SUBJECT CONSULTANT REVIEW

Title of the article

Transplant glomerulopathy: subclinical incidence and association with alloantibody.

Authors

Gloor JM, Sethi S, Stegall MD, Park WD, Moore SB, Degoey S, Griffin MD, Larson TS, Cosio FG.

Journal
Am J Transplant. 2007 Sep;7(9):2124-32. Epub 2007 Jul 3.
Subject Consultant
B. Watschinger
Score (1 to 3 stars)
**
Comments
The results of this protocol biopsy based retrospective study of 582 renal transplants lead the authors to suggest that subclinical TG is an under-recognized cause of antibody-mediated, chronic renal allograft injury, associated with acute rejection, pretransplant hepatitis C antibody positivity and anti-HLA antibodies (especially anti-Class II).