Editorial issue 292

Let me start this editorial with a landmark paper. M. Verbitsky et al. recently published in the JCI  “Genomic imbalances in pediatric patients with chronic kidney disease”. The authors (the group of Ali G. Gharavi), using the microarray technology, identified diagnostic copy number disorders in 31 children with CKD (7.4% of the cohort). These genetic disorders were largely unsuspected prior to the use of this technology.
In the next paper, recently published in NDT, M Betjes et al. show that “Encapsulating peritoneal sclerosis is associated with T-cell activation”.
In the third paper, G. Kotroumbas et al., again in NDT, show that “Ambulatory aortic blood pressure, wave reflections and pulse wave velocity are elevated during the third in comparison to the second interdialytic day of the long interval in chronic haemodialysis patients”.
In the 4th paper, Peter Stenvinkel et al. publish in NDT too a  review entitled “Muscle wasting in end-stage renal disease promulgates premature death: established, emerging and potential novel treatment strategies”.
Finally, in the last paper, Carlo Lomonte and Carlo Basile review in the Clinical Kidney Journal (CKJ) “Preoperative assessment and planning of haemodialysis vascular access”.

CME lectures

The 3 CME lectures of this issue of NDT-E start with the talk by Dr M Betjes (Rotterdam, The Netherlands). He deals with “Encapsulating peritoneal sclerosis “. The talk covers from diagnosis to  epidemiology and management.
The next speaker is Prof. Fr. Mallamaci (Reggio di Calabria, Italy) who covers “Pulmonary congestion as the key alteration in heart failure and in ESKD”.
Lastly, Prof. A. Wiecek (Katowice, Poland) discusses “ Pros and cons of lipid lowering therapy in CKD: when, how and whom?"

Enjoy NDT-Edu!

Prof. Michel Jadoul
Editor-in-Chief NDT-Educational