EUROPEAN TRAINING CENTRES

Vicenza

RESEARCH INTERESTS

RESEARCH PROGRAMMES AND PROJECTS LIST
RESEARCH LIST
• SRD protocol: Clinical prospective randomized controlled trial on coupled filtration/adsorption + CVVH versus CVVH alone in critically ill patients with multiple organ failure.
• Technical and clinical evaluation of a new extracorporeal system for removal of circulating endotoxin in patients with sepsis.
• Retrospective analysis of the population treated with CRRT: high dose versus low dose of dialysis outcome.
• BEST Kidney: approach to initiation and withdrawal from CRRT in ICU patients.
• International survey on CRRT: results from a questionnaire collected during the international course on critical care nephrology.
• Study on the effect of prolonged extracorporeal circulation with cardiac arrest in the genesis of SIRS-MOF in cardiac surgery patients.
• Prospective clinical study on acute rahbdomyolysis and plasma-filtration adsorption.
• Effects of CVVH on the HELLP syndrome.
• Project on teledialysis for CRRT: on-line monitoring of physiological parameters and machine operational parameters.
• Clinical cross-over trial on the use of a endotoxin-adsorbing system (polymixin-B coated membrane) in patients on septic shock. Effects on hemodynamics.
• Clinical cross-over study on the use of heparin coated circuits versus standard circuits in patients undergoing CRRT. Effects on filter survival and coagulation parameters.
• Effects of hematocrit on extracorporeal solute clearances in hemodialysis. The search for optimal target hematocrit.
• Study on blood flow distribution in hollow fiber hemodialyzers characterized by a new helical scanning technique.
• Study on a new sorbent cartridge designed to selectively remove beta-2-microglobulin.
• Study MPO: Multicentric trial on membrane permeability outcome.
• Study HFR: Multicentric trial on hemodiafiltration with rigeneration of the ultrafiltrate in paired filtration dialysis.
• Peak concentration hypothesis in patients with sepsis.
• Apoptosis generated by ultrafiltrate of uremic and septic sera.
• Hemolipodialysis in patients with acute liver failure.
• Internal filtration in the new Polysulfone membrane Helixone.
• In Vitro analysis of the new hyperpermeable FH membrane.
• Prospective cross over study on optimal combination between low and high flux membranes in hemodialysis. The concept of a weekly therapy.
• Experimental evaluation of a new plasma extraction device designed to provide the basis for extracorporeal treatments in acute and chronic patients.
• Experimental “flush peritoneal dialysis”. A double lumen catheter PD system to increase the efficiency of PD in long dwell and short dwell exchange regimens.
• Effects of hematocrit on peritoneal dialysis clearances for different molecules.
• Analysis of the impact of different dialysate compartment configurations on dialysate flow distribution in hollow fiber dialyzers. Clearance and imaging studies.
• Study on diffusion-ultrafiltration profiles in hollow fiber dialyzers utilized in hemodialysis and hemodiafiltration. Analysis of segmental concentrations of dialysate along the length of the dialyzer.
• Study on filtration-backfiltration behaviour in hollow fibers equipped with polysulfone fibers of 200 and 185 micra inner diameter. Functional study and scintigraphic imaging.
• Use of blood volume measurement to monitor ultrafiltration in congestive heart failure.
• New Catheter for continuous flow peritoneal dialysis.

Peer Reviewed Publications in International Journals (only English) 2000-2003

 

European Fellows programme

Specify if the Unit accepts fellows from European countries for:
Short (1-2 month) well focused training programs either clinically or laboratory oriented: we prefer minimum 3 months.
Long (at least 1 year) research fellowships: 6 months to 12 months is the ideal time.
Specify corresponding availability of grants: No
Specify if the Unit may provide help for accommodation: Yes

Prerequisites for Fellowship

Language: English, Spanish, Italian

Work/Research experience: Peritoneal dialysis, Hemodialysis and critical care nephrology.