SUBJECT CONSULTANT REVIEW

Title of the article
Improvement in long-term renal graft survival due to CMV prophylaxis with oral ganciclovir: results of a randomized clinical trial.
Authors

Kliem V, Fricke L, Wollbrink T, Burg M, Radermacher J, Rohde F.

Journal
Am J Transplant. 2008 May;8(5):975-83. Epub 2008 Feb 5.
Subject Consultant
B. Watschinger
Score (1 to 3 stars)
***
Comments
From this prospective randomized trial of 148 renal graft recipients it is concluded that oral prophylaxis may improve long-term graft survival for most renal transplant patients and that preemptive therapy can be considered in low risk patients in combination with adequate CMV monitoring.