EUROPEAN TRAINING CENTRES

 

solingen1
solingen2
Solingen

Department of Nephrology, Solingen General Hospital, University of Cologne, Germany

Solingen – the Cutting Edge of  Germany
Solingen is internationally known as the town with the Cutting Edge. The name of the town is also a registered trademark for high-quality knives and scissors. Geographically speaking Solingen belongs to the Bergisches Land; culturally it is at home in the Rhineland and politically it is part of Northrhine-Westphalia.
 
The economic structure of the town has changed over the last decades. Blades and cutting implements are still a major factor and over 90% of German manufacturers of scissors, razors and cutlery are located here. Other industries have also been attracted to Solingen, and the town now plays a leading role in surface treatment technologies, such as galvanizing and anodizing.
 
Solingen’s industrial history is not immediately apparent. The predominant colour is green and the standard of living is high. There is no classic town centre; instead Solingen has numerous ”village centres” and rural settlements which have grown together beside the major traffic routes along the ridges and streams. The valleys in between have never been fully developed and now provide green oases in the urban environment. The rugged forests of the hills along the River Wupper form the Eastern and Southern boundaries of the town.
 
A host of tourist attractions can easily be reached. Old workshops along the Wupper bear witness to the heydays of sword, knife and blade production and to the cottage industry of sharpening and grinding. The bridge at Müngsten is a superb engineering achievement from 1897 and remains the highest railway bridge in Germany to this day.

 

 

HEAD OF THE DEPARTMENT Peter Heering MD, PhD, Professor of Medicine heering
CLINICAL STAFF

Dr. W. Heizer, Dr. S Bartel-Kuß, Dr. R Siewert, Dr. G. Bär, Dr Stefanie Bischoff, Dr Rainer Fischer, Dr Anne Geursen, Dr Regine Heitmann, Dr Marc Johnson, Marco Leschniewski, G. Meister; Dr Christoph Schlaugat, Dr Kai Strassmann, Dr S Schulenburg

RESEARCH AND LABORATORY Peter Heering MD, PhD, Professor of Medicine
 

Priv.- Doz. J. Heinrich PhD

 

CONTACT INFORMATION
E-MAIL heering@klinikumsolingen.de
PHONE: +49-212-547-2418
FAX: +49-212-547 2254
FULL POSTAL ADDRESS Solingen General Hospital, University of Cologne, Dept of
Nephrology, Gotenstr. 1, 42653 Solingen, Germany
WEBSITE www.klinikumsolingen.de/kliniken/nephrologie/index.html

 

CLINICAL FACILITIES
   
NEPHROLOGY BEDS N° 66
HEMODIALYSIS PATIENTS N° 75
PERITONEAL DIALYSIS PATIENTS N°

20
INTENSIVE CARE NEPHROLOGY BEDS N° 4
8 intermediate care beds, full nephrological care incuding all extracorporal therapy for the following ICU' s: internal medicine, abdominal and trauma surgery, anesthesiology, neurosurgery

 

RESEARCH INTERESTS

CLINICAL RESEARCH
RESEARCH PROGRAMS AND PROJECT LIST

1. Inflammation and atherosclerosis in end-stage renal disease
2. Optimizing treatment in chronic renal failure, dialysis and hypertension
3. Cardio-vascular complications of chronic renal failure
4. Acute renal failure, pathophysiology, diagnosis and treatment.
5. Principles of diagnosis and treatment of glomerular diseases focussing on genetic effects and therapeutic studies.
 

BASIC RESEARCH
RESEARCH PROGRAMS AND PROJECT LIST

1. The role of metabolic acidosis  in renal disorders. pathophysiolgy and treatment
2. Tubular disorders in pathophysiolgy and clinical surrounding.
3. Cytokines in chronic inflammation


Peer Reviewed Publications in International Journals (only English) 2000-2004

2004
 
Bantis C, Heering P, Luther Y, Aker S, Kuhr N, Grabensee B, Ivens K.
Influence of cytokine gene polymorphisms on focal segmental glomerulosclerosis (FSGS).
American Journal of Nephrology 2004; 24: 427-431
 
Bantis C, Heering P, Aker S, Klein-Vehne N, Grabensee B, Ivens K. Association of
interleukin-10 gene G-1083A polymorphism with the progession of primary
glomerulonephritis. Kidney International 2004; 66: 288-294
 
Bantis C, Ivens K, Klein-Vehne N, Grabensee B, Heering P. Einfluss genetischer
Polymorphismen des Renin Angiotensin Systems auf die membranöse Glomerulonephritis.
Nieren und Hochdruckkrankheiten 2004; 4: 167-176
 
Bantis C, Ivens K, Kreusser W, Koch M, Klein-Vehne N, Grabensee B, Heering P. Influence
of genetic polymorphisms of the renin-angiotensin System on IgA nephropathy. American
Journal of Nephrology 2004; 24 (2): 258-267
 
Brause M, Grabensee B, Heering P. Strategies fort the treatment of acute renal failure in
intensive care units: the aspect of dosing. Renal Failure 2004, 26 (3); 209-213
 
Heering P, Kurschat C, Vo D, Klein-Vehne N, Fehsel K, Ivens K. Aldosterone resistance in
kidney transplantation is in part induced by a down-regulation of mineralocorticoid receptor
expression. Clinical Transplantation 2004; 18 (2): 186-192
 
Heering P, Braun N, Müllejans R, Ivens K, Zäuner I, Fünfstück R, Keller F, Krämer B,
Schollmeyer P, Risler T, Grabensee B. Cyclosporine A and Chlorambucil in the treatment of
idiopathic focal segmental glomerulo-sclerosis. American Journal of Kidney Diseases, 2004, 
43, 1, 10-18
 
Heering P, Klein-Vehne N, Fehsel K. Decreased mineralcorticoid-receptor expression in
blood cells of kidney-transplanted patients under immunosuppressive therapy – cost-efficient

determination by quantitative PCR. Journal of Clinical Pathology 2004, 57: 33-36
 
2003
 
Luther Y, Bantis C, Ivens K, Grabensee B, Heering P: Effects of the genetic polymorphisms
of the renin-angiotensin-aldosteron-system on focal segmental Glomerulonephritis. Kidney

and Blood Pressure Research 2003, 26:333-337
 
C. Waldner, G. Heise, J. Meyer-Kirchrath, K. Schrör, B. Grabensee, P. Heering: Selective
cyclooxygenase-2 inhibition upregulates renal cortical av integrin expression.
Nephron Exp. Nephrology 2003; 93:e72-e79
 
M. Brause, A. Neumann, T. Schumacher, B. Grabensee, P. Heering: Effects of filtration-
volume of continous venovenous hemofiltration in the treatment of patients with acute renal

failure in intensive care units. Crit Care Med. 2003; 31:  841 – 846
 
Luther Y, Bantis C, Ivens K, Fehsel K, Kolb-Bachhofen V, Heering P: Effects of the genetic
polymorphisms of the renin-angiotensin-system on FSGS. Kidney & Blood Pressure
Research, 2003;  26:  333 - 337
 
C. Waldner, G. Heise, K. Schroer, P. Heering: COX-2 inhibition and prostaglandin receptors
in experimental nephritis. European Journal of Clinical Investigation, 2003, 33 (11):969-975
 
B. Luther, A. Weinbrenner, K. Grabitz, P. Heering, W. Sandmann: Die juvenile
Arteriosklerose – Suchtmittelfolge oder genetische Determination? Springer Verlag,
Gefäßchirurgie 1 - 2003 8:29-35
 
C. Kurschat, P. Heering, B. Grabensee: Gitelman-Syndrom: Eine wichtige
Differenzialdiagnose der Hypokaliämie. Deutsche Medizinische Wochenschrift 2003; 128
(22):1225-1228
 
P. Heering, B. Grabensse, M. Brause: Cytokine removal in septic patients with continuous

venovenous hemofiltration. Kidney Blood Pressure Research 2003; 26 (2):128-134
 
Heering P, Brause M: Therapie des akuten Nierenversagens – Fußangeln der Therapie.
Intensivmed. und Notfallmedizin 2003;   40:1-8
 
2002
 
Brause M, Neumann A, Schumacher T, Grabensee B, Heering P. Effect of filtration volume
of continuous hemofiltration in the treatment of patients with acute renal failure in intensive
care units. Critical Care Medicine, im Druck
 
Deppe C, Heering P, Viengchareun S, Grabensee B, Farman N, Lombes M. Cyclosporine A
and FK506 inhibit transcriptional activity of the human mineralocorticoid receptor: A cell
based model to investigate partial aldosterone resistance in kidney transplantation.
Endocrinology 2002; 143: 1932 - 1941
 
Heering P, Deppe CE, Farokhzad F, Helmchen U, Grabensee B.Hemolytic uremic syndrome
after renal transplantation:Immunosuppressive therapy with rapamycin. Nephron 2002; 91:
 
C. M. Schannwell, K. Ivens, H. Quassdorff, B. Grabensee, P. Heering, M. Leschke, B. E.
Strauer: Regression der linksventrikulären Hypertrophie und Verbesserung der diastolischen
Funktion bei terminaler Niereninsuffizienz nach Nierentransplantation – eine prospektive

echokardiographische Untersuchung. Journal für Kardiologie 2002; 9.: 231 - 237
 
2001
Aker S, P. Heering, E. Kinne-Saffran, B. Grabensee, R.K.H. Kinne. Different effects of
cyclosporine A and FK 506 on potassium transport systems in MDCK cells. Experimental
Nephrology 2001; 9: 332 - 340
 
Blume C, Hollenbeck M, Ivens K, Heering P, Hetzel GR, Grabensee B. Conversion of
immunosuppression from cyclosporine to tacrolimus due to steroid resistant acute rejection or
ongoing chronic rejection in kidney allograft recipients. Transplant Proceed 2001; 33: 3161 - 3163
 
Brause M, Grabensee B, Heering P. Elimination von Mediatoren durch kontinuierliche 
Nierenersatzverfahren. Intensivmedizin 2001, 39: 471 - 478
 
Gradaus F, Ivens K, Peters A, Heering P, Schoebel F, Grabensee B, Strauer BE.
Angiographic progression of coronary artery disease in patients with end stage renal disease.
Nephrology Dialysis Transplantation 2001; 16: 1198 - 1202
 
Heering P, Brause M, Ivens K, Grabensee B. Kontinuierliche Hämofiltration - mehr als ein
Therapieverfahren für das akute Nierenversagen ? Zeitschrift f. Intensiv- und
Notfallbehandlung 2001; 26: 53 – 59
 
Heering P, Brause M, Plum J, Grabensee B. Reaction to icodextrine. Peritoneal Dialysis Int
2001; 21: 321 - 322
 
Heering P, Schneider A, Grabensee B, Plum J. Einfluß von Cyclosporin A auf die
Nierenfunktion in der Therapie der Glomerulonephritis. Deutsche Med. Wochenschrift  2001;
126: 1093 - 1098
 
Ivens K, Gradaus F, Heering P, Schoebel FC, Klein M, Schulte HD, Strauer BE, Grabensee
B. Myocardial revascularization in patients with end-stage renal disease: Comparison of
percutaneous transluminal coronary angioplasty and coronary artery bypass grafting. Int J

Urol Nephrol 2001; 32, S. 717 - 723, 2001.
 
Hetzel GR, Plum J, Oeczan F, Heering P, Grabensee B. Transforming growth factor  beta1
plasma levels in stable renal allograft under different immunosuppression. Transplantation
2001; 71: 586 – 587
 
Oeczan F, Sabel M, Heering P. Grabensee B, Sekundäre Glomerulonephritis bei chronischer
Infektion es ventriculo-atrialen shunts.  Deutsche Med. Wochenschrift 2001; 126: 1229 - 1232
 
Poll L, May P, Koch JA, Hetzel G, Heering P, Mödder U. HRCT findings of amiodarone
pulmonary toxicity: clinical and radiological regression. J Cardiovasc Pharmacol Ther 2001;
6: 307 - 311
 
Reinhard T, Reis A, Bohringer D, Malinowski M, Voiculescu A, Heering P, Godehardt E,
Sundmacher R. Systemic mycophenolate mofetil in comparison with CsA in high risk
keratoplasty. Graefes Arch Exp Clin Ophthalmology 2001; 239: 367 – 372
 

2000
 
Aker S, Ivens K, Grabensee B, Heering P. Akutes Nierenversagen nach Hantavirus-Infektion

Med. Klinik 2000; 95: 189 - 194
 
Brause M, Heering P, Grabensee B. Akutes Nierenversagen. Notfallmedizin 2000; 26: 338 - 343
 
Heise G, Grabensee B, Strauer BE, Heering P. Diagnostik und Therapie bei 7 Patienten mit

Amitryptillin Intoxikation. Zeitschrift f. Intensivmedizin 2000; 32: 475 - 481
 
Hetzel GR, Schneider P, Mondry A, Heering P, Heyll A, Grabensee B. Therapy options in
systemic AL-Amyloidosis with renal involvement. Deutsche Med Wochenschrift 2000; 125: 997 - 1002
 
Hetzel GR, Malms J, Heering P, Mödder U, Grabensee B. Post transplant distal limb bone
marrow edema: MR imaging and thereuptic options. Nephrology, Dialysis Transplantation

2000; 15: 1859 - 1864
 
Ivens K, Heering P, Klein M, Schulte H, Grabensee B. Kardiochirurgische Therapie der
Herzklappenerkrankung bei Patienten mit terminaler Niereninsuffizienz. Nieren- und

Hochdruck 2000; 29: 577 - 584
 
Klusmann A, Ivens K, Schadewaldt P, Grabensee B, Heering P.  Homocystein als
kardiovaskulärer Risikofaktor bei Patienten mit terminaler Niereninsuffizienz. Med. Klinik

2000; 95: 189 - 194
 

 

European Fellows programme  
   
Specify if the Unit accepts fellows from European countries for:  
   

Short (1-2 month) well focused training programs either clinically or laboratory oriented: Yes
 

 
Long (at least 1 year) research fellowships: Yes

 
 
Specify corresponding availability of grants: To be discussed individually (clinical training position may be available for 6 or 12 monthts when residency places are unoccupied).
   

Specify if the Unit may provide help for accommodation: Yes

 
   

Prerequisites for Fellowship

  
   
Language: For clinical activity German knowledge is helpful; for clinical and basic research English is sufficient.

 

  
Work/Research experience: MD or PhD.  
   
Other prerequisites (specify): applications should include a curriculum vitae (CV) indicating the rationale and the content of the training requested, and a support letter by the head of the home department.