Scientists Target Enzyme In Bid To Tackle Chronic Kidney Disease

New research which aims to tackle chronic kidney disease is underway at Nottingham Trent University. Scientists are investigating the enzyme Transglutaminase-2 (TG2) - known to be responsible for kidney scarring and failure - to see how it can be targeted and blocked before serious problems occur.

It is hoped that, for the first time, the project could lead to the development of new drugs capable of halting the progression of kidney disease - a gradual irreversible damage to kidney function, for which there is no cure. The work is being funded by national charity Kidney Research UK. 

The disease, which costs the NHS £3.66bn a year, is thought to be getting more common because of its links with Type 2 diabetes, the result of increasing problems of obesity and ageing societies.

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