Editorial issue 281

Let  me start this editorial with an unusual feature. The first paper, among the 5 selected for this issue, is in fact the text of a conversation of the Journal of Clinical investigation (JCI) editors  with Professor  Peter Agre, awarded a few years ago the Chemistry Nobel  Prize for his seminal work on aquaporins, the ubiquitous water channels. The content of this interview may be of interest to young nephrologists, especially when Professor Agre describes how  his research interests developed over the years. In the second paper, also from the JCI, Y. Y. Cai Y et al report that "Altered trafficking and stability of polycystins underlie polycystic kidney disease". In the third paper, A. Sha A et al report in NDT on "Severe vascular calcification and tumoral calcinosis in a family with hyperphosphatemia: a fibroblast growth factor 23 mutation identified by exome sequencing". The last 2 papers are from the Cliniical Kidney Journal (CKJ). Barbour S et al report "The need for improved uptake of the KDIGO glomerulonephritis guidelines into clinical practice in Canada: a survey of nephrologists". Next A. Edwards-Richards A et al in publish on "Capillary rarefaction: an early marker of microvascular disease in young hemodialysis patients".


CME lectures  

The 4 lectures of this issue, presented at ERA-EDTA congress in Amsterdam,  all deal with some aspects  of intensified dialysis. Dr Muriel Grooteman (Amsterdam, The Netherlands) first discusses "How to achieve high volume hemodiafiltration".

Then Dr Sandip Mitra (Manchester, UK). reviews "Home haemodialysis – modalities and prescribing strategies". Next ,  the topic of Dr Brigit van Jaarsveld (Amsterdam, The Netherlands) is "Nocturnal in-center haemodialysis: practical issues and clinical results". Finally  Pr James Tattersall (Leeds, UK). discusses "Anticoagulation for intensified dialysis strategies".


Enjoy NDT-Edu!

Prof. Michel Jadoul
Editor-in-Chief NDT-Educational