Editorial issue 246

Mild hyponatremia is associated with an increased risk of death

In the 246th issue of NDT-E you will find several novel interesting papers to read. In a paper recently published in Kidney International, Dr Fabrice Gankam-Kengne et al. used data from the Dallas Heart Study and found that mild hyponatremia (serum sodium <135 mEq/l) is associated with an increased risk of death in an ambulatory setting. In another paper recently published in Kidney Int, Carole Oudot et al. show that dietary salt depletion has beneficial effects on renal and metabolic alterations associated with a high-fructose diet in rats. Several interesting papers were published in the April issue of Nephrol Dial Transpl. First, Chaim Charytan et al. published a RCT, which showed that Ferric carboxymaltose in doses of 200 mg for HD-CKD patients and up to 1000 mg in NDD-CKD patients were well-tolerated and displayed comparable efficacy to other IV iron formulations. In another NDT paper Kozo Tanno et al. showed data suggesting that single status is a significant predictor for all-cause mortality and CVD mortality and that divorced/widowed status is a significant predictor for CVD mortality in HD patients. Finally, Karlijn J. Van Stralen et al. have published a paper on the impact of graft loss among kidney diseases with a high risk of post-transplant recurrence in the paediatric population.

In this issue of NDT-E you will also find four CME lectures presented at the ERA-EDTA meeting in Paris May 2012. Dr Véronique Fremeaux-Bacchi, Paris, France presents an interesting lecture entitled “ATYPICAL HUS AND THE COMPLEMENT SYSTEM”. The 2nd lecture is entitled ”C3 GLOMERULONEPHRITIS AND CFHR5 NEPHROPATHY” and is presented by Dr Patrick Maxwell, London, UK. The 3rd lecture by Dr Jan T. Kielstein, Hanover, Germany will present information on ”EHEC: THE GERMAN 2011 EPIDEMIC”. The final CME lecture is presented by Dr Harry Van Goor, Groningen, Netherlands and is entitled ” THE BIOLOGY OF ADAMs IN RENAL DISEASES”.

In this issue of NDT-E you can also do the novel bone survey in two parts; one testing your knowledge about this adynamic bone disease and one practice pattern part. We also invite you to visit and comment the Nutrition Blog.

Enjoy your NDT-E

Peter Stenvinkel, Editor-in-chief