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- NDT-Edu news
- April 2017
- March 2017
- February 2017
- October 2016
- September 2016
- March 2016
- September 2015
- February 2016
- Type 2 diabetes: blood pressure drugs may be harmful for some patients
- Sleep apnea linked with an increased risk of chronic kidney disease
- National underutilization of preemptive and early kidney transplants
- ERA-EDTA recommendation on the use of tolvaptan in polycystic kidney disease
- Researchers discover a genetic mutation that prevents diabetes complications
- The history of hemodialysis sheds light on the ethical use of limited medical resources
- Implantable artificial kidney based on microchips sees major progress
- January 2016
- July 2015
- May 2015
- June 2015
- April 2015
- March 2015
- February 2015
- January 2015
- Alternate drug therapy lowers antibodies in kidney patients - may decrease the likelihood of organ rejection
- Certain genetic variants may influence progression of kidney disease
- Finger prick testing in diabetes could be replaced by tattoo-like sensor
- Should a more frequent dialysis schedule be applied?
- Unlocking the kidney riddle in newborns
- High blood calcium linked with increased risk of premature death in dialysis patients
- November 2014
- October 2014
- Potential blood test for disorder that can accelerate organ failure in kidney transplant recipients
- Kidney disease patients' risk of developing heart failure predicted by blood tests
- New pathway identified that links the brain to high blood pressure
- Pre-eclampsia may be caused by the fetus, not the placenta, says Anaesthesia editorial
- Novel RNAi-based therapy for anemia stimulates liver to produce EPO
- Metabolic genetics research paves way to treating diabetes and obesity
- Binge drinking in young men linked with increased risk of hypertension
- Fewer women than men receive hemodialysis treatment
- September 2014
- Including accessory arteries in renal denervation found to be more successful
- Building replacement kidneys in the lab
- Hypertension may be initiated by an autoimmune response
- Diabetes gene discovered in mice and men
- Invasive kidney biopsy for lupus patients may be replaced by math model
- Plant-derived compound 'may effectively treat lupus with fewer side effects'
- Transplant recipients infected with BK virus at increased risk of rejection
- August 2014
- NDT study shows: Infant mortality rate for babies of on-dialysis mothers is high
- Reviews address challenges of interpreting troponin levels in patients with chronic kidney disease
- Atypical antipsychotic drug use increases risk for acute kidney injury
- Coronary calcium predicts heart disease risk in patients with chronic kidney disease
- June 2014
- Findings show benefit of changing measure of kidney disease progression
- In type 1 diabetes, improved glucose control slows progression to end-stage renal disease
- New technique uncovers the building blocks of kidney regeneration
- Link between reduced kidney function and higher risk of kidney and urothelial cancers
- April 2014
- March 2014
- Kidney failure: nanofiber mesh "a cheap, wearable alternative to dialysis"
- Common causes of kidney dysfunction after transplantation detected by simple urine test
- Children with glomerular kidney disease more likely to have hypertension as adults
- Kidney disease caused by diabetes may be prevented by autoimmune drug
- Children in the UK are eating too much salt, new study finds
- February 2014
- January 2014
- November 2013
- Chronic kidney disease may be caused by epigenetic changes
- Preventing damage to kidneys by blocking signal-transmitting cellular pores
- Use of calcium-channel blocker and antibiotic associated with small increased risk of kidney injury
- Kidney disease progression hastened in African-Americans by gene variant
- Kidney disease patients who consume more vegetable protein may live longer
- In new model, kidney repair may not require stem cells
- October 2013
- Validated novel risk score developed to predict new onset end-stage renal disease
- Biological link between diabetes and heart disease found
- Overweight and obese children face high risk of hypertension
- Young transplant patients 'at higher risk of kidney disease'
- Study finds vitamin D does not contribute to kidney stones
- Risk of future stroke increased by hypertension during pregnancy
- In mouse model of diabetic kidney disease, enzyme restores function
- Genes involved in kidney disease identified by
- July 2013
- Urine Test Predicts Transplanted Kidney Rejection
- Findings May Help Explain Why Blacks Are More Prone To Develop Kidney Failure Than Whites
- Increasing Rates Of Hypertension Among Children, Adolescents
- Medication-resistant hypertension present in most people with moderate kidney disease
- High Blood Pressure Reduced By Removing Nerves Connecting Kidney To The Brain
- June 2013
- January 2013
- New Target For Treating Prediabetes In Patients With Kidney Disease
- Searching For Genetic Clues To Insulin Production
- Cut Down On Alcohol For Healthy Weight
- Triple Mix Of Blood Pressure Drugs And Painkillers Linked To Kidney Problems
- Link Between High Salt Intake And Social Inequalities
- Discovery Could Lead To Dramatic Improvements For People Managing Diabetes
- Discovery Could Lead To Dramatic Improvements For People Managing Diabetes
- Should A Patient's Weight Affect Kidney Transplant Decisions?
- Patients With Both Atrial Fibrillation And Chronic Kidney Disease At Greater Risk For End-Stage Renal Disease
- During Pregnancy, Hypertension Increases Risk Of Future End-Stage Renal Disease
- February 2013
- Risk For Type 1 Diabetes May Be Increased By Low Vitamin D Levels
- Do Gender And Ethnicity Alter Childhood Risk For Metabolic Syndrome?
- Dialysis Patients May Be Protected From Sudden Cardiac Death By Fish Oil
- Hemodiafiltration Prolongs Dialysis Patients' Lives
- Pregnant Women With High Blood Pressure At Increased Risk For Later Heart Disease
- Intravenous Fluid Used To Increase Blood Volume In Critically Ill Patients Associated With Increased Risk Of Death, Kidney Injury
- Use Of Catheters In Dialysis Linked With High Risk Of Infections, Heart Problems, And Death
- March 2013
- Lung Ultrasound Detects Congestion In Dialysis Patients May Help Save Lives
- In Pediatric Kidney Transplant Recipients, Antibody Response Linked With Rejection
- More Paired Kidney Exchanges Could Dramatically Increase Number Of Transplants
- African Americans With Kidney Disease And Fluctuating Blood Pressure At Increased Risk Of Premature Death
- April 2013
- Lab-Grown Kidney Transplanted Into Rats Produces Urine
- Kidney Disease In Older Age Linked To Overweight Starting In Early Adulthood
- The Correct Diet Can Help Avoid Kidney Disease
- Methods To Repair Kidney Cells, Assess Kidney Function On The Horizon
- In Mild Kidney Disease, Dietary Restriction May Be The Best Way To Reduce Phosphate's Negative Effects On The Heart
- Combined Liver-Kidney Transplantation May Benefit Some Patients With Complicated Childhood Polycystic Kidney Disease
- Alternative Therapies May Help Lower Blood Pressure
- Hormone Dramatically Increases Insulin Production, Possible Diabetes Breakthrough
- May 2013
- January 2012
- February 2012
- March 2012
- April 2012
- May 2012
- Living Kidney Donors Benefit From New Imaging Protocols
- Guidelines For Management Of Lupus Nephritis Issued By The American College Of Rheumatology
- Predicting Risk Of Death In End-Stage Kidney Disease, New Equation More Accurate
- Renal Denervation Lowers Blood Pressure In Kidney Disease Patients
- For Chronic Kidney Disease Patients, One Type Of Open Heart Surgery Is Safer Than The Other
- Peritonitis May Be A Deadly Condition For Some Kidney Failure Patients
- June 2012
- July 2012
- August 2012
- September 2012
- October 2012
- Risk For Cardiovascular Disease, Kidney Disease And Diabetes May Be Increased By Low Birth Weight
- Kidney Failure And Heart Disease In Diabetic Patients May Be Affected By Race
- New Home Hemodialysis Systems Are Easier For Kidney Disease Patients To Use
- Survival Of Transplanted Kidneys May Be Affected By Single Gene Variant In Donors
- Why Antibiotics Prescribed For Chemotherapy Cause Kidney Failure
- New Home Hemodialysis Systems Are Easier For Kidney Disease Patients To Use
- New Target For Treating Diabetic Kidney Disease, The Leading Cause Of Kidney Failure
- November 2012
- Studies Investigate Aspects Of Nutrition And Blood Pressure Control In Chronic Kidney Disease Patients
- Studies Investigate The Potential Of Several Drugs For The Treatment Of Patients With Diabetes Or Kidney Disease
- Link Between Circulating Blood Factor And A Leading Cause Of Kidney Failure
- Transplant Recipients At Increased Risk When Low Levels Of Donor-Specific Antibodies Present
- Scientists Target Enzyme In Bid To Tackle Chronic Kidney Disease
- Association Between A Decrease In Kidney Function And Cognitive Functioning
- Nobel winner and organ transplant pioneer Joseph Murray dies at 93
- Predicting Risk Of Chronic Kidney Disease Requires More Work On Models
- December 2012
Preventing damage to kidneys by blocking signal-transmitting cellular pores
One of the most devastating side effects of diabetes is kidney failure, and one of the earliest signs of kidney damage is a disruption of the organ's filtering capacity. Diabetes patients who develop kidney failure must go on dialysis, seriously limiting their quality of life and placing them at significantly increased risk of death. The incidence of kidney disease is increasing with rising rates of obesity-associated type 2 diabetes, but very little progress has been made towards protecting the kidney's filter barrier during the past 50 years.
Now a group of Massachusetts General Hospital (MGH) investigators has identified a molecule that plays a key role in the breakdown of the kidney filter, presenting a potential therapeutic target for stopping the damage before it becomes irreversible. Their report will appear in the December issue of the Journal of Clinical Investigation and is receiving early online release.