SUBJECT CONSULTANT REVIEW

Title of the article
Comparative Effects of Benidipine and Amlodipine on Proteinuria, Urinary 8-OHdG, Urinary L-FABP, and Inflammatory and Atherosclerosis Markers in Early-Stage Chronic Kidney Disease.
Authors
Nakamura T, Sato E, Fujiwara N, Kawagoe Y, Ueda Y, Sugaya T, Yamagishi S, Yamada S, Koide H.
Journal
Am J Med Sci. 2010 Feb;339(2):157-163.
Subject Consultant
A. Wiecek
Score (1 to 3 stars)
**
Comments
Benidipine is more effective than amlodipine for protecting renal function and potentially for ameliorating atherosclerosis in hypertensive patients with mild CKD. T-type calcium channel blockers may be effective in patients with CKD.