| Title
of the article |
Bortezomib provides effective therapy for antibody- and cell-mediated acute rejection.
|
| Authors |
Everly MJ, Everly JJ, Susskind B, Brailey P, Arend LJ, Alloway RR, Roy-Chaudhury P, Govil A, Mogilishetty G, Rike AH, Cardi M, Wadih G, Tevar A, Woodle ES. |
| Journal
|
Transplantation. 2008 Dec 27;86(12):1754-61. |
| Subject
Consultant |
B. Watschinger |
| Score
(1 to 3 stars) |
*** |
| Comments |
Bortezomib a first in class proteosomal inhibitor for the treatment of multiple myeloma was succefully used as an antirejection strategy targeting plasma cells. This is a new strategy that could prove potentially successful in the future. |