Editorial issue 275

Nephrology is diverse! Look at the four selected papers for this NDT-E issue. In the first paper, C. Zoja et al (from Remuzzi’s group in  Bergamo, Italy) review in NDT the topic of "Progression of renal injury toward interstitial inflammation and glomerular sclerosis is dependent on abnormal protein filtration". Next T. Cornelis et al publish in NDT too "An international feasibility study of home haemodialysis in older patients". Then, A. Dahlmann A. et al publish in Kidney Int on "Magnetic resonance-determined sodium removal from tissue stores in hemodialysis patients". This paper extends to humans the groundbreaking experiments from the group of Titze (Erlangen, Germany) on sodium storage in skin! In the fourth paper, N. Paragas et al demonstrate in an experimental study in the JCI that α-Intercalated cells defend the urinary system from bacterial infection.
Overall, the 4 papers thus cover from clinical nephrology and CKD, to dialysis, various aspects of physiology (sodium, potassium, urinary tract infection) and kidney transplantation!

The 3 CME lectures deal with nutritional aspects, inflammation and cardiovascular risk. Pr Giovanni Gambaro (Rome, Italy) discusses "Is there a risk of cardiovascular  disease in renal stone formers?". Next  Pr Peter Stenvinkel (Stockholm, Sweden) reviews the field of "The inflamed uremic phenotype – a mediator of premature aging". Finally, Pr Gunnar H. Heine (Homburg, Germany) presents the topic of "Monocyte heterogeneity and CV risk in CKD".

Enjoy NDT-E!.

Prof. Michel Jadoul
Editor-in-Chief NDT-Educational