henger A, Kretzler M, Schlöndorff D, Anders HJ (2005) Viral double-stranded RNA aggravates lupus nephritis through Toll-like receptor–3 on glomerular mesangial cells and antigen-presenting cells.  J Am Soc Nephrol 16:1326-38. IF 7.499
  15. Patole P, Segerer S, Schubert S, Meßmer A. Henger A, Kretzler M, Werner M, Schlöndorff D, Anders HJ (2005) Toll-like receptor-4 on both renal cells and bone marrow-derived cells signals for neutrophil recruitment during infective pyelonephritis. Kidney Int, in press. IF 5.302
  16. Patole P, Zecher D, Pawar RD, Schlöndorff D, Anders HJ. (2005)Lupus nephritis suppressed by G-rich DNA. J Am Soc Nephrol, 21. (Epub ahead of print). IF 7.499
  17. Pawar RD, Patole PS, Zecher D, Kretzler M, Schlöndorff D, Anders HJ (2005) Toll-like receptor-7 modulates immune complex glomerulonephritis.  J Am Soc Nephrol, in press. IF 7.499
  18. Schmid H, Burg M, Kretzler M, Banas B, Grone HJ, Kliem V. (2005) BK virus associated nephropathy in native kidneys of a heart allograft recipient. Am J Transplant. 5(6):1562-8. IF 5.306
  19. Schmid H, Nitschko H, Gerth J, Kliem V, Henger A, Cohen CD, Schlondorff D, Grone HJ, Kretzler M. (2005) Polyomavirus DNA and RNA Detection in Renal Allograft Biopsies: Results from a European Multicenter Study. Transplantation. 80(5):600-604. IF 3.568
  20. Segerer S, Bohmig GA, Exner M, Kerjaschki D, Regele H, Schlondorff D. (2005) Role of CXCR3 in cellular but not humoral renal allograft rejection. Transpl Int. 18(6):676-80. IF 1.204
  21. Sitter T, Sauter M. (2005) Impact of glucose in peritoneal dialysis: saint or sinner? Perit Dial Int. 25(5):415-25. IF 1.056
  22. Teixeira VPC, Blattner SM, Li M, Anders HJ, Cohen CD, Calvaresi N, Edenhofer I, Merkle M, Rastaldi MP, Kretzler M (2005) Functional consequences of integrin-linked kinase activation in podocyte damage. Kidney Int. 67: 514-23. IF 5.302
  23. Vielhauer V, Stavrakis G, Mayadas TN. (2005) Renal cell-expressed TNF receptor 2, not receptor 1, is essential for the development of glomerulonephritis. J Clin Invest. 115(5):1199-209. IF 14.204