Editorial issue 256

In this 256th issue of NDT-Edu, let me highlight the experimental paper «amelioration of ischemic brain damage by peritoneal dialysis» by Maria del Carmen Godino et al. in the Journal of Clinical Investigation. These authors performed  middle cerebral artery ligation, thus causing stroke in rats. The group of rats treated with PD had a much better outcome . The authors ascribe the impressive improvement to the removal via PD of glutamate, a neurotransmitter. This ground-breaking work definitely opens new avenues! Secondly, I have selected the paper «Reduction and residual proteinuria are therapeutic targets in type 2 diabetes with overt nephropathy: a post hoc analysis (Orient – proteinuria)» published by E. Imai et al. in NDT. The paper illustrates the importance of optimal control of proteinuria in renal disease. In the third paper, published in Kidney International, SM Hagen et al. publish a systematic review of the influence of peritoneal dialysis catheter type on complication rate and catheter survival. In the fourth one, again in Kidney International, J. Titze et al. review the recent data on sodium storage in skin and elsewhere, in a paper called «Spooky sodium balance». Needless to say that the topic is important for any nephrologist.

And the last paper is a review by T. Speer et al. of the role of high-density lipoprotein in uraemic dyslipidaemia. Again very relevant for us as nephrologists.


As usual, you will also find 4 CME lectures from the 50th ERA-EDTA Congress of Istanbul (May 2013). The first one was presented by Prof. Carmine Zoccali (Reggio di Calabria, Italy),  entitled «How to assess lung congestion in dialysis patients: LUST: an ERA-EDTA supported study».

In the second one, Prof. Stefan Jacobson (Stockholm, Sweden) discusses whether hemodialysis 3 times per week is acceptable as a standard therapy.

A third presentation by Prof. Ercan Ok (Izmir, Turkey) discusses the impact of online hemodiafiltration on mortality and cardiovascular outcomes.

Finally, Prof. Antonio Santoro (Bologna, Italy) presents «The intradialytic biofeedback and the cardiovascular stability in hypotension-prone patients» 


Enjoy NDT-Edducational


Prof. Michel Jadoul

Editor-in-Chief NDT-Educational