Certain genetic variants may influence progression of kidney disease

A new study suggests that patients with focal segmental glomerulosclerosis - a type of kidney disease - may have a more advanced form of the condition at diagnosis if they possess certain genetic variants, with this association being strongest among African Americans.

The researchers, including Dr. Jeffery Kopp of the National Institutes of Health, publish their findings in the Journal of the American Society of Nephrology.

Focal segmental glomerulosclerosis (FSGS) is scarring in kidney tissue that affects more than 5,000 people in the US every year. Symptoms of the condition include foamy urine (caused by excess protein), weight gain, swelling (caused by excess body fluids) and poor appetite.

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