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Santander |
| University Hospital | ||
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1929 |
1998 |
2005 |
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Santander |
| University Hospital | ||
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1929 |
1998 |
2005 |
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| HEAD OF THE UNIT | Dr Manuel Arias Rodriguez |  |
| CLINICAL STAFF | Angel
Luis Martín De Francisco |
 |
| RESEARCH STAFF |  |
| CONTACT
INFORMATION |
|
| nefarm@humv.es, nefrologia@humv.es | |
| PHONE: | +34-942-202738 |
| FAX: | +34-942-320415 |
| FULL POSTAL ADDRESS | Servicio de Nefrologia, Hospital Valdecilla, Avda de Valdecilla s/n, Santander, Spain |
| WEBSITE OF THE UNIT | https://193.146.74.4 |
| WEBSITE OF THE HOSPITAL | http://www.humv.es |
| CLINICAL
FACILITIES |
|
| NEPHROLOGY BEDS N° | 17 |
| HEMODIALYSIS PATIENTS N° | 120 |
| PERITONEAL DIALYSIS PATIENTS N° | 40 |
| RENAL TRANSPLANTS /YEAR (2002) N° | 41 |
RESEARCH INTERESTS
CLINICAL RESEARCH
Epidemiology
of Chronic Renal Failure
Cardiovascular Risk In Kidney Transplant Recipients
Arterial Hypertension In the Cantabria Region
RESEARCH
PROGRAMMESS AND PROJECTS LIST
Anti-HLA antibodies after kidney transplantation
Histological markers of chronic allograft nephropathy
BASIC RESEARCH
Experimental models of transplant alloreactivity and tolerance: regulatory cells and apoptosis.
RESEARCH
PROGRAMMESS AND PROJECTS LIST
Cooperative Spanish Nextwork of Investigation in Organ Transplantation.
Peer Reviewed Publications in International Journals (only English) 2000-2003
Publications list
2003
| A
Pharmacokinetic Conversion Study of GENGRAFR and NEORALR in Stable Renal
Transplant Recipients: Preliminary Report Frei U, Scheuermann E, Oppenheimer,
Arias M, An der Woude F, Rodicio J, Stahl R, Meek K, Awni W, Nabulsi
A, Hoffman R Clinical Transplantation. 2003, (en prensa). |
| Antiproteinuric
efficacy of losartan in comparison with amlodipine in non-diabetic proteinuric
renal diseases: a double-blind, randomized clinical trial Praga M, Fernández
Andrade C, Luño J, Arias M, Poveda R, Mora J, Valles M, Rivera
F, Galceran JM, Martinez Ara J, Aguirre R, Bernis C, Marin R, Campistol
JM Nephrology, Dialysis & Transplantation. 2003; vol. 18: p. 1806-1813 |
| Assesment
of glomerular filtration rate in tansplant recipients with severe renal
insufficiency by Nankivell, Modification of Diet in Renal Disease (MDRD),
and Cockroft-Gault equations Rodrigo E, Fernández-Fresnedo G,
Ruiz JC, Piñera C, Heras M, De Francisco ALM, Sanz de Castro
S, Cotorruelo JG, Zubimendi JA, Arias M Transplantation Proceedings. 2003; vol. 35: p. 1671-1672 |
| Bone
disease in long term adult kidney transplant patients with normal renal
function Montalban C, De Francisco ALM, Mariñoso ML, Zubimendi
JA, García Unzueta M, Amado JA, Arias M Kidney International. 2003; vol. 63; supl. 85: p. 129-132 |
| Clinical
relevance of posttransplantation HLA antibody monitoring by ELISA Fernández-Fresnedo
G, Pastor JM, López-Hoyos M, De Francisco ALM, Rodrigo E, Cotorruelo
JG, Zubimendi JA, Ruiz JC, Piñera C, Herráez I, Arias
M Transplantation Proceedings. 2003; vol. 32: p. 701 |
| Comparison
between a two-drug regimen with tacrolimus and steroids and a triple
one with azathioprine in kidney transplantation: results of a European
trial with 3-year follow up Pascual J, Segoloni G, Gonzalez Molina M,
Del Castillo D, Capdevila L, Arias M, García J, Ortuño
J Transplantation Proceedings. 2003; vol. 35: p. 1701-1703 |
| Early
elimination of cyclosporine in kidney transplant recipients receiving
sirolimus prevents progression of chronic pathologic allograft lesions
Ruiz JC, Campistol JM, Mota A, Prats D, Gutierrez JA, Castro A, García
J, Morales JM, Griño JM, Gomez JM, Arias M Transplantation Proceedings. 2003; vol. 35: p. 1669-1670 |
| Effect
of early graft function on patient survival in renal transplantation
Fernández-Fresnedo G, Rodrigo E, Escallada R, De Francisco ALM,
Zubimendi JA, Ruiz JC, Cotorruelo JG, Arias M Transplantation Proceedings. 2003; vol. 35: p. 1653-1654 |
| Hb Santander
(B34(B16)Val -->Asp (GTC -->GAC)): A New Unstable Variant Found
as a De novo Mutation in a Spanish Patient Villegas A, Ropero P, Nogales
A, Gonzánez FA, Mateo M, Mazo E, Rodrigo E, Arias M Hemoglobin. 2003; vol. 27: p. 31-35 |
| Health-Related
quality-of-life outcomes of sirolimus-treated kidney transplant patients
after rlimination of cyclosporine A: results of a 2-year randomized
clinical trial Oberbauer R, Hutchison B, Eris J, Arias M, Calesson K,
Mota A, Kreis H, Kleinman L, Wang F, Chen J, Revicki DA Transplantation. 2003; vol. 75: p. 1277-1285 |
| Impact
of the delayed grat function in hypersensitized kidney transplant patients
Arias M Transplantation Proceedings. 2003; vol. 35: p. 1655-1657 |
| Inhibition
of B cell dealth causes the development of an IgA nephropathy in (NZW
x C57BL/6)F1-bcl-2 transgenic mice Diez MA, Marquina R, López-Hoyos
M, Buelta L, Kuroki A, Kikuchi S, Villegas J, Philgren M, Siegrist CA,
Arias M, Izui S, Merino J, Merino R Journal Center Investigation. 2003, (en prensa). |
| Modulation
of autoantibody production by mycophenolate mofetil:effects on the development
of SLE in (NZBxNZW)F1 mice Ramos A, Piñera C, Setién M,
Buelta L, De Cos MA, De Francisco ALM, Merino R, Arias M Nephrology, Dialysis & Transplantation. 2003; vol. 18: p. 878-883 |
| Posttransplant
diabetes is a cardiovascular risk factor in renal transplant patients
Fernández-Fresnedo G, Escallada R, De Francisco ALM, Rodrigo
E, Zubimendi JA, Ruiz JC, Piñera C, Herráez I, Arias M
Transplantation Proceedings. 2003; vol. 35: p. 700 |
| Pulse
pressure is an independent risk factor of cardiovascular disease in
renal transplant patients Fernández-Fresnedo G, Escallada R,
Rodrigo E, De Francisco ALM, Sanz de Castro S, Ruiz JC, Piñera
C, Cotorruelo JG, Arias M Transplantation Proceedings. 2003; vol. 35: p. 1730-1731 |
| Quantitation
of 24-hour urine protein excretion in kidney transplant patients by
the use of protein to creatinine ratio Rodrigo E, Piñera C, Ruiz
JC, Fernández-Fresnedo G, Escallada R, Herráez I, Cotorruelo
JG, Zubimendi JA, De Francisco ALM, Sanz de Castro S, Arias M Transplantation Proceedings. 2003; vol. 35: p. 702 |
| Relationship
of donor-specific class-I anti-HLA antibodies detected by ELISA after
kidney transplantation on the development of acute rejection and graft
survival Fernández-Fresnedo G, Pastor JM, López-Hoyos
M, Ruiz JC, Zubimendi JA, Cotorruelo JG, Rodrigo E, De Francisco ALM,
Arias M Nephrology, Dialysis & Transplantation. 2003; vol. 18: p. 990-995 |
2002
| 4 Acute
rejection in the elderly recipient: Influence of age in the outcome
of kidney transplantation Palomar R, Ruiz JC, Zubimendi JA, Cotorruelo
JG, De Francisco ALM, Ruiz JC, Rodrigo E, Sanz de Castro S, Fernández-Fresnedo
G, Arias M Geriatric Nephrology Urology. 2002; vol. 33: p. 145-148 |
| Apolipoprotein
CIII and E polimorphisms and cardiovascular disease, hyperlipidemia
and insulin resistance in renal transplantation Rodrigo E, González-Lamuño
D, Ruiz JC, Fernández-Fresnedo G, Isla D, Cotorruelo JG, Zubimendi
JA, De Francisco ALM, García-Fuentes M, Arias M American Journal of Transplantation. 2002; vol. 2: p. 343-348 |
| Association
Between the Sstl Polymorphism of the Apolipoprotein C-III Gene, Glucose
Intolerance and Cardiovascular Risk in Renal Transplant Recipients Rodrigo
E, González-Lamuño D, Ruiz JC, Fernández-Fresnedo
G, Isla D, Cotorruelo JG, Zubimendi JA, De Francisco ALM, García
Fuentes M, Arias M Transplantation Proceedings. 2002; vol. 34: p. 379 |
| Early
Cyclosporine A withdrawal in kidney transplant recipients under a sirolimus-based
immunosuppressive regimen: Pathological study of graft biopsies at one
year postransplant Ruiz JC, Campistol JM, Mota A, Prats D, Gutiérrez
A, Castro A, Pinto JR, García J, Morales JM, Grynió JM,
Arias M Transplantation Proceedings. 2002; vol. 34: p. 92-93 |
| Efficacy
and Safety of Tacrolimus Compared with Cyclosporine Microemulsion in
Kidney Transplantation: a randomised multicentre study Margreiter R,
Arias M, et cols The Lancet. 2002; vol. 359: p. 741-746 |
| Efficacy
and Safety of Tacrolimus Compared with Cyclosporine Microemulsion in
Kidney Transplantation: Twelve-Month Follow-up Montagnino G, Arias M,
et cols Transplantation Proceedings. 2002; vol. 34: p. 1635-1637 |
| Histopathological
findings according to Banff-97 classification system comparing tacrolimus
versus cyclosporine Rodrigo E, Escallada R, Fernández-Fresnedo
G, Ruiz JC, Piñera C, Herráez I, Cotorruelo JG, Zubimendi
JA, De Francisco ALM, Arias M Transplantation Proceedings. 2002; vol. 34: p. 1719-1720 |
| Is There
Any Correlation Between Pathologic Changes for Acute Rejection in Kidney
Transplant (Banff 97) and Graft Function? Palomar R, Ruiz JC, Zubimendi
JA, Cotorruelo JG, Hernández E, Rodrigo E, Val-Bernal F, Arias
M Transplantation Proceedings. 2002; vol. 34: p. 349 |
| Measurement
of renal function in pre-ESRD patients Rodrigo E, De Francisco ALM,
Escallada R, Ruiz JC, Fernández-Fresnedo G, Piñera C,
Arias M Kidney International. 2002; vol. 61; supl. 80: p. 11-17 |
| Parathyroidectomy
in dialysis patients De Francisco ALM, Fernández-Fresnedo G,
Rodrigo E, Piñera C, Amado JA, Arias M Kidney International. 2002; vol. 61; supl. 80: p. 161-166 |
| Past present
future of eryhtropoietin in the elderly De Francisco ALM, Fernández-Fresnedo
G, Rodrigo E, Piñera C, Heras M, Palomar R, Ruiz JC, Arias M
Geriatric Nephrology Urology. 2002; vol. 33: p. 187-193 |
| Persistent
proteinuria as a useful parameter to distinguish between chrolinc renal
rejection and cyclosporin nephrotoxicity Fernández-Fresnedo G,
Escallada R, Rodrigo E, Piñera C, De Francisco ALM, Ruiz JC,
Cotorruelo JG, Zubimendi JA, Arias M Transplantation Proceedings. 2002; vol. 34: p. 365-366 |
| Proteinuria
is an independent risk factor of cardiovascular disease in renal transplant
patient Fernández-Fresnedo G, Escallada R, Rodrigo E, Piñera
C, De Francisco ALM, Cotorruelo JG, Sanz de Castro S, Arias M Transplantation Proceedings. 2002; vol. 34: p. 367 |
| Return
to dialysis after renal transplant. What would be the best way? Arias
M, Escallada R, De Francisco ALM, Rodrigo E, Fernández-Fresnedo
G, Setién M, Piñera C, Ruiz JC, Herráez I, Cotorruelo
JG Kidney International. 2002; vol. 61; supl. 80: p. 85-88 |
| Short-Term
combination of mycophenolate mofetil with cyclosporine as a therapeutic
option for neal transplant recipients Sadek S, Medina J, Arias M, Sennesael
J, Squifflet B, Vogt B Transplantation. 2002; vol. 74: p. 511-517 |
| Significance
of age in the survival of diabetic patient after kidney transplantation
Fernández-Fresnedo G, Zubimendi JA, Cotorruelo JG, De Francisco
ALM, Ruiz JC, Rodrigo E, Heras M, Piñera C, Arias M Geriatric Nephrology Urology. 2002; vol. 33: p. 173-177 |
| The risk
of cardiovascular disease associated with proteinuria transplant patients
Fernández-Fresnedo G, Escallada R, Rodrigo E, De Francisco ALM,
Cotorruelo JG, Sanz de Castro S, Zubimendi JA, Arias M Transplantation. 2002; vol. 73: p. 1345-1348 |
2001
| Analysis
of Primary and Recurrent Rejection Following Renal Transplantation in
a large, Comparative, Multicentre Trial Arias M, et cols (Study Group)
Transplantation Proceedings. 2001; vol. 33: p. 1259-1261 |
| Basiliximab
Significantly Reduces Acute Rejection in Renal Transplant Patients Given
Triple with Azathioprine Arias M, et cols (Study Group) Transplantation Proceedings. 2001; vol. 33: p. 1009-1010 |
| Clinical
markers and modifiable cardiovascular risk factors after kidney transplantation
Arias M, Fernández-Fresnedo G Transplantation Proceedings. 2001; vol. 33: p. 3677-3678 |
| Clinical
significance of anti-HLA antibodies determined by new methods after
kidney transplantation López-Hoyos M, Fernández-Fresnedo
G, Pastor JM, Arias M Revista Portuguesa de Nefrología e Hipertensao. 2001; vol. 15: p. 63-69 |
| Clinical
validation of the Banff 97 classification for the diagnosis of rejection
in kidney transplantation Palomar R, Ruiz JC, Zubimendi JA, Pérez-Expósito
MA, Val-Bernal F, Arias M Transplantation Proceedings. 2001; vol. 33: p. 3309 |
| Effect
of apolipoprotein E and C-III polymorphisms on lipid profile and cardiovascular
risk in renal trasplant recipients Rodrigo E, González-Lamuño
D, Isla D, Fernández-Fresnedo G, Ruiz JC, Piñera C, Herráez
I, Arias M Transplantation Proceedings. 2001; vol. 33: p. 3676 |
| Effects
of Mycophenolate Mofetil in the development of systemic lupus erythematosus
in (NZBxNZW)F1 mice Ramos A, Piñera C, Cibrián E, Buelta
L, De Cos MA, De Francisco ALM, Merino R, Arias M Transplantation Proceedings. 2001; vol. 33: p. 3316-3317 |
| Hypertension
and long-term renal allograft survival: effect of early glomerular filtration
rate Fernández-Fresnedo G, Palomar R, Escallada R, De Francisco
ALM, Cotorruelo JG, Zubimendi JA, Sanz de Castro S, Ruiz JC, Rodrigo
E, Arias M Nephrology, Dialysis & Transplantation. 2001; vol. 16; supl. 1: p. 105-109 |
| Proteinuria
as a useful clinical marker of cyclosporine nephrotoxicity in renal
transplant patients Fernández-Fresnedo G, Escallada R, Rodrigo
E, Zubimendi JA, De Francisco ALM, Herráez I, Arias M Transplantation Proceedings. 2001; vol. 33: p. 3373-337 |
2000
| B lymphopenia
in uremia is related with an accelerated in vitro apoptosis and dysregulation
of Fas and Bcl-2 Fernández-Fresnedo G, Ramos A, López-Hoyos
M, González-Pardo C, De Francisco ALM, Arias M Nephrology, Dialysis & Transplantation. 2000; vol. 15: p. 502-510 |
| Changes
in serum concentrations of matrix metalloproteinases in kidney transplantation
Rodrigo E, López-Hoyos M, Escallada R, Ruiz JC, Fernández-Fresnedo
G, Heras M, Piñera C, Ramos MA, Cotorruelo JG, Arias M Transplantation Proceedings. 2000; vol. 32: p. 517-518 |
| Circulating
levels of matrix metalloproteinases MMP-3 and MMP-2 in renal transplant
recipients with chronic transplant nephropathy Rodrigo E, López-Hoyos
M, Escallada R, Fernández-Fresnedo G, Ruiz JC, Piñera
C, Cotorruelo JG, Zubimendi JA, De Francisco ALM, Arias M Nephrology, Dialysis & Transplantation. 2000; vol. 15: p. 2041-2045 |
| Hemodiafiltration
with on-line endogenous reinfusion De Francisco ALM, Piñera C,
Heras M, Rodrigo E, Fernández-Fresnedo G, Ruiz JC, Tetta C, Arias
M Blood Purification. 2000; vol. 18: p. 231-236 |
| Hemodiafiltration
with online regeneration of ultrafiltrate De Francisco ALM, Ghezzi PM,
Brendolan A, Fiorini F, La Greca G, Ronco C, Arias M, Gervasio R, Tetta
C Kidney International. 2000; vol. 58; supl. 76: p. 66-71 |
| Immunohistochemical
study of a new experimental model of acute cellular xenograft rejection
Ramos A, Vega A, Val-Bernal F, Chávez G, López-Hoyos M,
Ruiz JC, De Francisco ALM, Castillo J, Gómez Fleitas M, Arias
M Transplantation Proceedings. 2000; vol. 32: p. 960 |
| Removal
of xenoreactive antibodies by protein-A immunoadsorption: experience
in 22 patients Ramos A, Ruiz JC, De Francisco ALM, Fleitas MG, Arias
M Xenotransplantation. 2000; vol. 7: p. 14-20 |
| Tacrolimus
is highly effective in both dual and triple therapy regimens following
renal transplantation Segolomi G, Bonomini V, Maresca MC, Arisi L, González-Molina
M, Tarantino A, Del Castillo D, Ortuño J, Carmellini M, Capdevila
L, Arias M, García J, Rogotti P, Ruiz JC, for the Spanish and,
Italian Tacrolimus Study, Group Transplant International. 2000; vol. 13; supl. 1: p. 336-340 |
European
Fellows programme
Specify
if the Unit accepts fellows from European countries for:
Short (1-2 month) well focused training programs either clinically or
laboratory oriented: Yes.
Long (at least 1 year) research fellowships: Yes.
Specify corresponding availability of grants: No.
Specify if the Unit may provide help for accommodation: No.
Prerequisites for Fellowship
Language: Spanish, English
