| Title
of the article |
Donor-specific antibody levels and three generations of crossmatches to predict antibody-mediated rejection in kidney transplantation. |
| Authors |
Riethmüller S, Ferrari-Lacraz S, Müller MK, Raptis DA, Hadaya K, Rüsi B, Laube G, Schneiter G, Fehr T, Villard J. |
| Journal
|
Transplantation. 2010 Jul 27;90(2):160-7. |
| Subject
Consultant |
B. Watschinger |
| Score
(1 to 3 stars) |
** |
| Comments |
The study evaluated the prognostic impact of pretransplant donor-specific anti-human leukocyte antigen antibodies (DSA) detected by single-antigen beads and compared the three generations of crossmatch (XM) tests in kidney transplantation. In sensitized recipients, the best prediction of AMR and consecutively reduced graft function is delivered by DSA-I alone at high strength or by DSA-I at low strength in combination with the LXM or CXM. |
