Editorial Issue 242

Does frequent nocturnal hemodialysis promote a more rapid loss of residual kidney function?

In this issue of NDT-E you will find some interesting novel papers to read. In a narrative review that recently came on-line in Kidney International, Kenar Jhaveri et al. discuss glomerular diseases seen with cancer and chemotherapy. You will also find a systematic review and meta-analysis of the relation between body mass index and short-term donor outcome of laparoscopic donor nephrectomy that will be published in Kidney Int by Jeffrey A Lafranca et al. John Daugirdas et al. present the results of a clinical trial on the effect of frequent hemodialysis on residual kidney function performed by the FHN Trial Group. The results show that frequent nocturnal hemodialysis appears to promote a more rapid loss of residual kidney function, the mechanism of which remains to be determined. Yoshimi Takamiya et al. present an interesting paper published in Nephrol Dial Transpl showing that experimental diabetic nephropathy is accelerated in matrix metalloproteinase-2 knockout mice. I also think that you may find the NDT paper by Marian Goicoechea et al., which shows that the prevalence of acute tubulointerstitial nephritis has increased in recent years, especially in patients aged more than 65 years, interesting. The authors speculate that this could be due to an increase in drug-associated acute tubulointerstitial nephritis.



In this issue you will also find four CME lectures presented at the ERA-EDTA meeting in Paris May 2012. In the first lecture Dr. Christian Combe, Bordeaux, France will present a lecture entitled “WHAT IS EARLY START AND WHY IT SHOULD NOT BE SYSTEMATIC?” The 2nd lecture is entitled ”WHAT IS LATE START AND WHY IS IT HARMFUL?” and is presented by Dr. Charles Tomson, Bristol, UK. Dr. James Tattersal, Leeds, UK in his lecture ”WHEN TO START OF DIALYSIS: GUIDELINE AND REALITY” will show that eGFR is useless as a guide to initiating dialysis. The final CME lecture is presented by Dr. Ercan Ok, Izmir, Turkey and is entitled ”LONG DIALYSIS SESSIONS (DAILY, NOCTURNAL ETC)”


In this issue of NDT-E you will also find a web-link to the EuTRiPD (European Training and Research in Peritoneal Dialysis) consortium. The obesity survey is now closed. The results of the survey will be published in the NDT supplement on obesity later this spring. A new survey has been published: "Special issues in renal osteodystrophy, ROD" by Vincent Brandenburg and Thilo Krüger, please take few minutes to answer it! You will also be able to view a video in which the new NDT councillor Prof Foque presents himself and a video where Prof Suleymanlar invites to participate in the next ERA-EDTA Congress in Istanbul.


Enjoy your NDT-E!


Peter Stenvinkel, Editor-in-chief