European Training Centres

Würzburg

Bayerische-Julius-Maximilans University,

Department of Medicine, Division of Nephrology
Würzburg, Germany

HEAD OF THE UNIT	Christoph Wanner, MD
CLINICAL STAFF	Faculty: Jan Galle MD, Eckehard Heidbreder MD Internal Medicine Board Members: F Breunig, Korhammer M, Lopau K, Schlottog B, MD's in training: Berger M, Krane V, Lindner T, Metzger T, Mönks D, Naujoks H, Quaschning T, Raff U, Seibold S, Schneider R, Schwedler S Junior positions: Knoll A, Swoboda F, Uelger Z International training fellowship: Al-Shami T
RESEARCH AND LABORATORY	Grants by (MD+PhD): Berger M, Breunig F, Galle J, Heimpel S, Heinloth A, Krane V, Lindner T, Mönks D, Quaschning T, Schneider R, Schwedler S, Raff U, Wanner C

CONTACT INFORMATION

E-MAIL	Wanner_C@klinik.uni-wuerzburg.de
PHONE:	+49 931 201 36331
FAX:	+49 931 201 36502
FULL POSTAL ADDRESS	Josef-Schneider-Str. 2, 97080 Wuerzburg, Germany

CLINICAL FACILITIES

NEPHROLOGY BEDS N°	26 beds
TRANSPLANT UNIT BEDS N°	4 beds
HEMODIALYSIS PATIENTS N°	15 dialysis beds KfH outpatient center / 180 patients
PERITONEAL DIALYSIS PATIENTS N°	32 CAPD patients (back-up center for 60 PD patients)
INTENSIVE CARE NEPHROLOGY BEDS N°	We cover 4 ICUs and may cover up to 12 if required (>1000 ICU dialysis + CVVHD)
RENAL TRANSPLANTS /YEAR (2001) N°	40

RESEARCH INTERESTS

Patient oriented research and basic research: Inflammation, Oxidative stress, Atherosclerosis, Endothelial dysfunction in renal disease, Risk-factor epidemiology, Molecular genetics, Diabetic nephropathy, Genetic field working, Fabry disease.

RESEARCH PROGRAMMES

Grant driven projects. Grants available until (see dates below): - 09/2003 Molecular genetics of diabetic nephropathy - 03/2002 Genetic epidemiology and genetics of complex diseases: genetics of type 2 Diabetes in Germany - 05/2004 Identification of risk factors for cardiovascular disease in type 2 diabetics with chronic renal failure - 08/2002 Genetic field working to identify families and their risk factors for cardiovascular diseae in 4D - 03/2004 Die Deutsche Diabetes Dialyse Studie (4D-study) - 06/2001 Irbesartan diabetic nephropathy trial (IDNT-trial) - 03/2004 (SECRET-Study) - 06/2001 Influence of oxidative stress by high-flux dialysis - 09/2001 Immunpathogenesis of Goodpasture Syndrome: characterisation of B-cell and T-cell-epitopes on alpha 3 NC1 domain of type IV collagen - 12/2001 Interaction of angiotensin II and atherogenic lipoproteins in the pathophysiologic influence of
human endothelial cells, human mesangial cells and isolated arteries - 08/2002 Pathomechanisms and therapy of renal failure - 04/2003 Signal transduction of oxidative stress and apoptosis induced by atherogenic lipoproteins in macrophages, vascular and renal cells - 01/2003 Effects of the vasopeptidase inhibitor M100240 on endothelial function and neurohumoral
substances in renovascular hypertension in comparison with the ACE Inhibitor Ramipril. - 06/2003 ERT in Fabry disease: evaluation of renal and cardiac disease - 02/2004 Interaction of angiotensin II with atherogenic lipoproteins: relevance for cell growth and vascular dysfunction - 10/2004 Molecular basis of high factor VIII-levels in thromboembolic complications - 10/2004 Influence of modified and native CRP on development of atherosclerosis and of endothelial
dysfunction in Apo E-knockout mice

Peer Reviewed Publications in International Journals (only English) 2000-2002

European Fellows programme

Short (1-2 month) well focused training programs either clinically or laboratory oriented: 1998-2002, 5 fellows trained from Lithuania, Rumania, Hungary, Tcheck (grant possibilities exist over the Universtity of Wuerzburg or the Kuratorium der Gesellschaft für Nephrologie (www.gfn-online.com). Accomodation may be provided by the University on request.

Long (at least 1 year) research fellowships: 1 ISN Fellow trained in 2000, individual arrangements (maximum 2 fellows/year).

Prerequisites for Fellowship
Language: For clinical activities German knowlegde is mandatory; for research training spoken English expertise is sufficient. Applications can be made by sending a curriculum vitae (CV) indicating the rationale and the content of the training requested. A support letter by the head of the home University should accompany the application letter.