Editorial issue 241

Take the opportunity to learn more about renal replacement therapy in sepsis


In the 241th issue of NDT-E you will find four CME lectures presented at the ERA-EDTA meeting in Paris May 2012. Dr. Eric Hoste, Ghent, Belgium will present a lecture entitled “GENERAL, NON-RENAL MANAGEMENT OF SEPTIC SHOCK”. The 2nd lecture is entitled ”DIAGNOSIS AND TREATMENT OF HYPONATREMIA IN THE ICU -THE ERBP GUIDELINE” and is presented by Dr. Evi Nagler, also from Ghent, Belgium. Prof Achim Jörres from Berlin, Germany will in his lecture with the title ”SLED VS CRRT VS IHD IN SEPSIS” discuss acute renal replacement therapy in sepsis. The final CME lecture is presented by Dr. Heleen M. Oudemans-van Straaten, Amsterdam, Netherlands and is entitled ”CRRT IN SEPSIS, DOES THE ANTICOGULANT MATTER?


In the 241th issue of NDT-E you will also find several novel interesting papers to read. In a paper recently published in Kidney International, Shokei Kim-Mitsuyama et al. present the OSCAR study which was a multicenter, prospective randomized open-label blinded end-point study of 1164 Japanese elderly hypertensive patients comparing the efficacy of angiotensin II receptor blocker (ARB) uptitration to an ARB plus calcium channel blocker (CCB) combination. The results show that the ARB plus CCB combination conferred greater benefit in prevention of cardiovascular events in patients with CKD compared with high-dose ARB alone. You will also be able to read the report on 2012 ISN Nexus Symposium: ‘Bone and the Kidney’ by Tilman Drüeke and Klaus Olgaard. In a 3rd Kidney Int paper Hiroshi Watanabe et al. will show that p-Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase. In a recent paper published in NDT Dr. Salvatore De Cosmo et al. discuss the role of insulin resistance and related abnormalities on kidney dysfunction. In another NDT paper Dr. Giuseppe Regolisti et al. show data that suggest that acute kidney injury patients may be more vulnerable than ESRD patients to cerebral hypoperfusion during IHD. Finally, in an article published in J Nephrology Giuseppe Coppolino et al. discuss the important topic of acute kidney injury in patients undergoing cardiac surgery.


In this issue of NDT-E there will be a final opportunity for you to do the obesity survey in two parts; one testing your knowledge about this common feature of CKD and one practice pattern part. You will also be able to view a new video in which the new NDT councillor Dr Sever from Turkey presents himself. Finally, if you have questions or comments regarding nutrition in your renal patients do not hesitate to post them on the nutritional blog. Several interesting comments have already been posted and could be discussed.


Enjoy your NDT-E


Peter Stenvinkel, Editor-in-chief