Editorial issue 317

This 317th issue of NDT-E starts with a paper dealing with an issue sometimes faced by nephrologists and their patients. Indeed, in a recent JCI paper, Eleftheria Lefkou et al report that Pravastatin improves pregnancy outcomes in obstetric antiphospholipid syndrome refractory to antithrombotic therapy. The study size was small but the results convinced the JCI editor and may offer, especially if confirmed, a new hope in this sometimes devastating condition.
The next 4 papers were all recently published in NDT. Rajiv Agarwal firstly publishes a study devoted to "Arterial stiffness and its relationship to clinic and ambulatory blood pressure: a longitudinal study in non-dialysis chronic kidney disease". Next, Kathryn K. Stevens et al. report on the  "Deleterious effects of phosphate on vascular and endothelial function via disruption to the nitric oxide pathway".
Then,  Émilie René et al. report on  the 2Association of erythropoiesis-stimulating agents and the incidence risk of cancer diagnosis among chronic dialysis patients: a nested case–control study".
And finally, Hendrica Belge et al. describe the "Clinical and mutational spectrum of hypoparathyroidism, deafness and renal dysplasia syndrome".

CME lectures   
The 4 CME Lectures released with this issue all were presented at ERA-EDTA 2015, in London.
Prof Raymond Vanholder (Ghent, Belgium), first discusses "Uremic toxin profile in AKI versus CKD: any therapeutic implications?".
Next , Prof. Maarten Naesens (Leuven, Belgium) presents "Emerging factors for predicting adverse outcomes in kidney transplantation: more pieces to the puzzle?".
Then, Prof Pieter Evenepoel (Leuven, Belgium) discusses a hot topic "Uremic toxins and gut".
Finally, Dr Jean-Marc Chillon (Amiens, France) overviews "Uremic toxins and neurologic outcomes".

Enjoy NDT-E. Wish you also some good, quiet time this summer

Prof. Michel Jadoul
Editor-in-Chief NDT-Educational