Unlocking the kidney riddle in newborns

Researchers are closer to understanding why babies born with smaller kidneys have a high risk of developing cardiovascular disease.

The findings, published in the journal, Circulation, could have important implications for affected children, who are more likely to develop chronic kidney disease and high blood pressure as adults.

Currently, renal disorders at birth affect about one in 500 babies. Many of these babies go on to lead healthy normal lives, however 20-40 per cent will develop chronic kidney disease and high blood pressure. Unfortunately, these conditions are the main cause of end-stage kidney disease and the need for dialysis in children. What is unknown is why, or which, child will be adversely affected.

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