SUBJECT CONSULTANT REVIEW

Title of the article
Urinary CD80 is elevated in minimal change disease but not in focal segmental glomerulosclerosis.
Authors

Garin EH, Mu W, Arthur JM, Rivard CJ, Araya CE, Shimada M, Johnson RJ.

Journal
Kidney Int. 2010 Aug;78(3):296-302. Epub 2010 May 19.
Subject Consultant
V. Nickeleit
Score (1 to 3 stars)
*
Comments
Interesting pilot study suggesting that CD80 (B7.1) is expressed in podocytes of patients with "active/relapsing" minimal change disease (and secreted into the urine) but not in patients with FSGS or MCD in remission. Clearly further comprehensive studies are need - but maybe CD80 is a marker for MCD....