EUROPEAN TRAINING CENTRES

  
Piazza Duomo
Parma
Palazzo Ducale

 

Department of Clinical Medicine, Nephrology and Health Science Unit of Nephrology, Parma, Italy

 

HEADS OF THE DEPARTMENT
Prof. Carlo Buzio
CLINICAL STAFF

Landino Allegri, Lucia Bignardi, Ariberto Corradi, Salvatore David, Maria Elena Ferrari, Umberto Maggiore, Luigi Melfa, Marilena Minari.
RESEARCH AND LABORATORY

Luisa Carnevali, Claudio Casoli.

 

CONTACT INFORMATION
E-MAIL
carlo.buzio@unipr.it
PHONE:
+39-0521-702345
FAX:
+39-0521-292627
FULL POSTAL ADDRESS
Dipartimento di Clinica Medica, Nefrologia e Scienze della Prevenzione.

Azienda Ospedale/Università. Via Gramsci 14, 43100 Parma, Italy

WEBSITE OF THE UNIT http://www.unipr.it/arpa/nefrolog/

 

CLINICAL FACILITIES
NEPHROLOGY AND INTERNAL MEDICINE BEDS N° 16
HEMODIALYSIS PATIENTS N° 100
PERITONEAL DIALYSIS PATIENTS N° 11
INTENSIVE CARE NEPHROLOGY BEDS N° 2
RENAL TRANSPLANTS /YEAR (2005) N° 60

 

RESEARCH INTERESTS

CLINICAL RESEARCH

RESEARCH PROGRAMMES AND PROJECTS LIST

• Alterations of collagen chains in patients with chronic acquired glomerulopathies: tissue mRNA levels and protein expression, urinary loss.

• Genomics in understanding the pathogenesis of hereditary human glomerular diseases.

• Gene alterations that underlie human renal and urinary tract malformations.

• Treatment of patients with idiopathic retroperitoneal fibrosis: randomized prospective trials.

• Immunotherapy in the treatment of patients with renal cell carcinoma: randomized trials prospective.

• Iperparathyroidism in chronic renal failure – Effect of vitamin D in mild CKD.

• Cardiovascular disease in CKD – Pulse wave velocity, arterial stiffness echocardiographic findings in chronic renal failure in different therapeutic regimens.

• Haemodialysis and haemodiafiltration: Bicarbonate kinetics in dialysis.

• Immunological monitoring in kidney transplant.

• Prediction models for the allocation of kidneys from marginal donors.

• Pulmonary disease associated with immunosoppressive drugs.

• Nutrition in acute renal failure.

• Anti-haemostatic strategies for renal replacement therapy in criticall ill patients.

• Antimicrobials' pharmacokinetic  in patients with acute renal failure.

• Prediction models for outcome in patients with acute renal failure.

• Acute renal failure from iodinated contrast media.

 

BASIC RESEARCH

RESEARCH PROGRAMMES AND PROJECTS LIST 

• Early adaptation mechanisms of the medullary thick ascending Henle loops in the pre-hypertensive phase of the SHR rats.

• Oxidative stress oxidative and efficiency of peritoneal dialysis.

 

Peer Reviewed Publications in International Journals (only English) 2002-2006

Publications list

Ghiggeri G.M., Catarsi P., Scolari F., Caridi G., Bertelli R., Carrea A., Sanna Cherchi S., Emma F., Allegri L., Cancarini G., Tizzoni G.F., Perfumo F. Cyclosporine in patients with steroid-resistant nephrotic syndrome: an open-label, nonrandomized, retrospective study. Clin. Ther. 26; 1411-1418; 2004
Oleggini R., Bertelli R., Di Donato A., Di Duca M., Caridi G., Sanna-Cherchi S., Scolari F., Murer L., Allegri L.,  Coppo R., Emma F., Camussi G., Perfumo F., Ghiggeri G.M.: Rare functional variants of podocin (NPHS2) promoter in patients with nephrotic sindrome.Gene Expression 13(1); 59-66; 2006

Rastaldi MP, Candiano G, Musante L, Bruschi M, Armelloni S, Rimoldi L, Tardanico R, Sanna Cherchi S, Ferrario F, Montinaro V, Haupt R, Parodi S, Carnevali ML, Allegri L, Camussi G,  Gesualdo L, Scolari F and Ghiggeri GM.: Glomerular clusterin is associated with PKC-a/b regulation and good outcome of membranous glomerulonephritis in humans. Kidney Int. 70(3); 477-485; 2006

Sanna-Cherchi S., Somenzi D., Carnevali ML., Pilato FP., Carraio M., Ghiggeri GM:, Allegri L. Recurrent autosomal-dominant focal segmental glomerulosclerosis. Kidney Int. 2006 (in press)
Vaglio A, Manenti L, Allegri L, Ferrozzi F,  Corradi D, Buzio C. ANCA-positive periaortic vasculitis: does it fall within the spectrum of vasculitis? J Intern Med 2002;251:268-71.
Ronda N, Gatti R, Giacosa R, Raschi E, Testoni C, Meroni PL, Buzio C, Orlandini G. Anti-fibroblast antibodies (AFA) from systemic sclerosis patients are internalized by fibroblast via a caveolin-linked pathway. Arthritis Rheum 2002;46(6):1595-1601.
Vaglio A, Corradi D, Manenti L, Ferretti Stefania, Garini Giovanni, Buzio C. Evidence of  autoimmunity in chronic periaortitis: a prospective study. Am J Med 2003;114:454-62.
Ronda N, Bernini F, Giacosa R, Gatti R, Baldini N, Buzio C, Orlandini G. Normal human IgG prevents endothelial cell activation induced by TNFalpha and oxidized low-density lipoprotein atherogenic stimuli. Clin Exp Immunol 2003;133(2):219-26.
Buzio L, De Palma G, Mozzoni P, Tondel M, Buzio C, Franchini I, Axelson O, Mutti A. Glutathione S-transferases M1-1 and T1-1 as risk modifiers for renal cell cancer associated with occupational exposure to chemicals. Occup Environ Med 2003;60(10):789-93.
Vaglio A, Buzio L, Cravedi P, Pavone L, Garini G, Buzio C. Prognostic significance of albuminuria in patients with renal cell cancer. J Urol 2003;170:1135-7.

Vaglio A, Corradi D, Manenti L, Buzio C. Is autoimmune thyroiditis a systemic disease? Am J Med  (correspondence) 2003;115:413-4.
Vaglio A, Corradi D, Ronda N, Garini G, Buzio C. Large bowel obstruction heralding Churg-Strauss syndrome Am J Gastroenterol 2004;99:562-3.

Greco P, Vaglio A, Manenti L, Corradi D, Ferrozzi F, Ferretti S, Cortellini P, Buzio C. La fibrosi retroperitoneale idiopatica. Giornale Italiano di Nefrologia 2004;21:84-9.

Fineschi S, Borghi MO, Riboldi P, Gariglio M, Buzio C, Landolfo S, Cebecauer L, Tuchynova A, Rovensky J, Meroni PL.Prevalence of autoantibodies against structure specific recognition protein 1 in systemic lupus erythematosus. Lupus 2004;13:463-8.
Corradi D, Vaglio A, Maestri R, Legname V, Leonardi G, Bartoloni G, Buzio C. Eosinophilic myocarditis in a patient with idiopathic hypereosinophilic syndrome: Insights into mechanisms of myocardial cell death. Hum Pathol 2004;35:1160-3.

Giacosa R., Santi R., Vaglio A., Pavone L., Ferrozzi F., Passalacqua R., Buzio C.Passalacqua R., Buzio C. “Late” regression of metastases from renal cancer after a period of disease progression continuing the same intermittent low dose immunotherapy regimen. Acta Biomed Ateneo Parmense 2004;75:126-30.

Sartore-Bianchi A.,  Soriani A., Mattioni R., Vaglio A., Buzio C., Porta C. Low doses of subcutaneous interleukin-2 plus interferon-alfa do not induce thyroid function alterations in advanced renal cell carcinoma. Oncol Rep 2004;12:855-9.

Allegri L., Garini G., Benozzi L., Cravedi P., Buzio C. L’interessamento renale nelle vasculiti sistemiche. La granulomatosi di Wegener. Progressi in Reumatologia 2004;5:244-56.

Garini G., Allegri L., Vaglio A., Buzio C. La glomerulonefrite crioglobulinemica associata ad infezione da virus dell’epatite C. Progressi in Reumatologia 2004;5:265-73

Vaglio A., Buzio C. Chronic periaortitis: a spectrum of diseases. Curr Opin Rheumatol 2005;17:34-40.
Vaglio A., Versari A., Fraternali A., Ferrozzi F., Salvarani C., BuzioC. (18)F-flurodeoxyglucose positron emission tomography in the diagnosis and follow-up of idiopathic retroperitoneal fibrosis. Arthritis Rheum 2005;53:122-5.
Tumiati B, Zuccoli G, Pavone L, Buzio C. ENT Wegener's granulomatosis can hide severe central nervous system involvement Clin Rheumatol. 2005 Jun;24(3):290-3. Epub 2004 Nov 26

Vaglio A, Greco P, Versari A, Filice A, Cobelli R, Manenti L, Salvarani C, Buzio C. Post-treatment residual tissue in idiopathic retroperitoneal fibrosis: active residual disease or silent  "scar" ? A study using 18F-fluorodeoxyglucose positron emission tomography. Clin Exp Rheumatol. 2005 Mar-Apr;23(2):231-4.
Salvarani C, Pipitone N, Versari A, Vaglio A, Serafini D, Bajocchi G, Salvo D, Buzio C, Greco P, Boiardi L. Positron emission tomography (PET): evaluation of chronic periaortitis. Arthritis Rheum. 2005 Apr 15;53(2):298-303.
Ronda N, Cravedi P, Benozzi L, Lunghi P, Bonati A, Allegri L, Carnevali ML, Caserta C, Borghetti A, Buzio C. Early proinflammatory activation of renal tubular cells by normal and pathologic IgG. Nephron Exp Nephrol. 2005;100(2):e77-84. Epub 2005 Mar 17.

Sinico RA, Di Toma L, Maggiore U, Bottero P, Radice A, Tosoni C, Grasselli C, Pavone L, Gregorini G, Monti S, Frassi M, Vecchio F, Corace C, Venegoni E, Buzio C. Prevalence and clinical significance of antineutrophil cytoplasmic antibodies in Churg-Strauss syndrome. Arthritis Rheum. 2005 Sep;52(9):2926-35.

      
Greco P, Vaglio A, Corradi D, Cobelli R, Zompatori M, Buzio C.Tuberculosis as a trigger of retroperitoneal fibrosis Clin Infect Dis. 2005 Oct 1;41(7):e72-5.
Garini G, Allegri L, Vaglio A, Buzio C. Hepatitis C virus-related cryoglobulinemia and glomerulonephritis: pathogenesis and    therapeuticstrategies. Ann Ital Med Int. 2005 Apr-Jun;20(2):71-80. Review.
Pesci A, Pavone L, Buzio C, Manganelli P. Respiratory system involvement in ANCA-associated systemic vasculitides. Sarcoidosis Vasc Diffuse Lung Dis. 2005 Dec;22 Suppl 1:S40-8. Review.
Vaglio A, Greco P, Corradi D, Palmisano A, Martorana D, Ronda N, Buzio C. Autoimmune aspects of chronic periaortitis. Autoimmun Rev. 2006 Aug;5(7):458-64.
Secondary and Primar Vasculitides (Se.Pri.Va) Study Group. Pavone L, Grasselli C, Chierici E, Maggiore U, Garini G, Ronda N, Manganelli P, Pesci A, Rioda WT, Tumiati B, Pavesi G, Vaglio A, Buzio C; Outcome and prognostic factors during the course of primary small-vessel vasculitides. J Rheumatol. 2006 Jul;33(7):1299-306.
Garini G, Allegri L, Carnevali ML, Iannuzzella F, Buzio C. Successful treatment of severe/active cryoglobulinaemic membranoproliferative glomerulonephritis associated with hepatitis C virus infection by means of the sequential administration of immunosuppressive and antiviral agents. Nephrol Dial Transplant. 2006 Jun 17; [Epub ahead of print]
Capocasale E, Busi N, Valle RD, Mazzoni MP, Bignardi L, Maggiore U, Buzio C, Sianesi M. Octreotide in the treatment of lymphorrhea after renal transplantation: a preliminary experience. Transplant Proc. 2006 May;38(4):1047-8.
Bacciu A, Bacciu S, Mercante G, Ingegnoli F, Grasselli C, Vaglio A, Pasanisi E, Vincenti V, Garini G, Ronda N, Ferri T, Corradi D, Buzio C. Ear, nose and throat manifestations of Churg-Strauss syndrome. Acta Otolaryngol. 2006 May;126(5):503-9.
Sinico RA, Di Toma L, Maggiore U, Tosoni C, Bottero P, Sabadini E,Giammarresi G, Tumiati B, Gregorini G, Pesci A, Monti S, Balestrieri G, Garini G, Vecchio F, Buzio C. Renal involvement in Churg-Strauss syndrome. Am J Kidney Dis. 2006 May;47(5):770-9.
Vaglio A., Greco P., Buzio C. Tamoxifen therapy for retroperitoneal fibrosis. Ann Intern Med. 2006 Apr 18;144(8):619-20.
Martorana D, Vaglio A, Greco P, Zanetti A, Moroni G, Salvarani C, Savi M, Buzio C, Neri TM. Chronic periaortitis and HLA-DRB1*03: another clue to an autoimmune origin. Arthritis Rheum. 2006 Feb 15;55(1):126-30.
Vaglio A.., Salvarani C., Buzio C. Retroperitoneal fibrosis. Lancet. 2006 Jan 21;367(9506):241-51. 
Borghi L, Meschi T, Maggiore U, Prati B. Related Articles, Links Dietary therapy in idiopathic nephrolithiasis. Nutr Rev. 2006 Jul;64(7 Pt 1):301-12. Review.
Fiaccadori E, Maggiore U, Rotelli C, Giacosa R, Parenti E, Picetti E, Manini P, Andreoli R, Cabassi A. Does haemodialysis significantly affect serum linezolid concentrations in critically ill patients with renal failure? A pilot investigation. Nephrol Dial Transplant. 2006 May;21(5):1402-6.
Fiaccadori E, Maggiore U, Rotelli C, Giacosa R, Parenti E, Cabassi A, Ariya K, Wirote L. Thrombotic-thrombocytopenic purpura following malaria prophylaxis with mefloquine. J Antimicrob Chemother. 2006 Jan;57(1):160-1.
Fiaccadori E, Maggiore U, Rotelli C, Giacosa R, Picetti E, Parenti E, Meschi T, Borghi L, Tagliavini D, Cabassi A. Effects of different energy intakes on nitrogen balance in patients with acute renal failure: a pilot study. Nephrol Dial Transplant. 2005 Sep;20(9):1976-80.
Maggiore U, Cristol JP, Canaud B, Dupuy AM, Formica M, Pozzato M, Panichi V, Consani C, Metelli MR, Sereni L, De Nitti C, David S, Tetta C Comparison of 3 automated assays for C-reactive protein in end-stage renal disease: clinical and epidemiological implications. J Lab Clin Med. 2005 Jun;145(6):305-8.
Guerra A, Allegri F, Meschi T, Adorni G, Prati B, Nouvenne A, Novarini A, Maggiore U, Fiaccadori E, Borghi L. Effects of urine dilution on quantity, size and aggregation of calcium oxalate crystals induced in vitro by an oxalate load. Clin Chem Lab Med. 2005;43(6):585-9.
Fiaccadori E, Maggiore U, Rotelli C, Giacosa R, Parenti E, Picetti E, Sagripanti S, Manini P, Andreoli R, Cabassi A. Removal of linezolid by conventional intermittent hemodialysis, sustained low-efficiency dialysis, or continuous venovenous hemofiltration in patients with acute renal failure. Crit Care Med. 2004 Dec;32(12):2437-42.
Meschi T, Maggiore U, Fiaccadori E, Schianchi T, Bosi S, Adorni G, Ridolo E, Guerra A, Allegri F, Novarini A, Borghi L. The effect of fruits and vegetables on urinary stone risk factors. Kidney Int. 2004 Dec;66(6):2402-10.
Panichi V, Maggiore U, Taccola D, Migliori M, Rizza GM, Consani C, Bertini A, Sposini S, Perez- Garcia R, Rindi P, Palla R, Tetta C. Interleukin-6 is a stronger predictor of total and cardiovascular mortality than C-reactive protein in haemodialysis patients. Nephrol Dial Transplant. 2004 May;19(5):1154-60.
Fiaccadori E, Maggiore U, Rotelli C, Giacosa R, Lombardi M, Sagripanti S, Buratti S, Ardissino D, Cabassi A. Related Articles, Links  Plasma and urinary free 3-nitrotyrosine following cardiac angiography procedures with non-ionic radiocontrast media. Nephrol Dial Transplant. 2004 Apr;19(4):865-9.  
Fiaccadori E, Maggiore U, Giacosa R, Rotelli C, Picetti E, Sagripanti S, Melfa L, Meschi T, Borghi L, Cabassi A. Enteral nutrition in patients with acute renal failure. Kidney Int. 2004 Mar;65(3):999-1008.
Fiaccadori E, Maggiore U, Rotelli C, Giacosa R, Ardissino D, De Palma G, Bergamaschi E, Mutti A. Acute renal and hepatic failure due to accidental percutaneous absorption of 1,2-dichlorpropane contained in a commercial paint fixative. Nephrol Dial Transplant. 2003 Jan;18(1):219-20.

Borghi L, Meschi T, Schianchi T, Allegri F, Guerra A, Maggiore U, Novarini A. Medical treatment of nephrolithiasis. Endocrinol Metab Clin North Am. 2002 Dec;31(4):1051-64, x. Review.

Sisca S, Maggiore U. Beneficial effect of icodextrin on the hypertriglyceridemia of CAPD patients. Perit Dial Int. 2002 Nov-Dec;22(6):727-9.

Ronco C, Brendolan A, Lonnemann G, Bellomo R, Piccinni P, Digito A, Dan M, Irone M, La Greca G, Inguaggiato P, Maggiore U, De Nitti C, Wratten ML, Ricci Z, Tetta C. A pilot study of coupled plasma filtration with adsorption in septic shock. Crit Care Med. 2002 Jun;30(6):1250-5.

Fiaccadori E, Maggiore U, Rotelli C, Minari M, Melfa L, Cappe G, Cabassi A. Continuous haemofiltration in acute renal failure with prostacyclin as the sole anti-haemostatic agent. Intensive Care Med. 2002 May;28(5):586-93. Epub 2002 Mar 20.

Borghi L, Schianchi T, Meschi T, Guerra A, Allegri F, Maggiore U, Novarini A. Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria N Engl J Med. 2002 Jan 10;346(2):77-84.

Fiaccadori E, Maggiore U, Rotelli C, Minari M, Melfa L, Cappe G, Cabassi A. Continuous haemofiltration in acute renal failure with prostacyclin as the sole anti-haemostatic agent. Intensive Care Med. 2002 May;28(5):586-93.

Minari M, Maggiore U, Tagliavini D, Rotelli C, Cabassi A, David S, Fiaccadori E. Severe acute valproic acid intoxication successfully treated with hemodiafiltration without hemoperfusion. Ann Emerg Med. 2002 Feb;39(2):204-5. No abstract available.

Bussolati B, David S, Cambi V, Tobias PS, Camussi G. URINARY SOLUBLE CD14 MEDIATES HUMAN PROXIMAL TUBULAR EPITHELIAL CELL INJURY INDUCED BY LPS. Int J Mol Med. 2002 Oct;10(4):441-9.
Combarnous F, Tetta C, Chapuis Celier C, Wratten ML. Custaud MA, De Catheu T, Fouque  D, David S, Carraro G, Laville M. ALBUMIN LOSS IN ON-LINE HAEMODIAFILTRATION Int J Artif Organs. 2002 Mar;25(3):203-9.
David S, Gerra D, De Nitti C, Bussolati B, Teatini U, Longhena GR, Guastoni C, Bellotti N, Combarnous F, Tetta C. HEMODIAFILTRATION AND HIGH-FLUX HEMODIALYSIS WITH POLYETHERSULFONE MEMBRANES. Contrib Nephrol. 2003;(138):43-54

Poli D, Pavone L, Tansinda P, Goldoni M, Tagliavini D, David S, Mutti A, Franchini I ORGANIC CONTAMINATION IN DIALYSIS WATER: TRICHLOROETHYLENE AS A MODEL COMPOUND. Nephrol, Dial Transplant 2006 Jun;21(6):1618-25. Epub 2006 Feb 20.

Pizzarelli F, David S, Sala P, Icardi A, Casani A IRON-REPLETE HAEMODIALYSIS PATIENTS DO NOT REQUIRE HIGHER ERYTHROPOIETIN DOSAGES WHEN CONVERTING FROM SUBCUTANEOUS TO INTRAVENOUS ADMINISTRATION.  RESULTS OF THE ITALIAN STUDY ON ERYTHROPOIETIN CONVERTING (ISEC). Am J Kidney Dis 2006 Jun;47(6):1027-35
Tetta C, David S, Marcelli D, Cogliati P, Formica M, Inguaggiato P, Panichi V. CLINICAL EFFECTS OF ONLINE DIALYSATE AND INFUSION FLUIDS. Hemodial Int. 2006 Jan;10 Suppl 1:S60-6.
 


European Fellows programme

Specify if the Unit accepts fellows from European countries for:
Short (1-2 month) well focused training programs either clinically or laboratory oriented:
Long (at least 1 year) research fellowships:
Specify corresponding availability of grants: No.
Specify if the Unit may provide help for accommodation: No.

Prerequisites for Fellowship

Language: English, Italian.

Work/Research experience

Other prerequisites