European Training Centres


Erlangen Staff


Nuremberg Staff

Peer Reviewed Publications in International Journals (only English) 2002-2005

Publications list

2002

Delles C, Jacobi J, John S, Fleischmann I, Schmieder RE (2002) Effects of enalapril and eprosartan on the renal vascular nitric oxide system in human essential hypertension. Kidney Int, 61: 1462-1468.

Delles C, Jacobi J, Schlaich MP, John S, Schmieder RE (2002) Assessment of endothelial function of the renal vasculature in human subjects. Am J Hypertens, 15: 3-9.

Delles C, Schneider MP, John S, Gekle M, Schmieder RE (2002) Angiotensin converting enzyme inhibition and angiotensin II AT1-receptor blockade reduce the levels of asymmetrical N(G), N(G)-dimethylarginine in human essential hypertension. Am J Hypertens, 15: 590-593.

Delles C, Weidner S, Schobel HP, Rupprecht HD (2002) Renal-artery stenosis in a patient with Takayasu's arteritis. Nephrol Dial Transplant. 17: 1339-1341.

Delles C, Wittmann M, Renders L, Kunzendorf U, Bohner C, Wutke R, Lang W, Schott GE, Rupprecht HD (2002) Restoration of renal allograft function by endovascular stenting of an iliac artery dissection. Nephrol Dial Transplant, 17: 1116-1118.

Dötsch J, Schoof E, Schöcklmann HO, Brüne B, Knerr I, Repp R, Rascher W (2002) Nitric oxide increases adrenomedullin receptor function in rat mesangial cells. Kidney Int, 61: 1707-1713.

Eckardt, K.-U.*, R. Bittner, J.W. Dudenhausen, U. Frei. (2002) Post-partum “acute renal failure“. Nephrol Dial Transpl 17: 1703-1705.

Fleischmann EH, Kruppenbacher J, Bock HL, Weber M (2002) Active immunization against hepatitis A in dialysis patients. Nephrol Dial Transplant. 17: 1825-1828.

Fleischmann EH, Schlaich MP, Schmidt BM, Oehmer S, Schmieder RE (2002) Hypercholesterolaemia and treatment with statins do not alter L-arginine-induced changes of renal haemodynamics. Nephrol Dial Transplant, 17: 1758-1765.

Fleischmann EH, Schmieder RE (2002) Are all antihypertensive drug classes equal in reducing left ventricular hypertrophy? Curr Cardiol Rep 4: 474-478.

Garlichs CD, Geis T, Goppelt-Struebe M, Eskafi S, Schmidt A, Schulze-Koops H, Ludwig J, Daniel WG, Schmeisser A (2002) Induction of cyclooxygenase-2 and enhanced release of prostaglandin E(2) and I(2) in human endothelial cells by engagement of CD40. Atherosclerosis. 163:9-16.

Goppelt-Struebe M, Heusinger-Ribeiro J, Fischer B (2002) Dual role of cytochalasin D in the regulation of connective tissue growth factor. Ann N Y Acad Sci. 973: 57-59.

Gosse P, Dubourg O, Gueret P, De Simone G, Schmieder R , De Leeuw PW, Degaute JP, Garcia Puig J, Karpov Y, Magometschnigg D, Matos L, Amouyel P, Asmar R, Le Heuzey JY, Nieminen M, Dahlof B (2002) Efficacy of very low dose perindopril 2 mg/indapamide 0.625 mg combination on left ventricular hypertrophy in hypertensive patients: the P.I.C.X.E.L. study rationale and design. J Hum Hypertens, 16: 653-659.

Graf S, Schischma A, Eberhardt KE, Istel R, Stiasny B, Schulze BD (2002) Intracranial aneurysms and dolichocestasia in autosomal dominant polycystic kidney disease. Nephrol Dial Transplant, 17: 819-823.

Hahn A, Barth H, Kress M, Mertens PR, Goppelt-Struebe M (2002) Role of Rac and Cdc42 in lysophosphatidic acid-mediated cyclooxygenase-2 gene expression. 2001, Biochem J, 362: 33-40.

Hartner A, Cordasic N, Klanke B , Mueller U, Sterzel RB, Hilgers KF (2002) The alpha8 integrin chain affords mechanical stability to the glomerular capillary tuft in hypertensive glomerular disease. Am J Pathol, 160:861-867.

Hartner A, Dötsch J (2002) Lessons in congenital and acquired renal disease from alpha8 integrin mutant mice. Pediatr Nephrol, 17: 882-888.

Hartner A, Haas C, Amann K, Sterzel RB. (2002) Aspects of the renal phenotype of adult alpha8 integrin-deficient mice. Nephrol Dial Transplant.;17 Suppl 9: 71-72.

Hashemolhosseini S, Hadjihannas M, Haas C, Amann K, Wegener M (2002) Restricted expression of mGCMa in kidney ind thymus. Mech Dev, 118: 175-178.

Hilgers KF (2002) Monocytes/macrophages in hypertension. J Hypertens, 20: 593-596.

Hilgers KF, Mann JF (2002) ACE inhibitors versus AT1 receptor antagonists in patients with chronic renal disease. J Am Soc Nephrol, 13: 1100-1108.

Hilgers KF, Mann JF (2002) Renoprotection with antihypertensive agents. Lancet, 359: 1693.

Hilgers KF, Schmieder RE (2002) Association studies in cardiovascular medicine. J Hypertens, 20: 173-176.

Hilgers KF, Stumpf C (2002) Angiotensin II, the endothelium and superoxide anions. J Hypertens, 20: 1271-1273.

Heusser K, Schobel HP, Adamidis A, Fischer T, Frank H (2002) Cardiovascular effects of beta-blockers with and without intrinsic sympathomimetic activity. A comparison between celiprolol and metoprolol. Kidney Blood Press Res. 25: 34-41.

Hörstrup, J., M. Gehrmann, B. Schneider, A. Plöger, P. Froese, T. Schirop, D. Kampf, U. Frei. R. Neumann, K.-U. Eckardt.* (2002) Elevation of serum and urine levels of TIMP-1 and tenascin in patients with renal disease. Nephrol Dial Transpl 17:1005-1013.

Hugo C, Kang DH, Johnson RJ (2002) Sustained expression of Thrombospondin-1 is associated with glomerular and tubulointerstitial fibrosis in the remnant kidney model. Nephron, 90: 460–470.

Jacobi J, Schneider MP, John S, Schmieder RE (2002) Impact of NO-synthase inhibition on renal hemodynamics in normotensive and hypertensive subjects. J Hypertens, 20: 525-530.

John S, Schmieder RE (2002) Are COX-2 inhibitors a risk factor for cardiovascular disease? Dtsch Med Wochenschr, 127: 156-159.

Klingbeil AU, John S, Schneider MP, Jacobi J, Weidinger G, Schmieder RE (2002) AT1-receptor blockade improves augmentation index: a double-blind, randomized, controlled study. J Hypertens, 20: 2423-2428.

Kunzendorf U, Hohenstein B, Oberbarnscheid M, Muller E, Renders L, Schott GE, Offermann G (2002) Duration of donor brain death and its influence on kidney graft function. Am J Transplant, 2: 292-294.

Lambert EA, Thompson J, Schlaich M, Laude D, Elghozi JL, Esler MD, Lambert GW (2002) Sympathetic and cardiac baroreflex function in panic disorder. J Hypertens, 20: 2445-2451.

Linz P, Veelken R (2002) Serotonin 5-HT(3) receptors on mechanosensitive neurons with cardiac afferents. Am J Physiol Heart Circ Physiol, 282: H1828-1835.

Nagasawa Y, Matthiesen S, Onuchic LF, Hou X, Bergmann C, Esquivel E, Senderek J, Ren Z, Zeltner R, Furu L, Avner E, Moser M, Somlo S, Guay-Woodford L, Buttner R, Zerres K, Germino GG. (2002) Identification and characterization of Pkhd1, the mouse orthologue of the human ARPKD gene.J Am Soc Nephrol.;13:2246-58.

Neureiter D, Frank H, Kunzendorf U, Waldherr R, Amann K (2002) Dialysis-associated acquired cystic kidney disease imitating autosomal dominant polycystic kidney disease in a patient receiving long-term peritoneal dialysis. Nephrol Dial Transplant, 17: 500-503.

Onuchic LF, Furu L, Nagasawa Y, Hou X, Eggermann T, Ren Z, Bergmann C, Senderek J, Esquivel E, Zeltner R, Rudnik-Schoneborn S, Mrug M, Sweeney W, Avner ED, Zerres K, Guay-Woodford LM, Somlo S, Germino GG. (2002) PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin-transcription-factor domains and parallel beta-helix 1 repeats. Am J Hum Genet.;70:1305-17.

Oppert, M., A. Reinicke, C. Müller, D. Barckow, U. Frei, K.-U. Eckardt*. ( 2002) Elevations in procalcitonin but not C-reactive protein are associated with pneumonia after cardiopulmonary resuscitation. Resuscitation 53:167-170.

Rosenberger, C., S. Mandriota, J.S. Jürgensen, M.S. Wiesener*, J.H. Hörstrup, U. Frei, P.J. Ratcliffe, P.H. Maxwell, S. Bachmann, K.-U. Eckardt*. ( 2002) Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys. J Am Soc Nephrol 13:1721-1732.

Rost S, Daniel C, Schulze-Lohoff E, Bäumert J, Lambrecht G, Hugo C (2002) P2 receptor antagonist PPADS inhibits mesangial cell proliferation in experimental mesangial proliferative glomerulonephritis. Kidney Int, 62: 1659-1671.

Schlaich MP, Klingbeil A, Jacobi J, Delles C, Schneider MP, Schmidt B, Schmieder RE (2002) Altered aldosterone response to salt intake and angiotensin II infusion in young normotensive men with parental history of arterial hypertension. J Hypertens, 20: 117-124.

Schmieder RE, Delles C (2002) Microalbuminuria. Test for this risk factor! MMW Fortschr Med, 144: 47-48.

Schmieder RE, Schneider MP (2002) Left ventricular hypertrophy. Recent aspects of diagnosis and therapy. MMW Fortschr Med, 144: 45-46.

Schobel HP, Frank H, Naraghi R, Geiger H, Titz E, Heusser K (2002) Hypertension in patients with neurovascular compression is associated with increased central sympathetic outflow. J Am Soc Nephrol. 13: 35-41.

Schunkert H, Schmieder R (2002) Are the benefits of antihypertensive therapy only due to blood pressure reduction? J Hypertens, 20: 2095-2096.

Stiasny B, Ziebell D, Graf S, Hauser IA, Schulze BD (2002) Clinical aspects of renal transplantation in polycystic kidney disease. Clin Nephrol, 58: 16-24.

Titze J, Krause H, Hecht H, Dietsch P, Rittweger J, Lang R, Kirsch KA, Hilgers KF (2002) Reduced osmotically inactive Na storage capacity and hypertension in the Dahl model. Am J Physiol Renal Physiol, 283: F134-141.

Unsoeld H, Krautwald S, Voehringer D, Kunzendorf U, Pircher H (2002) Cutting edge: CCR7+ and CCR7- memory T cells do not differ in immediate effector cell function. J Immunol, 169: 638-641.

Veelken R, Schmieder RE (2002) Neutral endopeptidase inhibition: the potential of a new therapeutic approach in cardiovascular disease evolves. J Hypertens, 20: 599-603.

Weber G., J. Gross, A. Kromminga, H.H. Loew, K.-U. Eckardt*. Allergic skin and systemic reactions in a patient with pure red cell aplasia and anti-erythropoietin antibodies challenged with different epoetins. (2002) J Am Soc Nephrol 13: 2381-2383.

Wiesener MS*, JS Jürgensen, C Rosenberger, C.K.Scholze, JH Hörstrup, C Warnecke, S. Mandriota, U Frei, CW Pugh, PJ Ratcliffe, S Bachmann, PH Maxwell, KU Eckardt*. (2002) Widespread, hypoxia-inducible expression of HIF-2 a in distinct cell populations of different organs. FASEB J 17: 271-3.

Wiesener, M.S.*, M. Seyfarth, C. Warnecke*, J.S. Jürgensen, C. Rosenberger, N.V. Morgan, E.R. Maher, U. Frei, K.-U. Eckardt*. ( 2002) Paraneoplastic erythrocytosis due to an inactivating point mutation of the von Hippel-Lindau gene in a renal cell carcinoma. Blood, 99:3562-5.

Willam, C., N. Masson, Y.M. Tian, S.A. Mahmood, M.I. Wilson, R. Bicknell, K-U Eckardt*, P.H. Maxwell, P.J. Ratcliffe, C.W. Pugh. (2002) Peptide blockade of HIF a degradation modulates cellular metabolism and angiogenesis. P NATL ACAD SCI USA, 99: 10423-10428.

Zyka,M. N.F. daSilva, S.C. Clifford, M.R. Morris, M.S. Wiesener*, K.-U. Eckardt*, R.S. Houlston, F.M. Richards, F. Latif, E.R. Maher. (2002) Identification of cyclin D1 and other novel targets for the von Hippel- Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease. Cancer Res, 62:3803-3811.

* Member of the Department in Erlangen/Nuremberg since January 2004

2003

Amann K, Tyralla K, Gross ML, Schwarz U, Törnig J, Haas CS, Ritz E, Mall G (2003) Cardiomyocyte loss in experimental renal failure – prevention by ramipril. Kidney Int, 63: 1708-1713.

Amann K, Veelken R (2003) Mechanisms and consequences of sympathetic hyperactivity in renal disease. Clin Nephrol, 60: S81-92.

Amann K, Haas CS. (2003) Renal lesions of paraproteinemias and fibrillary glomerulopathies. Pathologe 24: 444-448.

Bieritz B, Spessotto P, Colombatti A, Jahn A, Pröls F, Hartner A (2003) Role of a 8 integrin in mesangial cell adhesion, migration and proliferation. Kidney Int, 64: 119-127 Blood 99:3562-3565.

Daniel C, Takabatake Y, Mizui M, Isaka Y, Kawashi H, Rupprecht H, Imai E, Hugo C (2003) Antisense Oligonucleotides against Thrombospondin-1 inhibit activation of TGF-ß in fibrotic renal disease in the rat in vivo. Am J Path, 163: 1185-1192.

Dayoub H, Achan V, Adimoolam S, Jacobi J, Stuehlinger MC, Wang BY, Tsao PS, Kimoto M, Vallance P, Patterson AJ, Cooke JP. (2003) Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence. Circulation. 16;108:3042-7.

Delles C, Klingbeil AU, Schneider MP, Handrock R, Weidinger G, Schmieder RE (2003) Direct comparison of the effects of valsartan and amlodipine on renal hemodynamics in human essential hypertension. Am J Hypertens, 6: 1030-1035.

Delles C, Schmidt BM, Muller HJ, Oehmer S, Klingbeil AU, Schmieder RE (2003) Functional relevance of aldosterone for the determination of left ventricular mass. Am J Cardiol, 91: 297-301.

Delles C, Schmieder RE (2003) Endothelial function of the human renal vasculature. Dtsch Med Wochenschr, 128: 92-96.

Delles C, Schneider MP, Oehmer S, Fleischmann EH, Schmieder RE (2003) L-arginine-induced vasodilation of the renal vasculature is not altered in hypertensive patients with type 2 diabetes. Diabetes Care, 26: 1836-1840.

Ditting T, Linz P, Hilgers KF, Jung O, Geiger H, Veelken R (2003) Putative role of epithelial sodium channels (ENaC)in the afferent limb of cardio renal reflexes in rats. Basic Res Cardiol, 98: 388-400.

Dimmler A, Haas CS, Cho S, Hattler M, Forster C, Peters H, Schocklmann HO, Amann K. (2003) Laser capture microdissection and real-time PCR for analysis of glomerular endothelin-1 gene expression in mesangiolysis of rat anti-Thy 1.1 and murine Habu Snake Venom glomerulonephritis. Diagn Mol Pathol.;12:108-17.

Eikelis N, Schlaich MP, Aggarwal A, Kaye DM, Esler MD (2003) Interactions between leptin and the human sympathetic nervous system. Hypertension, 41: 1072-1079.

Fleischmann EH, Friedrich A, Danzer E, Gallert K, Walter H, Schmieder RE (2003) Intensive training of patients with hypertension is effective in modifying lifestyle risk factors. J Hum Hypertens, 18: 127-131.

Frank H, Schobel HP, Vitkowsky J, Schmieder RE, Heusser K (2003) Effects of angiotensin II receptor antagonism on the renal hemodynamic response to cardiovascular stress. Kidney Int, 63: 617-623.

Frank H, Werner D, Lorusso V, Klinghammer L, Daniel WG, Kunzendorf U, Ludwig J (2003) Simultaneous hemodialysis during coronary angiography fails to prevent radiocontrast-induced nephropathy in chronic renal failure. Clin Nephrol, 60: 176-182.

Goppelt-Struebe M, Esslinger B, Kunzendorf U (2003) Failure of cyclosporine A to induce transforming growth factor beta (TGF- ß ) synthesis in activated peripheral blood lymphocytes. Clin Transplant, 17: 20-25.

Griethe, W., R. Schmitt, J.S. Jürgensen, S. Bachmann, K.-U. Eckardt*, R. Schindler (2003) Bone morphogenic protein – 4 expression in vascular lesions of calciphylaxis. J Nephrol, 16:728-32.

Haas CS, Amann K, Schittny J, Blaser B, Muller U, Hartner A (2003) Glomerular and renal vascular structural changes in alpha8 integrin-deficient mice. J Am Soc Nephrol, 14: 2288-2296.

Hartner A, Cordasic N, Goppelt-Strübe M, Veelken R, Hilgers KF (2003) Role of macula densa cyclooxygenase-2 in renovascular hypertension. Am J Physiol Renal Physiol , 284: F498-502.

Hartner A, Cordasic N, Klanke B, Veelken R, Hilgers KF (2003) Strain differences in the development of hypertension and glomerular lesions induced by deoxycorticosterone acetate salt in mice. Nephrol Dial Transplant, 18: 1999-2004.

Hartner A, Hilgers KF, Bitzer M, Veelken R, Schöcklmann HO (2003) Dynamic expression patterns of TGFß2 and TGFß receptors in experimental glomerulonephritis. J Mol Med, 81: 32-42.

Hausknecht B, Voelkl V, Riess R, Gauer S, Goppelt-Struebe M (2003) Expression of Cyclooxygenase-2 in biopsies obtained from transplanted kidneys undergoing rejection. Transplantation, 76: 109-114.

Heusser K, Vitkovsky J, Raasch W, Schmieder RE, Schobel HP (2003) Elevation of sympathetic activity by eprosartan in young male subjects. Am J Hypertens, 16: 658-664.

Heusser K, Vitkovsky J, Schmieder RE, Schobel HP (2003) AT1 antagonism by eprosartan lowers heart rate variability and baroreflex gain. Auton Neurosci, 107: 45-51.

Hugo C (2003) The thrombospondin1 - TGF-ß axis in fibrotic renal disease. 1: Nephrol Dial Transplant, 18: 1241-1245.

Iwanciw D, Rehm M, Porst M, Goppelt-Struebe M (2003) Induction of connective tissue growth factor (CTGF) by angiotensin II – integration of signaling pathways. Arterioscler Thromb Vasc Biol, 23: 1782-1787.

John S, Schmieder RE (2003) Potential mechanisms of impaired endothelial function in arterial hypertension and hypercholesterolemia. Curr Hypertens Rep, 5: 199-207.

Jürgensen, J.S., R. Kettritz, W. Schneider, H. Koop, T.S. Hildebrand, U. Frei, K.-U. Eckardt*
(2003) Catastrophic antiphospholipid syndrome masquerading as ischemic colitis. Rheumatology International 23:204-206.

Kanwar YS, Pan X, Lin S, Kumar A, Wada J, Haas CS, Liau G, Lomasney JW. (2003) Imprinted mesodermal specific transcript (MEST) and H19 genes in renal development and diabetes. Kidney Int. 63:1658-1670.

Klingbeil AU, John S, Schneider MP, Jacobi J, Handrock R, Schmieder RE (2003) Effect of AT1 receptor blockade on endothelial function in essential hypertension. Am J Hypertens, 16: 123-128.

Klingbeil AU, Schneider M, Martus P, Messerli FH, Schmieder RE (2003) A meta-analysis of the effects of treatment on left ventricular mass in essential hypertension. Am J Med, 115: 41-46.

Konner K, Nonnast-Daniel B, Ritz E (2003) The arteriovenous fistula. J Am Soc Nephrol, 14: 1669-1680.

Ott C, Iwanciw D, Graness A, Giehl K, Goppelt-Struebe M (2003) Modulation of the expression of connective tissue growth factor by alterations of the cytoskeleton. J Biol Chem, 278: 44305-44311.

Renders L, Haas CS, Liebelt J, Oberbarnscheidt M, Schoecklmann HO, Kunzendorf U (2003) Tacrolimus and cerivastatin pharmacokinetics and adverse effects after single and multiple dosing with cerivastatin in renal transplant recipients. Br J Clin Pharmacol, 56: 214-219.

Rosenberger, C., W. Griethe, G. Gruber, M. Wiesener*, U. Frei, S. Bachmann, Eckardt, K.-U.* (2003) Cellular responses to hypoxia after renal segmental infarction. Kidney International 64: 874-886.

Saam T, Ehmke H, Haas C , Ritz E, Amann K. (2003) Effect of endothelin blockade on early cardiovascular remodeling in the one-clip-two-kidney hypertension of the rat. Kidney Blood Press Res. 26: 325-332.

Schlaich MP, Esler MD (2003) Sympathetic nerve activity in essential hypertension. New pathophysiologic aspects. Dtsch Med Wochenschr, 128: 677-681.

Schlaich MP, Kaye DM, Lambert E, Sommerville M, Socratous F, Esler MD (2003) Relation between cardiac sympathetic activity and hypertensive left ventricular hypertrophy. Circulation, 108: 560-565.

Schmidt BM, Schmieder RE. (2003) Response. Hypertension. Dec 1.

Schmidt BM, Oehmer S, Delles C, Bratke R, Schneider MP, Klingbeil A, Fleischmann EH, Schmieder RE (2003) Rapid nongenomic effects of aldosterone on human forearm vasculature. Hypertension, 42: 156-160.

Schmidt BM, Schmieder RE (2003) Aldosterone-induced cardiac damage: focus on blood pressure independent effects. Am J Hypertens, 16: 80-86.

Schmidt BMW, Rastätter A, Oehmer S, Schwarz TK, Schneider MP, Delles C, Schmieder RE (2003) Rapid nongenomic aldosterone affects - A pathophysiological factor in primary hypertension? J Am Soc Nephrol, 14: 514A.

Schmieder RE, Handrock R, VALUE-Studienärzte (2003) Control of systolic blood pressure in the VALUE trial after 12 months. Dtsch Med Wochenschr, 128: 485-486.

Schneider MP, Klingbeil AU, Delles C, Schmidt BM, John S, Schmieder RE. ( 2003) Vitamin C augments the renal response to L-arginine in smokers. Nephrol Dial Transplant.;18:1512-7.

Schneider MP, Delles C, Fleischmann E, Schmidt BM, John S, Schmieder RE (2003) Effect of elevated triglyceride levels on endothelium-dependent vasodilation in patients with hypercholesterolemia. Am J Cardiol, 91: 482-484.

Schneider MP, Hilgers KF, Huang Y, Delles C, John S, Oehmer S, Schmieder RE (2003) The C242T p22phox polymorphism and endothelium-dependent vasodilation in subjects with hypercholesterolaemia. Clin Sci, 105: 97-103.

Schneider MP, John S, Delles C, Schmidt B, Schwarz T, Schmieder RE (2003) In vitro markers do not correlate with the intraarterial assessment of oxidative stress in subjects with essential hypertension. Dtsch Med Wochenschr, 128: P88.

Schneider MP, Klingbeil AU, Delles C, Schmidt BM, John S, Schmieder RE (2003) Vitamin C augments the renal response to L-arginine in smokers. Nephrol Dial Transplant, 18: 1512-1517.

Titze J, Schneider M, Krause H, Jacobi J, Stolte M, Linke RP, Rupprecht HD. (2003) Diarrhea, nephrotic syndrome and hidradenitis suppurativa: an unusual case. Nephrol Dial Transplant. 18: 192-194.

Titze J, Lang R, Ilies C, Schwind KH, Kirsch KA, Dietsch P, Luft FC, Hilgers KF (2003) Osmotically inactive skin Na+ storage in rats. Am J Physiol Renal Physiol, 285: F1108-1117.

Veelken R, Stetter A, Dickel T, Hilgers KF (2003) Bimodality of cardiac vagal afferent C-fibres in the rat. Pflugers Arch, 446: 516-522.

Warnecke C*. , W. Griethe, A. Weidemann*, J.S. Jürgensen, C. Willam, S. Bachmann, Y. Ivaschenko, I. Wagner, U. Frei, M. Wiesener, K.-U. Eckardt*. (2003) activation of the hypoxia-inducible factor pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors. FASEB J 17 : 1186-1188 .

Wiese P, Blume J, Müller HJ, Renner H, Nonnast-Daniel B (2003) Clinical and Doppler ultrasonography data of a polyurethane vascular access graft for haemodialysis: a prospective study. Nephrol Dial Transplant, 18: 1397-1400

Zidek W, Dusing R, Haller H, Middeke M, Paul M, Schmieder R, Schrader J; German Society of Hypertension (2003) New recommendations of the German Hypertension League for the drug treatment of hypertension. Dtsch Med Wochenschr, 128: 2468-2469.

* Member of the Department in Erlangen/Nuremberg since January 2004

2004


Buzello M, Haas CS, Hauptmann F, Gross ML, Faulhaber J, Schultze-Mosgau S, Ehmke H, Ritz E, Amann K. No aggravation of renal injury in apolipoprotein E knockout mice (ApoE(-/-)) after subtotal nephrectomy. Nephrol Dial Transplant. 2004;19:566-73.
Cicha I, Garlichs CD, Daniel WG, Goppelt-Struebe M. Activated human platelets release connective tissue growth factor. Thromb Haemost. 2004;91:755-60.
Cicha I, Schneiderhan-Marra N, Yilmaz A, Garlichs CD, Goppelt-Struebe M. Monitoring the cellular effects of HMG-CoA reductase inhibitors in vitro and ex vivo. Arterioscler Thromb Vasc Biol. 2004;24:2046-50.
Daniel C, Pippin J, Shankland SJ, Hugo C. The rapamycin derivative RAD inhibits mesangial cell migration through the CDK-inhibitor p27KIP1. Lab Invest. 2004;84:588-96.
Daniel C, Wiede J, Krutzsch HC, Ribeiro SM, Roberts DD, Murphy-Ullrich JE, Hugo C. Thrombospondin-1 is a major activator of TGF-beta in fibrotic renal disease in the rat in vivo. Kidney Int. 2004;65:459-68.
Deinzer A, Hegemann T, Veelken R, Schmieder RE. [A model project on shared decision-making in the treatment of arterial hypertension] MMW Fortschr Med. 2004;146:48-50.
Delles C, Klingbeil AU, Schneider MP, Handrock R, Schaufele T, Schmieder RE. The role of nitric oxide in the regulation of glomerular haemodynamics in humans. Nephrol Dial Transplant. 2004;19:1392-7.
Delles C, Michelson G, Harazny J, Oehmer S, Hilgers KF, Schmieder RE. Impaired endothelial function of the retinal vasculature in hypertensive patients. Stroke. 2004 Jun;35(6):1289-93.
Delles C, Schluter C, Wittmann M, Renders L, Riess R, Rosch W, Schott GE, Rupprecht HD, Kunzendorf U. "Very delayed" graft function in a patient after living related kidney transplantation: a case report. Transplant Proc. 2004;36:1377-9.
Delles C, Schmieder RE. Renal endothelial effects of antihypertensive therapy. Curr Opin Nephrol Hypertens. 2004;13:489-93.
Delles C, Schneider MP, Oehmer S, Fleischmann I, Fleischmann EF, Schmieder RE. Increased response of renal perfusion to the antioxidant vitamin C in type 2 diabetes. Nephrol Dial Transplant. 2004;19:2513-8.
Ditting T, Hilgers KF, Scrogin KE, Stetter A, Linz P, Veelken R. Mechanosensitive cardiac C-fiber response to changes in left ventricular filling, coronary perfusion pressure, hemorrhage and volume expansion in rats. Am J Physiol Heart Circ Physiol. 2004 Oct 7; E-pub.
Ebbesen P, Eckardt KU, Ciampor F, Pettersen EO. Linking measured intercellular oxygen concentration to human cell functions. Acta Oncol. 2004;43:598-600.
Eikelis N, Lambert G, Wiesner G, Kaye D, Schlaich M, Morris M, Hastings J, Socratous F, Esler M. Extra-adipocyte leptin release in human obesity and its relation to sympathoadrenal function. Am J Physiol Endocrinol Metab. 2004;286:E744-52.
Eknoyan G, Lameire N, Barsoum R, Eckardt KU, Levin A, Levin N, Locatelli F, MacLeod A, Vanholder R, Walker R, Wang H. The burden of kidney disease: improving global outcomes. Kidney Int. 2004;66:1310-4.
Fenner M, Frankenberger R, Pressmar K, John S, Neukam FW, Nkenke E. Life-threatening thrombotic thrombocytopenic purpura associated with dental foci. J Clin Periodontol 2004;31:1019-1023
Fleischmann EH, Friedrich A, Danzer E, Gallert K, Walter H, Schmieder RE. Intensive training of patients with hypertension is effective in modifying lifestyle risk factors. J Hum Hypertens. 2004;18:127-31.
Fleischmann EH, John S, Delles C, Schneider MP, Schmidt BM, Schmieder RE. The effect of statins on angiotensin II-induced hemodynamic changes in young, mildly hypercholesterolemic men. Am J Hypertens. 2004;17:1120-6.
Frank H, Heusser K, Hoffken B, Huber P, Schmieder RE, Schobel HP. Effect of erythropoietin on cardiovascular prognosis parameters in hemodialysis patients. Kidney Int. 2004;66:832-40.
Gosse P, de Simone G, Dubourg O, Gueret P, Schmieder R. Serial echocardiographic assessment of left ventricular mass: how blinded should readers be? J Hypertens. 2004;22:1813-8.
Hartner A, Eifert T, Haas CS, Tuysuz C, Hilgers KF, Reinhardt DP, Amann K. Characterization of the renal phenotype in a mouse model of Marfan syndrome. Virchows Arch. 2004;445:382-8.
Heusinger-Ribeiro J, Fischer B, Goppelt-Struebe M. Differential effects of simvastatin on mesangial cells. Kidney Int. 2004;66:187-95.
Hilgers KF, Dotsch J, Rascher W, Mann JF. Treatment strategies in patients with chronic renal disease: ACE inhibitors, angiotensin receptor antagonists, or both? Pediatr Nephrol. 2004;19:956-61.
Hilgers KF, Veelken R. Type 2 Diabetic Nephropathy: Never too Early to Treat? J Am Soc Nephrol. 2005 Feb 9; Epub
Hochegger K, Knight S, Hugo C, Mayer G, Lawler J, Mayadas TN, Rosenkranz AR. Role of thrombospondin-1 in the autologous phase of an accelerated model of anti-glomerular basement membrane glomerulonephritis. Nephron Exp Nephrol. 2004;96:e31-8.
Hohenstein B, Daniel C, Wagner A, Stasch JP, Hugo C. Stimulation of Soluble Guanylyl Cyclase (sGC) Inhibits Mesangial Cell Proliferation and Matrix Accumulation in Experimental Glomerulonephritis. Am J Physiol Renal Physiol. 2004; Epub
Jacobi J, Tam BY, Sundram U, von Degenfeld G, Blau HM, Kuo CJ, Cooke JP. Discordant effects of a soluble VEGF receptor on wound healing and angiogenesis. Gene Ther. 2004;11:302-309
Jacobi J, Tam BYY, Wu G, Hoffman J, Cooke JP, Kuo CJ. Adenoviral gene transfer with soluble vascular endothelial growth factor receptors impairs angiogenesis and perfusion in a murine model of hindlimb ischemia. Circulation 2004;110: 2424-2429
Jurgensen JS, Rosenberger C, Wiesener MS, Warnecke C, Horstrup JH, Grafe M, Philipp S, Griethe W, Maxwell PH, Frei U, Bachmann S, Willenbrock R, Eckardt KU. Persistent induction of HIF-1alpha and -2alpha in cardiomyocytes and stromal cells of ischemic myocardium. FASEB J. 2004;18:1415-7.
Kostis JB, Packer M, Black HR, Schmieder R, Henry D, Levy E. Omapatrilat and enalapril in patients with hypertension: the Omapatrilat Cardiovascular Treatment vs. Enalapril (OCTAVE) trial. Am J Hypertens. 2004;17:103-11.
Kuhlmann A, Haas CS, Gross ML, Reulbach U, Holzinger M, Schwarz U, Ritz E, Amann K. 1,25-Dihydroxyvitamin D3 decreases podocyte loss and podocyte hypertrophy in the subtotally nephrectomized rat. Am J Physiol Renal Physiol. 2004;286:F526-33.
Lambert EA, Schlaich MP. Reduced sympathoneural responses to the cold pressor test in individuals with essential hypertension and in those genetically predisposed to hypertension. No support for the "pressor reactor" hypothesis of hypertension development. Am J Hypertens. 2004;17:863-8.
Locatelli F, Aljama P, Barany P, Canaud B, Carrera F, Eckardt KU, Macdougall IC, Macleod A, Horl WH, Wiecek A, Cameron S. Erythropoiesis-stimulating agents and antibody-mediated pure red-cell aplasia: here are we now and where do we go from here? Nephrol Dial Transplant. 2004;19:288-93.
Locatelli F, Aljama P, Barany P, Canaud B, Carrera F, Eckardt KU, Horl WH, Macdougal IC, Macleod A, Wiecek A, Cameron S; European Best Practice Guidelines Working Group. Revised European best practice guidelines for the management of anaemia in patients with chronic renal failure. Nephrol Dial Transplant. 2004;19 Suppl 2:ii1-47.
Melk A, Schmidt BM, Takeuchi O, Sawitzki B, Rayner DC, Halloran PF. Expression of p16INK4a and other cell cycle regulator and senescence associated genes in aging human kidney. Kidney Int. 2004;65:510-20.
Muehlich S, Schneider N, Hinkmann F, Garlichs CD, Goppelt-Struebe M. Induction of connective tissue growth factor (CTGF) in human endothelial cells by lysophosphatidic acid, sphingosine-1-phosphate, and platelets. Atherosclerosis. 2004;175:261-8.
Oppert M, Jorres A, Barckow D, Eckardt KU, Frei U, Kaisers U. Inhaled nitric oxide for ARDS due to sickle cell disease. Swiss Med Wkly. 2004;134:165-7.
Pinkau T, Hilgers KF , Veelken R, Mann JF. How does minor renal dysfunction influence cardiovascular risk and the management of cardiovascular disease? J Am Soc Nephrol. 2004;15:517-23.
Pinkau T, Hilgers KF, Veelken R, Mann JFE. How does minor renal dysfunction influence cardiovascular risk and the management of cardiovascular disease? J Am Soc Nephrol . 2004, 15:517-523.
Rossert J, Casadevall N, Eckardt KU. Anti-erythropoietin antibodies and pure red cell aplasia. J Am Soc Nephrol. 2004;15:398-406.
Schlaich MP, Ahlers BA, Parnell MM, Kaye DM. beta-Adrenoceptor-mediated, nitric-oxide-dependent vasodilatation is abnormal in early hypertension: restoration by L-arginine. J Hypertens. 2004;22:1917-25.
Schlaich MP, Esler MD. Response: Neural Sympathetic Activity in Essential Hypertension. Hypertension. 2004 Jun 7; Epub.
Schlaich MP, Lambert E, Kaye DM, Krozowski Z, Campbell DJ, Lambert G, Hastings J, Aggarwal A, Esler MD. Sympathetic augmentation in hypertension: role of nerve firing, norepinephrine reuptake, and Angiotensin neuromodulation. Hypertension. 2004;43:169-75.
Schlaich MP, Parnell MM, Ahlers BA, Finch S, Marshall T, Zhang WZ, Kaye DM. Impaired L-arginine transport and endothelial function in hypertensive and genetically predisposed normotensive subjects. Circulation. 2004;110:3680-6.
Schmidt BM, Schmieder RE. Response: Rapid Nongenomic Effects of Aldosterone on Human Forearm Vasculature. Hypertension 2004;
Schmieder RE, R. Veelken. Fallstricke in der Therapie der arteriellen Hypertonie. Herzmedizin 2004;21:24-26
Schmieder RE. Telmisartan/hydrochlorothiazide combination therapy in the treatment of essential hypertension. Expert Opin Pharmacother. 2004;5:2303-10.
Schneider MP, Klingbeil AU, Delles C, Ludwig M, Kolloch RE, Krekler M, Stumpe KO, Schmieder RE. Effect of irbesartan versus atenolol on left ventricular mass and voltage: results of the CardioVascular Irbesartan Project. Hypertension. 2004;44:61-6.
Schneider MP, Schmieder RE. Response. Expert Opin Pharmacother 2004.
Schulze BD. [Urine diagnosis and leukocyturia] MMW Fortschr Med. 2004 21;146:39-41.
Titze J , Rittweger J, Dietsch P, Krause H, Schwind KH, Engelke K, Lang R, Kirsch KA, Luft FC, Hilgers KF. Hypertension, sodium retention, calcium excretion and osteopenia in Dahl rats. J Hypertens. 2004;22:803-10.
Titze J, Shakibaei M, Schafflhuber M, Schulze-Tanzil G, Porst M, Schwind KH, Dietsch P, Hilgers KF. Glycosaminoglycan polymerization may enable osmotically inactive Na+ storage in the skin. Am J Physiol Heart Circ Physiol. 2004;287:H203-8.
Veelken R, Hilgers KF, Porst M, Krause H, Hartner A, Schmieder RE. Effects of Sympathetic Nerves and Angiotensin II on Renal Sodium and Water Handling in Rats with Common Bile Duct Ligature. Am J Physiol Renal Physiol. 2005 Feb 8; Epub
Verhelst D, Rossert J, Casadevall N, Kruger A, Eckardt KU, Macdougall IC. Treatment of erythropoietin-induced pure red cell aplasia: a retrospective study. Lancet. 2004;363:1768-71.
Warnecke C, Zaborowska Z, Kurreck J, Erdmann VA, Frei U, Wiesener M , Eckardt KU. Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells. FASEB J. 2004;18:1462-4.
Wellmann S, Guschmann M, Griethe W, Eckert C, von Stackelberg A, Lottaz C, Moderegger E, Einsiedel HG, Eckardt KU, Henze G, Seeger K. Activation of the HIF pathway in childhood ALL, prognostic implications of VEGF. Leukemia. 2004;18:926-33.
Werner D, Michalk F, Harazny J, Hugo C, Daniel WG, Michelson G. Accelerated reperfusion of poorly perfused retinal areas in central retinal artery occlusion and branch retinal artery occlusion after a short treatment with enhanced external counterpulsation. Retina. 2004;24:541-7.
Wiese P, Nonnast-Daniel B. Colour Doppler ultrasound in dialysis access. Nephrol Dial Transplant. 2004;19:1956-63.

Books
R. Lang. Dezentrale Personalwirtschaft im Großkrankenhaus. In: Beiträge zum Organisationsmanagement im Krankenhaus. Hrsg.: A. Putzhammer, U.M. Feser, G. Hajak. Shaker Verlag, Aachen 2004.
K.U. Klingbeil, R.E. Schmieder Compliance der großen Gefäße. In: Arterielle Hypertonie. Hrsg.: Kolloch R, Rosenthal J, Springer Verlag, 2004
M.P. Schneider, R.E. Schmieder. Die Regression der linksventrikulären Hypertrophie. Hrsg.: Kolloch R, Rosenthal J, Springer Verlag, 2004.

2005

Boven K, Knight J, Bader F, Rossert J, Eckardt KU, Casadevall N Epoetin-associated pure red cell aplasia in patients with chronic kidney disease: solving the mystery. Nephrol Dial Transplant. 2005;20 Suppl 3: iii33-iii40

Casadevall N, Eckardt KU, Rossert J Epoetin-induced autoimmune pure red cell aplasia. J Am Soc Nephrol. 2005;16 Suppl 1: S67-9

Cicha I, Yilmaz A, Klein M, Raithel D, Brigstock DR, Daniel WG, Goppelt-Struebe M, Garlichs CD Connective Tissue Growth Factor Is Overexpressed in Complicated Atherosclerotic Plaques and Induces Mononuclear Cell Chemotaxis In Vitro. Arterioscler Thromb Vasc Biol. 2005

Ditting T, Hilgers KF, Scrogin KE, Stetter A, Linz P, Veelken R Mechanosensitive cardiac C-fiber response to changes in left ventricular filling, coronary perfusion pressure, hemorrhage, and volume expansion in rats. Am J Physiol Heart Circ Physiol. 2005;288: H541-52

Dominiczak AF, Graham D, McBride MW, Brain NJ, Lee WK, Charchar FJ, Tomaszewski M, Delles C, Hamilton CA Corcoran Lecture. Cardiovascular genomics and oxidative stress. Hypertension. 2005;45: 636-42

Eckardt KU Managing a fateful alliance: anaemia and cardiovascular outcomes. Nephrol Dial Transplant. 2005;20 Suppl 6: vi16-vi20

Fellstrom B, Zannad F, Schmieder R, Holdaas H, Jardine A, Rose H, Wilpshaar W, The Aurora Study Group OB Effect of rosuvastatin on outcomes in chronic haemodialysis patients - design and rationale of the AURORA study. Curr Control Trials Cardiovasc Med. 2005;6: 9

Gradman AH, Schmieder RE, Lins RL, Nussberger J, Chiang Y, Bedigian MP Aliskiren, a novel orally effective renin inhibitor, provides dose-dependent antihypertensive efficacy and placebo-like tolerability in hypertensive patients. Circulation. 2005;111: 1012-8

Graness A, Giehl K, Goppelt-Struebe M Differential involvement of the integrin-linked kinase (ILK) in RhoA-dependent rearrangement of F-actin fibers and induction of connective tissue growth factor (CTGF). Cell Signal. 2005 [Epub ahead of print]

Hartner A, Veelken R, Wittmann M, Cordasic N, Hilgers KF Effects of diabetes and hypertension on macrophage infiltration and matrix expansion in the rat kidney. BMC Nephrol. 2005;6: 6

Hilgers KF, Veelken R Type 2 Diabetic Nephropathy: Never too Early to Treat? J Am Soc Nephrol. 2005;16: 574-5

Hohenstein B, Daniel C, Wagner A, Stasch JP, Hugo C Stimulation of soluble guanylyl cyclase inhibits mesangial cell proliferation and matrix accumulation in experimental glomerulonephritis. Am J Physiol Renal Physiol. 2005;288: F685-93

Hohenstein B, Kasperek L, Kobelt DJ, Daniel C, Gambaryan S, Renné T, Walter U, Amann KU, Hugo CP Vasodilator-Stimulated Phosphoprotein-Deficient Mice Demonstrate Increased Platelet Activation but Improved Renal Endothelial Preservation and Regeneration in Passive Nephrotoxic Nephritis. J Am Soc Nephrol. 2005;16:986-96.

Hutchison AJ, Maes B, Vanwalleghem J, Asmus G, Mohamed E, Schmieder R, Backs W, Jamar R, Vosskuhler A Efficacy, Tolerability, and Safety of Lanthanum Carbonate in Hyperphosphatemia: A 6-Month, Randomized, Comparative Trial versus Calcium Carbonate. Nephron Clin Pract. 2005;100: c8-c19

Jacobi J, Sydow K, von Degenfeld G, Zhang Y, Dayoub H, Wang B, Patterson AJ, Kimoto M, Blau HM, Cooke JP verexpression of dimethylarginine dimethylaminohydrolase reduces tissue asymmetric dimethylarginine levels and enhances angiogenesis. Circulation. 2005;111: 1431-8

John S, Schneider MP, Delles C, Jacobi J, Schmieder RE Lipid-independent effects of statins on endothelial function and bioavailability of nitric oxide in hypercholesterolemic patients. Am Heart J. 2005;149: 473

Lameire N, Eknoyan G, Barsoum R, Eckardt KU, Levin A, Levin N, Locatelli F, Macleod A, Vanholder R, Walker R, Wang H A new initiative in nephrology: kidney disease: improving global outcomes. Contrib Nephrol. 2005;149: 90-9

Levey AS, Eckardt KU, Tsukamoto Y, Levin A, Coresh J, Rossert J, Zeeuw D, Hostetter TH, Lameire N, Eknoyan G Definition and classification of chronic kidney disease: A position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int. 2005;67: 2089-100

Mark R. Morris 1,2, Dean Gentle 1,2, Mahera Abdulrahman 2, Esther N. Maina 2, Kunal Gupta 2, Rosamonde E. Banks 3, Michael S. Wiesener 4, Takeshi Kishida 5, Masahiro Yao 5, Bin Teh 6, Farida Latif 1,2 and Eamonn R. Maher 1,2 Tumor Suppressor Activity and Epigenetic Inactivation of Hepatocyte Growth Factor Activator Inhibitor Type 2/SPINT2 in Papillary and Clear Cell Renal Cell Carcinoma. C ancer Research 2005;65:4598-4606.

Melk A, Schmidt BM, Vongwiwatana A, Rayner DC, Halloran PF Increased Expression of Senescence-Associated Cell Cycle Inhibitor p16 in Deteriorating Renal Transplants and Diseased Native Kidney. Am J Transplant. 2005;5: 1375-82

Morris MR, Gentle D, Abdulrahman M, Maina EN, Gupta K, Banks RE, Wiesener MS, Kishida T, Yao M, Teh B, Latif F, Maher ER Tumor suppressor activity and epigenetic inactivation of hepatocyte growth factor activator inhibitor type 2/SPINT2 in papillary and clear cell renal cell carcinoma. Cancer Res. 2005;65: 4598-606

Riegel W, Hahn K, Kreutz R, Weber M, Zidek W, Schmieder R [Multi-centre enquiry into the influence of the referral of patients with progressive kidney disease to nephrologists.] Dtsch Med Wochenschr. 2005;130: 792-6

Rosenberger C, Heyman SN, Rosen S, Shina A, Goldfarb M, Griethe W, Frei U, Reinke P, Bachmann S, Eckardt KU Up-regulation of HIF in experimental acute renal failure: evidence for a protective transcriptional response to hypoxia. Kidney Int. 2005;67: 531-42

Rossert J, Eckardt KU Erythropoietin receptors: their role beyond erythropoiesis. Nephrol Dial Transplant. 2005 ;20:1025-8.

Schlaich MP, Kaye DM, Lambert E, Hastings J, Campbell DJ, Lambert G, Esler MD Angiotensin II and norepinephrine release: interaction and effects on the heart. J Hypertens. 2005;23: 1077-82

Schmieder RE [In Process Citation] MMW Fortschr Med. 2005;147: 10

Schmieder RE In Process Citation Krankenpfl J. 2005;43: 63

Schmieder RE Mechanisms for the Clinical Benefits of Angiotensin II Receptor Blockers. Am J Hypertens. 2005;18: 720-30

Schmieder RE Optimizing therapeutic strategies to achieve renal and cardiovascular risk reduction in diabetic patients with angiotensin receptor blockers. J Hypertens. 2005;23: 905-11

Schneider MP, Delles C, Schmidt BM, Oehmer S, Schwarz TK , Schmieder RE, John S Superoxide scavenging effects of N-acetylcysteine and vitamin C in subjects with essential hypertension. Am J Hypertens. 2005;18: 1111-7

Stumpf C, John S , Jukic J, Yilmaz A, Raaz D, Schmieder RE , Daniel WG, Garlichs CD Enhanced levels of platelet P-selectin and circulating cytokines in young patients with mild arterial hypertension. J Hypertens. 2005;23: 995-1000

Tauer A, Bender TO, Fleischmann EH, Niwa T, Jörres A, Pischetsrieder M Fate of the glucose degradation products 3-deoxyglucosone and glyoxal during peritoneal dialysis. Mol Nutr Food Res. 2005;49: 710-5.

Titze J, Bauer K, Schafflhuber M, Dietsch P, Lang R, Schwind KH, Luft FC, Eckardt KU, Hilgers KF Internal Sodium Balance in Desoxycorticosterone Acetate-Salt Rats: A Body Composition Study. Am J Physiol Renal Physiol. 2005 [Epub ahead of print]

Veelken R, Hilgers KF, Porst M , Krause H, Hartner A, Schmieder RE Effects of Sympathetic Nerves and Angiotensin II on Renal Sodium and Water Handling in Rats with Common Bile Duct Ligature. Am J Physiol Renal Physiol. 2005 ;288:F1267-75

Vincenti F, Tuncer M, Castagneto M, Klinger M, Friman S, Scheuermann EH, Wiecek A, Russ GR, Martinek A, Nonnast-Daniel B Prospective, multicenter, randomized trial to compare incidence of new-onset diabetes mellitus and glucose metabolism in patients receiving cyclosporine microemulsion versus tacrolimus after de novo kidney transplantation. Transplant Proc. 2005;37: 1001-4

Voegeli TA, Kurtz A, Grimm MO, Effert P, Eckardt KU Anemia under androgen deprivation: influence of flutamide, cyproteroneacetate and orchiectomy on the erythropoietin system. Horm Metab Res. 2005;37: 89-93

Walter H, Lübben G Potential role of oral thiazolidinedione therapy in preserving beta-cell function in type 2 diabetes mellitus. Drugs. 2005;65: 1-13

Warnecke C, Mugrauer P, Suerder D, Erdmann J, Schubert C, Regitz-Zagrosek V The intronic angiotensin II type 2 receptor gene polymorphism 1675 G/A modulates receptor protein expression but not mRNA splicing. Am J Physiol Regul Integr Comp Physiol. 2005 [Epub ahead of print]

European Fellows programme

Specify if the Unit accepts fellows from European countries for:
Short (1-2 month) well focused training programs either clinically or laboratory oriented: No.
Long (at least 1 year) research fellowships: Yes.
Specify corresponding availability of grants: No
Specify if the Unit may provide help for accommodation: Yes.

Prerequisites for Fellowship

Language: English or German

Work/Research experience: not essential, but desirable

Other prerequisites: On particular for clinical fellowships basic training on internal medicine is advantageous.

HEAD OF THE DEPARTMENT	Prof Dr K.-U. Eckardt
CONSULTANTS	Dr E. Fleischmann, Prof Dr K. Hilgers, PD Dr C. Hugo, PD Dr S. John, Dr R. Lang, Dr M. Leidig, Dr I. Mayer-Kadner, PD Dr B. Nonnast-Daniel, Prof Dr R. Schmieder, Prof Dr B. Schulze, Prof Dr R. Veelken, PD Dr H. Walter.
LABORATORY STAFF	Prof Dr M. Goppelt-Strübe, Dr A. Budde, Dr N. Cordasic, Dr C. Daniel, Dr A. Graness, Dr J. Heusinger-Ribeiro, Prof Dr K. Hilgers, Dr J. Jacobi, Dr B. Klanke, Dr P. Linz, Dr M. Porst, Dr A. Wagner, Dr C. Warnecke, Dr A. Weidemann

CONTACT INFORMATION
E-MAIL	med4@rzmail.uni-erlangen.de
PHONE:	+49-9131-8539002
FAX:	+49-9131-8539209
FULL POSTAL ADDRESS	Medizinische Klinik IV, Krankenhausstraße 12, 91054 Erlangen, Germany 4. Medizinische Klinik, Breslauer Straße 201, 91074 Nuremberg, Germany
WEBSITE OF THE UNIT	http://www.med4.med.uni-erlangen.de

CLINICAL FACILITIES
NEPHROLOGY BEDS N°	26 (Erlangen) and 124 (Nuremberg)
HEMODIALYSIS PATIENTS N°	about 250 patients at KfH Kreuzburger Straße Nuremberg and KfH Virnsberger Straße (associated with Nuremberg) and 1) Medizinische Klinik IV, Erlangen: 8 beds 2) Medizinische Klinik, Nürnberg: 20 beds
PERITONEAL DIALYSIS PATIENTS N°	approx 30 patients
INTENSIVE CARE NEPHROLOGY BEDS N°	8 (Erlangen) and 14 (Nuremberg)
RENAL TRANSPLANTS /YEAR (2004) N°	approx 90

CLINICAL RESEARCH

BASIC RESEARCH


Erlangen - City View	Erlangen University Campus


Erlangen Unit	Nuremberg Unit